Zobrazeno 1 - 10
of 151
pro vyhledávání: '"HER2, human epidermal growth factor receptor 2"'
Autor:
Nan Hu, Jun Feng Yin, Ze Ji, Yidong Hong, Puyuan Wu, Baoxiang Bian, Ziyan Song, Rutian Li, Qin Liu, Fenglei Wu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 6, Pp 2158-2173 (2017)
Background/Aims: MicroRNA-21 is an oncogenic miR (oncomiR) frequently elevated in gastric cancer (GC). Overexpression of miR-21 decreases the sensitivity of GC cells to 5-fluorouridine (5-Fu) and trastuzumab, a humanized monoclonal antibody targeting
Externí odkaz:
https://doaj.org/article/9b93d064444f46628a91b7f145a25bf8
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Rugo, Hope S., Lacouture, Mario E., Goncalves, Marcus D., Masharani, Umesh, Aapro, Matti S., O'Shaughnessy, Joyce A.
Publikováno v:
Breast, Vol 61, Iss, Pp 156-167 (2022)
The Breast : Official Journal of the European Society of Mastology
The Breast : Official Journal of the European Society of Mastology
Purpose The oral, α-specific phosphatidylinositol-3-kinase (PI3Kα) inhibitor alpelisib is the first PI3K inhibitor approved for the treatment of advanced breast cancer. As alpelisib is a relatively new therapeutic option, specific guidance and a mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed100c67c3edaa21648be43be27980e
https://doi.org/10.1016/j.breast.2021.12.016
https://doi.org/10.1016/j.breast.2021.12.016
Autor:
Elizabeth W. Thompson, Biniyam G. Demissei, Amanda M. Smith, Priya Brahmbhatt, Jessica Wang, Amy Clark, Angela DeMichele, Vivek Narayan, Payal Shah, Lova Sun, Benedicte Lefebvre, Michael G. Fradley, Joseph R. Carver, W.H. Wilson Tang, Bonnie Ky
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • PON-1 is an HDL-associated cardioprotective enzyme that prevents oxidized-LDL formation and has not previously been studied in cardio-oncology. • To determine the associations between PON-1 and the development of
Highlights • PON-1 is an HDL-associated cardioprotective enzyme that prevents oxidized-LDL formation and has not previously been studied in cardio-oncology. • To determine the associations between PON-1 and the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dadd34a04c67d94c46bd9d5fb98d63f
https://doi.org/10.1016/j.jacbts.2021.10.010
https://doi.org/10.1016/j.jacbts.2021.10.010
Autor:
Alexander Hapfelmeier, Sebastian Foersch, Siranush Karapetyan, Daniel-Christoph Wagner, Katja Steiger, Kristina Schwamborn, Marion Kiechle, Wilko Weichert, Wilfried Roth, Dirk Oettler, Aurelia Noske
Publikováno v:
Breast, Vol 60, Iss, Pp 238-244 (2021)
The Breast : Official Journal of the European Society of Mastology
The Breast : Official Journal of the European Society of Mastology
Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast cancer (TNBC). We compared the analytical concordance and reproducibility of four clinically re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a50b5eac3f8c4ff158e8c3f6dfcb0c
http://www.sciencedirect.com/science/article/pii/S0960977621009851
http://www.sciencedirect.com/science/article/pii/S0960977621009851
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3417-3432 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3417-3432 (2021)
Compounds that selectively modulate multiple targets can provide clinical benefits and are an alternative to traditional highly selective agents for unique targets. High-throughput screening (HTS) for multitarget-directed ligands (MTDLs) using approv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862abd0b2f76391c84b2238b548f152a
https://doi.org/10.1016/j.apsb.2021.02.023
https://doi.org/10.1016/j.apsb.2021.02.023
Autor:
Eleonora De Maio, Gabrielle Selmes, Slimane Zerdoud, Eva Jouve, R. Aziza, Jean-Louis Lacaze, Ciprian Chira, F. Izar, Florence Dalenc, C. Massabeau, Mony Ung, Anne Pradines
Publikováno v:
Breast, Vol 59, Iss, Pp 144-156 (2021)
The Breast : Official Journal of the European Society of Mastology
The Breast : Official Journal of the European Society of Mastology
Does oligometastatic breast cancer (OMBC) deserve a dedicated treatment? Although some authors recommend multidisciplinary management of OMBC with a curative intent, there is no evidence proving this strategy beneficial in the absence of a randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69d7d75860baca5664d0f6f4d7d4a88
http://www.sciencedirect.com/science/article/pii/S0960977621004069
http://www.sciencedirect.com/science/article/pii/S0960977621004069
Autor:
Kenth Gustafsson, Rana Khalife, Konstantin Pildish, Rupali Dabas, Sofia Esteban Serna, Vladimir Kalinovskiy, Noelle Colant, Matas Deveikis, Alexander Van de Steen, Saverio Charalambous, Hasan Mustafa Khan, Stefanie Frank, Clare M. Robinson, Diana A. Catana
Publikováno v:
Synthetic and Systems Biotechnology, Vol 6, Iss 3, Pp 231-241 (2021)
Synthetic and Systems Biotechnology
Synthetic and Systems Biotechnology
The development of Drug Delivery Systems (DDS) has led to increasingly efficient therapies for the treatment and detection of various diseases. DDS use a range of nanoscale delivery platforms produced from polymeric of inorganic materials, such as mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89d5763f69c5fb3ee6055a67c29ad2d
http://www.sciencedirect.com/science/article/pii/S2405805X21000442
http://www.sciencedirect.com/science/article/pii/S2405805X21000442
Autor:
Rosell Murillo, Marina
Als hospitals Vall d'Hebron i Bellvitge s'utilitzen dues marques diferents de tinció de cèl·lules HER2 per diagnosticar pacients amb càncer de mama HER2 positiu, que presenten variacions de color. Disposem d'un conjunt de dades etiquetades de Val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3484::dba86a4e90a7d79dc63702a7e147dbad
https://hdl.handle.net/2117/380696
https://hdl.handle.net/2117/380696
Bilateral breast metastases from small cell lung carcinoma: Case report and review of the literature
Autor:
Emad Allam, Luke Freiburg, John Olivieri, Vijayalakshmi Ananthanarayanan, Shuchi Zinzuwadia, Cheryl Zhang
Publikováno v:
Radiology Case Reports, Vol 16, Iss 7, Pp 1718-1726 (2021)
Radiology Case Reports
Radiology Case Reports
Differentiation of primary versus secondary breast cancer can be difficult, with the relative rarity of the latter representing a diagnostic challenge. Here, we present a case of small cell lung cancer with synchronous bilateral breast metastases in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d430932abb809ba30783896fa77b639
https://doi.org/10.1016/j.radcr.2021.03.056
https://doi.org/10.1016/j.radcr.2021.03.056