Výsledky vyhledávání - "HERBERT LEPOR"

Akademický článek

High-risk prostate cancer treated with a stereotactic body radiation therapy boost following pelvic nodal irradiation

Autor: Jonathan W. Lischalk, Meredith Akerman, Michael C. Repka, Astrid Sanchez, Christopher Mendez, Vianca F. Santos, Todd Carpenter, David Wise, Anthony Corcoran, Herbert Lepor, Aaron Katz, Jonathan A. Haas

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

PurposeModern literature has demonstrated improvements in long-term biochemical outcomes with the use of prophylactic pelvic nodal irradiation followed by a brachytherapy boost in the management of high-risk prostate cancer. However, this comes at th

Externí odkaz: https://doaj.org/article/0ec567ed70034d06aa1ddb2c1679983f

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Akademický článek

Salvage Prostate Stereotactic Body Radiation Therapy After Definitive Cryoablation

Autor: Jonathan W. Lischalk, MD, Aaron E. Katz, MD, Seth R. Blacksburg, MD, MBA, Christopher Mendez, MA, Astrid Sanchez, MS, Michael C. Repka, MD, Matthew Witten, PhD, Samir Taneja, MD, Herbert Lepor, MD, Jonathan A. Haas, MD

Publikováno v: Advances in Radiation Oncology, Vol 7, Iss 3, Pp 100849- (2022)

Purpose: Whole gland cryoablation is a guideline-approved definitive treatment for localized prostate cancer, and is being explored for partial gland ablation. However, there is limited data regarding management of cryoablation failures. Stereotactic

Externí odkaz: https://doaj.org/article/0a5474b586bc44d69f199e22a36cb672

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Akademický článek

The role of TAp63γ and P53 point mutations in regulating DNA repair, mutational susceptibility and invasion of bladder cancer cells

Autor: Hsiang-Tsui Wang, Hyun-Wook Lee, Mao-wen Weng, Yan Liu, William C Huang, Herbert Lepor, Xue-Ru Wu, Moon-shong Tang

Publikováno v: eLife, Vol 10 (2021)

It has long been recognized that non-muscle-invasive bladder cancer (NMIBC) has a low propensity (20%) of becoming muscle-invasive (MIBC), and that MIBC carry many more p53 point mutations (p53m) than NMIBC (50% vs 10%). MIBC also has a higher mutati

Externí odkaz: https://doaj.org/article/35cdeaf8520d46078b684f45c7b6c5d6

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Akademický článek

Functional domains of androgen receptor coactivator p44/Mep50/WDR77and its interaction with Smad1.

Autor: Yirong Li, Liantian Tian, Martin Ligr, Garrett Daniels, Yi Peng, Xinyu Wu, Mandeep Singh, Jianjun Wei, Yongzhao Shao, Herbert Lepor, Ruliang Xu, Zhijie Chang, Zhengxin Wang, Peng Lee

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64663 (2013)

p44/MEP50/WDR77 has been identified as a coactivator of androgen receptor (AR), with distinct growth suppression and promotion function in gender specific endocrine organs and their malignancies. We dissected the functional domains of p44 for protein

Externí odkaz: https://doaj.org/article/a171e214df7948f19f0b7260eaa0733f

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Akademický článek

Bmp7 functions via a polarity mechanism to promote cloacal septation.

Autor: Kun Xu, Xinyu Wu, Ellen Shapiro, Honging Huang, Lixia Zhang, Duane Hickling, Yan Deng, Peng Lee, Juan Li, Herbert Lepor, Irina Grishina

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e29372 (2012)

BackgroundDuring normal development in human and other placental mammals, the embryonic cloacal cavity separates along the axial longitudinal plane to give rise to the urethral system, ventrally, and the rectum, dorsally. Defects in cloacal developme

Externí odkaz: https://doaj.org/article/72f5ea658f0249998899d634e31723ec

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