Zobrazeno 1 - 10
of 930
pro vyhledávání: '"HEXOKINASE-II"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background Glycometabolism and lipid metabolism are critical in cancer metabolic reprogramming. The primary aim of this study was to develop a prognostic model incorporating glycometabolism and lipid metabolism-related genes (GLRGs) for accu
Externí odkaz:
https://doaj.org/article/4f2b1110e3b442c3be1c973842860bf3
Autor:
Kui Wu, Wei Gong, Huanmei Sun, Wenjiao Li, Li Chen, Yingchun Duan, Jianlong Zhu, Hu Zhang, Huihui Ke
Publikováno v:
Cancer Reports, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Background ARHGAP10 is a tumor‐suppressor gene related to ovarian cancer (OC) progression; however, its specific mechanism is unclear. Aims To investigate the effect of ARHGAP10 on OC cell migration, invasion, and glycolysis. Methods and R
Externí odkaz:
https://doaj.org/article/e2319c5bf45b462488d837a88cb32417
Autor:
Guohui Han, Xiangdong Bai, Feng Li, Li Huang, Yating Hao, Weina Li, Peng Bu, Huanhu Zhang, Xinxin Liu, Jun Xie
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23827- (2024)
Increasing evidence has demonstrated the oncogenic roles of long non-coding RNA (lncRNA) hepatocellular carcinoma (HCC)-associated long non-coding RNA (HANR) in the development of HCC and lung cancer; however, the involvement of HANR in triple-negati
Externí odkaz:
https://doaj.org/article/72ab7c81d513402687e15bd540e4e9e4
Akademický článek
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Publikováno v:
Molecules, Vol 29, Iss 1, p 75 (2023)
Increased glycolysis is a key characteristic of malignant cells that contributes to their high proliferation rates and ability to develop drug resistance. The glycolysis rate-limiting enzyme hexokinase II (HK II) is overexpressed in most tumor cells
Externí odkaz:
https://doaj.org/article/cd5bb1b42cd54043abec8cb723d49f9c
Akademický článek
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Publikováno v:
Cancer Management and Research, Vol Volume 13, Pp 8063-8076 (2021)
Xiao-Hong Chen,1 Ding-Li Yu,2 Jiang-Tao Zhong,2 Shui-Hong Zhou,2 Jun Fan,3 Zhong-Jie Lu4 1Department of Otolaryngology, The Second Hospital of Jiaxing (The Second Affiliated Hospital, Jiaxing University), Jiaxing City, Zhejiang Province, 314000, Peop
Externí odkaz:
https://doaj.org/article/1a72f15802a9443fac103a80c7f38eda
Autor:
Thaís Oliveira, Douglas Lemos, Louise Jean, Jéssica M. Kawashima, Vitória R. de Azevedo, Eduardo J. Salustiano, Vivian M. Rumjanek, Robson Q. Monteiro
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chronic Myeloid Leukemia is a neoplastic disease characterized by the abnormal expansion of hematopoietic cells with compromised functions. Leukemic cells often display a multidrug resistance phenotype, enabling them to evade a number of structurally
Externí odkaz:
https://doaj.org/article/affe244631764dcda06459ab7769cdf6
Autor:
Damla Uludağ, Sadık Bay, Bilgesu Onur Sucu, Özgecan Şavluğ İpek, Thomas Mohr, Mustafa Güzel, Nihal Karakaş
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, hexokinase-II (HK-II) is i
Externí odkaz:
https://doaj.org/article/2f2e98f9bf9a49a594df53503809c75d
Autor:
Meng Shao, Jiayin Zhang, Jiahui Zhang, Hui Shi, Yu Zhang, Runbi Ji, Fei Mao, Hui Qian, Wenrong Xu, Xu Zhang
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background The stem cell factor SALL4 is reactivated in human cancers. SALL4 plays diverse roles in tumor growth, metastasis, and drug resistance, but its role in tumor metabolism has not been well characterized. Methods The glycolytic level
Externí odkaz:
https://doaj.org/article/2a2dde07e7034925b89cd85142becfd8