Vaccination: a History : From Lady Montagu to Genetic Engineering

Autor: Hervé Bazin

The history of vaccination is an important aspect of the history of mankind. Along with the development of hygiene, vaccinations have no doubt constituted the most outstanding advance in medicine. And yet, this subject that revolutionized both human

pH dependence of water anomaly temperature investigated by Eu(III) cryptate luminescence

Autor: Niko Hildebrandt, Jurriaan M. Zwier, Patricia Haro-González, Daniel Jaque, Carlos Mingoes, Lucía Labrador-Páez, Herve Bazin, F. Jaque

Publikováno v: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, Springer Verlag, 2019, 412, pp.73-80. ⟨10.1007/s00216-019-02215-0⟩
Analytical and Bioanalytical Chemistry, 2019, 412, pp.73-80. ⟨10.1007/s00216-019-02215-0⟩

International audience; Although water has been extensively studied, not all of its unique properties have been fully understood. There is still controversy about the temperature at which hydrogen bonds are broken or weakened, producing the anomalous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb841078d2512b47e0f24d5b9301e1bf
https://doi.org/10.1007/s00216-019-02215-0

Rat Hybridomas and Rat Monoclonal Antibodies (1990)

Autor: Herve Bazin

The purpose of this book is to provide information which supports the fact that rat hybridomas are no more difficult to develop than mouse hybridomas. This is the first book devoted to the development of rat hybridomas. It includes theories, step-by-

Time-resolved Fluorescence Resonance Energy Transfer (TR-FRET) to Analyze the Disruption of EGFR/HER2 Dimers

Autor: Caroline Bascoul-Mollevi, Christel Larbouret, Julie Vallaghe, Herve Bazin, David Azria, Nadège Gaborit, Thierry Chardès, Marie-Alix Poul, Gérard Mathis, Evelyne Crapez, Frédéric Peyrusson, André Pèlegrin

Publikováno v: Journal of Biological Chemistry. 286:11337-11345

In oncology, simultaneous inhibition of epidermal growth factor receptor (EGFR) and HER2 by monoclonal antibodies (mAbs) is an efficient therapeutic strategy but the underlying mechanisms are not fully understood. Here, we describe a time-resolved fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ebfa20851296ef537d05496b52b9347
https://doi.org/10.1074/jbc.m111.223503

Toward Efficient Drug Screening by Homogeneous Assays Based on the Development of New Fluorescent Vasopressin and Oxytocin Receptor Ligands

Autor: Laura Albizu, René Seyer, Maurice Manning, Thierry Durroux, Géraldine Teppaz, Hervé Ansanay, Herve Bazin, Bernard Mouillac

Publikováno v: Journal of Medicinal Chemistry. 50:4976-4985

A series of fluorescent ligands designed for vasopressin and oxytocin G protein-coupled receptors was synthesized and characterized to develop fluorescence polarization or homogeneous time-resolved fluorescence (HTRF) binding assays. These ligands, l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdac27b0b8d9510e707a43f6f0dfa2c0
https://doi.org/10.1021/jm061404q