Zobrazeno 1 - 10
of 396
pro vyhledávání: '"HFD, High Fat Diet"'
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Autor:
Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Dioxin-like molecules have been associated with endocrine disruption and liver disease. To better understand aryl hydrocarbon receptor (AHR) biology, metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd0117be990219f236c36406e5afea7
https://doi.org/10.1016/j.apsb.2021.10.014
https://doi.org/10.1016/j.apsb.2021.10.014
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Due to its safety, convenience, low cost and good compliance, oral administration attracts lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory bioavailability in the gastrointestinal tract. One of the critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d001e27a816f9de7d75ff16dd2143ec
http://www.sciencedirect.com/science/article/pii/S2211383520307279
http://www.sciencedirect.com/science/article/pii/S2211383520307279
Autor:
Eman Kolieb, Shymaa Ahmed Maher, Mohammed Nader Shalaby, Amnah Mohammed Alsuhaibani, Afaf Alharthi, Wael A. Hassan, Karima El-Sayed
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 21; Pages: 13740
The prevalence of obesity has risen in the last decades, and it has caused massive health burdens on people’s health, especially metabolic and cardiovascular issues. The risk of vitamin D insufficiency is increased by obesity, because adipose tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b002974af5037660b1695efbb82aa2e
https://pubmed.ncbi.nlm.nih.gov/36360622
https://pubmed.ncbi.nlm.nih.gov/36360622
Autor:
Zhengcai Ju, Lin-shan Jiang, Xunjiang Wang, Wendong Huang, Zhengtao Wang, Siming Sun, Eryun Zhang, Lili Ding, Tong Tian, Qiaoling Yang, Li Yang, Yangmeng Wang, Yingbo Yang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1541-1554 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Obesity and its associated complications are highly related to a current public health crisis around the world. A growing body of evidence has indicated that G-protein coupled bile acid (BA) receptor TGR5 (also known as Gpbar-1) is a potential drug t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f45516d038bca9fd9338d0a4c987b9
http://www.sciencedirect.com/science/article/pii/S2211383521001106
http://www.sciencedirect.com/science/article/pii/S2211383521001106
Autor:
Noha M. Abogresha, Ghada Abdel Kader, Sahar M Greish, Dalia A. Eltamany, Hanaa S. Sallam, Eman Z. Abdelaziz
Publikováno v:
Saudi Journal of Biological Sciences, Vol 28, Iss 5, Pp 2956-2963 (2021)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Highlights • Obesity contributes to male infertility. • Can lycopene or moringa improve male infertility? • Tested in a rodent model of diet-induced obesity. • Lycopene was superior to Moringa in improving male fertility parameters.
Obes
Obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022a318963a786fe573cc3d8302d936
https://doi.org/10.1016/j.sjbs.2021.02.034
https://doi.org/10.1016/j.sjbs.2021.02.034
Autor:
Yuxiao Liu, Xiaozhen Dai, Xiao-Lin Liu, Aoyuan Cui, Feng Shen, Feng-Zhi Xin, Weitong Su, Jian-Gao Fan, Yamei Han, Ze-Hua Zhao, Feifei Zhang, Yaqian Xue, Yu Li, Genxiang Cai, Zhengshuai Liu, Zi-Xuan Wang, Qin Pan, Jinyun Bai, Zhimin Hu, Tian-Yi Ren, Fengguang Ma, Da Zhou
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 857-871 (2021)
Background and Aims Butyric acid is an intestinal microbiota-produced short-chain fatty acid, which exerts salutary effects on alleviating nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism of butyrate on regulating hepatic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4e846e48b3e395486746888e372063
https://doi.org/10.1016/j.jcmgh.2021.05.006
https://doi.org/10.1016/j.jcmgh.2021.05.006
Publikováno v:
Journal of Advanced Research, Vol 27, Iss, Pp 127-135 (2021)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Background Over the last several decades, hydrogen sulfide (H2S) has been found to exert multiple physiological functions in mammal systems. The endogenous production of H2S is primarily mediated by cystathione β-synthase (CB
Background Over the last several decades, hydrogen sulfide (H2S) has been found to exert multiple physiological functions in mammal systems. The endogenous production of H2S is primarily mediated by cystathione β-synthase (CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4f72879a610d4ef2b815d4fcf07fdd
https://doi.org/10.1016/j.jare.2020.05.010
https://doi.org/10.1016/j.jare.2020.05.010
Autor:
Yatrik M. Shah, Shogo Takahashi, Sadeesh K. Ramakrishnan, Raja Gopal Reddy Mooli, Frank J. Gonzalez, Sumeet Solanki, Jessica Rodriguez
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 585-597 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Fatty liver or nonalcoholic fatty liver disease (NAFLD) is the most common liver disease associated with comorbidities such as insulin resistance and cardiovascular and metabolic diseases. Chronic activation of hypoxic signaling, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d8ab9d3e6c8736a8ba6e7154654a18
https://doi.org/10.1016/j.jcmgh.2021.03.011
https://doi.org/10.1016/j.jcmgh.2021.03.011
Autor:
Irina A. Kirpich, Banrida Wahlang, Nicholas C. Alexander, Xiaohong Li, Matthew C. Cave, Eric C. Rouchka
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 536-547 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Aroclor1260 worsened diet-induced steatohepatitis in CAR and PXR knockout mice. • CAR and PXR ablation increased gut microbiome diversity and modified composition. • Improved bacterial diversity did not prot
Highlights • Aroclor1260 worsened diet-induced steatohepatitis in CAR and PXR knockout mice. • CAR and PXR ablation increased gut microbiome diversity and modified composition. • Improved bacterial diversity did not prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39015a534cdc9d853739a1ae71598521
http://www.sciencedirect.com/science/article/pii/S2214750021000512
http://www.sciencedirect.com/science/article/pii/S2214750021000512