Zobrazeno 1 - 10
of 629
pro vyhledávání: '"HENRY S. FRIEDMAN"'
Autor:
Pauline Latzer, Henning Zelba, Florian Battke, Annekathrin Reinhardt, Borong Shao, Oliver Bartsch, Armin Rabsteyn, Johannes Harter, Martin Schulze, Thomas Okech, Alexander Golf, Christina Kyzirakos-Feger, Simone Kayser, Natalia Pieper, Magdalena Feldhahn, Julian Wünsche, Christian Seitz, Dirk Hadaschik, Claus Garbe, Till-Karsten Hauser, Christian la Fougère, Dirk Biskup, Dawn Brooke, David Parker, Uwe M. Martens, Gerald Illerhaus, Deborah T. Blumenthal, Ryan Merrell, Luisa Sánchez Lorenzo, Máté Hidvégi, Paula de Robles, Sied Kebir, William W. Li, Vincent W. Li, Matthew Williams, Alexandra M. Miller, Santosh Kesari, Michael Castro, Annick Desjardins, David M. Ashley, Henry S. Friedman, Patrick Y. Wen, Elisabeth C. Neil, Fabio M. Iwamoto, Bence Sipos, Karsten Geletneky, Lars Zender, Martin Glas, David A. Reardon, Saskia Biskup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Current treatment outcome of patients with glioblastoma (GBM) remains poor. Following standard therapy, recurrence is universal with limited survival. Tumors from 173 GBM patients are analysed for somatic mutations to generate a personalized
Externí odkaz:
https://doaj.org/article/98a07e6f1b4647369483ebef527a8f94
Autor:
Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. Varn, Roel G. Verhaak, Junfei Zhao, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea M. Muscat, Eric S. Lipp, Smita K. Nair, Mustafa Khasraw, Katherine B. Peters, Dina Randazzo, John H. Sampson, Roger E. McLendon, Darell D. Bigner, David M. Ashley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Recurrent glioblastomas (rGBM) have dismal outcomes, but long-term survival has been observed in subsets of patients after immunotherapy. Here the authors report a positive association between low tumor mutation burden, inflammatory gene signatures,
Externí odkaz:
https://doaj.org/article/9b4f7304b8f54613b5f0b6626698e589
Autor:
Jessica W. Lee, John P. Kirkpatrick, Frances McSherry, James E. Herndon, Eric S. Lipp, Annick Desjardins, Dina M. Randazzo, Henry S. Friedman, David M. Ashley, Katherine B. Peters, Margaret O. Johnson
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectivesStandard 6-week and hypofractionated 3-week courses of adjuvant radiation therapy (RT) are both options for older patients with glioblastoma (GBM), but deciding the optimal regimen can be challenging. This analysis explores clinical factors
Externí odkaz:
https://doaj.org/article/fc26f6f0cff541fbbbd72ac16b35f908
Autor:
Bill H. Diplas, Xujun He, Jacqueline A. Brosnan-Cashman, Heng Liu, Lee H. Chen, Zhaohui Wang, Casey J. Moure, Patrick J. Killela, Daniel B. Loriaux, Eric S. Lipp, Paula K. Greer, Rui Yang, Anthony J. Rizzo, Fausto J. Rodriguez, Allan H. Friedman, Henry S. Friedman, Sizhen Wang, Yiping He, Roger E. McLendon, Darell D. Bigner, Yuchen Jiao, Matthew S. Waitkus, Alan K. Meeker, Hai Yan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Glioblastoma can be classified based on IDH and TERT promoter mutations, but ~20% of glioblastoma do not have these mutations (TERT p WT-IDH WT glioblastoma). Here, the authors present a genetic landscape of TERTp WT-IDH WT glioblastoma, identifying
Externí odkaz:
https://doaj.org/article/dd48eac540f1490a9bb31a4f740711ca
Autor:
Anastasie M. Dunn-Pirio, Sarah Woodring, Eric Lipp, James E. Herndon, II, Patrick Healy, Mallika Weant, Dina Randazzo, Annick Desjardins, Henry S. Friedman, Katherine B. Peters
Publikováno v:
Epilepsy and Behavior Case Reports, Vol 10, Iss , Pp 114-117 (2018)
Glioma-associated epilepsy is associated with excessive glutamate signaling. We hypothesized that perampanel, an amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptor antagonist, would treat glioma-related epilepsy. We con
Externí odkaz:
https://doaj.org/article/9b558df933e54c89a08d34abd41958c0
Autor:
Emil Lou, Katherine B. Peters, Ashley L. Sumrall, Annick Desjardins, David A. Reardon, Eric S. Lipp, James E. Herndon II, April Coan, Leighann Bailey, Scott Turner, Henry S. Friedman, James J. Vredenburgh
Publikováno v:
Cancer Medicine, Vol 2, Iss 2, Pp 185-195 (2013)
Abstract Patients with unresectable glioblastomas have a poor prognosis, with median survival of 6–10 months. We conducted a phase II trial of upfront 5‐day temozolomide (TMZ) and bevacizumab (BV) in patients with newly diagnosed unresectable or
Externí odkaz:
https://doaj.org/article/878b6c7f1e0040d09fdb3980bb1eb49e
Autor:
Douglas S. Tyler, Francis Ali-Osman, Henry S. Friedman, John A. Olson, Yasunori Yoshimoto, Jin Soo Yoo, Insuk Sohn, Sin-Ho Jung, Christina K. Augustine
Supplementary Figure 1 from Gene Expression Signatures as a Guide to Treatment Strategies for In-Transit Metastatic Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dda9e30874e7a25b4f4dd3cad880511
https://doi.org/10.1158/1535-7163.22485024.v1
https://doi.org/10.1158/1535-7163.22485024.v1
Autor:
John H. Sampson, Duane A. Mitchell, Gordana Vlahovic, Darell Bigner, Henry S. Friedman, Allan H. Friedman, Roger E. McLendon, Patrick Healy, James E. Herndon, Weihua Xie, Pam Norberg, Robert J. Schmittling, Smita K. Nair, Luis Sanchez-Perez, Gary E. Archer, Elizabeth A. Reap, Kristen A. Batich
supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5fcb114cba3c65477708b3f9a182cf
https://doi.org/10.1158/1078-0432.22467126
https://doi.org/10.1158/1078-0432.22467126
Autor:
Douglas S. Tyler, Francis Ali-Osman, Henry S. Friedman, John A. Olson, Yasunori Yoshimoto, Jin Soo Yoo, Insuk Sohn, Sin-Ho Jung, Christina K. Augustine
Supplementary Figure 4 from Gene Expression Signatures as a Guide to Treatment Strategies for In-Transit Metastatic Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72702db2a95eb0d91fc72bc27cf24fd3
https://doi.org/10.1158/1535-7163.22485015
https://doi.org/10.1158/1535-7163.22485015
Autor:
Douglas S. Tyler, Francis Ali-Osman, Henry S. Friedman, John A. Olson, Yasunori Yoshimoto, Jin Soo Yoo, Insuk Sohn, Sin-Ho Jung, Christina K. Augustine
Supplementary Figure Legends and Methods from Gene Expression Signatures as a Guide to Treatment Strategies for In-Transit Metastatic Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c837ce1fb4862c650d85576a656d0f0
https://doi.org/10.1158/1535-7163.22485012
https://doi.org/10.1158/1535-7163.22485012