Zobrazeno 1 - 10
of 67
pro vyhledávání: '"HENRIK FAGMAN"'
Autor:
Ida Rahmqvist, Enya Engström, Elisabeth Mellström, Raghda R. Ibrahim, Fani Pujol-Calderón, Agnes Dahlstrand Rudin, Anna Ordqvist Redfors, Niki Rostamzadeh, Rita Di Rienzo, Wilma Franssila, Robert Khashan, Moe Xylander, Christin Karlsson, Torben Ek, Daniel Andersson, Tobias Österlund, Jennie Gaarder, Henrik Fagman, Susanne Fransson, Tommy Martinsson, Anders Ståhlberg, Martin Dalin
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-6 (2024)
Abstract Circulating tumor DNA (ctDNA) has shown potential as a non-invasive tumor biomarker in neuroblastoma. Previous studies used generic assays for detection of selected predefined oncogenic variants as markers of ctDNA, which limits the sensitiv
Externí odkaz:
https://doaj.org/article/57f63b45f58b4d5d80b90270eb162760
Autor:
Parmida Ranji, Emma Jonasson, Lisa Andersson, Stefan Filges, Manuel Luna Santamaría, Christoffer Vannas, Soheila Dolatabadi, Anna Gustafsson, Ola Myklebost, Joakim Håkansson, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Myxoid liposarcoma (MLS) displays a distinctive tumor microenvironment and is characterized by the FUS::DDIT3 fusion oncogene, however, the precise functional contributions of these two elements remain enigmatic in tumor developme
Externí odkaz:
https://doaj.org/article/efac96b56a16441ab22d151be2064aa6
Autor:
Se Whee Sammy Park, Susanne Fransson, Fredrik Sundquist, Joachim N. Nilsson, Per Grybäck, Sandra Wessman, Jacob Strömgren, Anna Djos, Henrik Fagman, Helene Sjögren, Kleopatra Georgantzi, Nikolas Herold, Per Kogner, Dan Granberg, Mark N. Gaze, Tommy Martinsson, Kasper Karlsson, Jakob J. E. Stenman
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
In this case report, we present the treatment outcomes of the first patient enrolled in the LuDO-N trial. The patient is a 21-month-old girl diagnosed with high-risk neuroblastoma (NB) and widespread skeletal metastasis. The patient initially underwe
Externí odkaz:
https://doaj.org/article/41ba518bf7834ac3b8d9e8df52b0b021
Autor:
Ella A. Eklund, Ali Mourad, Clotilde Wiel, Sama I. Sayin, Henrik Fagman, Andreas Hallqvist, Volkan I. Sayin
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundKRAS mutation status is a well-established independent prognostic factor in advanced non-small cell lung cancer (NSCLC), yet its role in early-stage disease is unclear. Here, we investigate the prognostic value of combining survival data on
Externí odkaz:
https://doaj.org/article/7f620151d599452782b18578119a2487
Autor:
Sravani Devarakonda, Annika Thorsell, Per Hedenström, Azar Rezapour, Lisen Heden, Sanghita Banerjee, Malin E.V. Johansson, George Birchenough, Amelie Toft Morén, Karin Gustavsson, Viktor Skokic, Victor L. Pettersson, Fei Sjöberg, Marie Kalm, Mohammad Al Masri, Michaela Ekh, Henrik Fagman, Mats Wolving, Rosie Perkins, Rodrigo A. Morales, Francisca Castillo, Eduardo J. Villablanca, Ulf Yrlid, Karin Bergmark, Gunnar Steineck, Cecilia Bull
Publikováno v:
EBioMedicine, Vol 94, Iss , Pp 104691- (2023)
Summary: Background: Radiotherapy is effective in the treatment of cancer but also causes damage to non-cancerous tissue. Pelvic radiotherapy may produce chronic and debilitating bowel symptoms, yet the underlying pathophysiology is still undefined.
Externí odkaz:
https://doaj.org/article/e9705bf6853e4dbbaa1a59fcbdf76691
Autor:
Elin Schoultz, Shawn Liang, Therese Carlsson, Stefan Filges, Anders Ståhlberg, Henrik Fagman, Clotilde Wiel, Volkan Sayin, Mikael Nilsson
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107071- (2023)
Summary: Cells of origin in cancer determine tumor phenotypes, but whether lineage-defining transcription factors might influence tissue specificity of tumorigenesis among organs with similar developmental traits are unknown. We demonstrate here that
Externí odkaz:
https://doaj.org/article/b281298cb2e54671b8aba04ce648649c
Autor:
Malin Lindén, Christoffer Vannas, Tobias Österlund, Lisa Andersson, Ayman Osman, Mandy Escobar, Henrik Fagman, Anders Ståhlberg, Pierre Åman
Publikováno v:
Molecular Oncology, Vol 16, Iss 13, Pp 2470-2495 (2022)
FET fusion oncoproteins containing one of the FET (FUS, EWSR1, TAF15) family proteins juxtaposed to alternative transcription‐factor partners are characteristic of more than 20 types of sarcoma and leukaemia. FET oncoproteins bind to the SWI/SNF ch
Externí odkaz:
https://doaj.org/article/3d44bdb19fd34f31bf7e193e0ead06e7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Accurate pretreatment grading of pancreatic neuroendocrine tumors (PanNETs) is important to guide patient management. We aimed to evaluate endoscopic ultrasound-guided fine needle biopsy sampling (EUS-FNB) for the preoperative diagnosis and
Externí odkaz:
https://doaj.org/article/20ad73a795e5403193b2f766cf1d960a
Autor:
Anna Thulin, Carola Andersson, Elisabeth Werner Rönnerman, Shahin De Lara, Chaido Chamalidou, Arnd Schoenfeld, Anikó Kovács, Henrik Fagman, Fredrik Enlund, Barbro K. Linderholm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract There is limited knowledge of the biology of breast cancer (BC) brain metastasis (BM). We primarily aimed to determine the mutations in BCBM and to compare the mutational pattern with the matched primary breast cancer (BC). Secondary aims we
Externí odkaz:
https://doaj.org/article/6421f4558684416ba1fe18b350461d45
Autor:
Elin Schoultz, Ellen Johansson, Carmen Moccia, Iva Jakubikova, Naveen Ravi, Shawn Liang, Therese Carlsson, Mikael Montelius, Konrad Patyra, Jukka Kero, Kajsa Paulsson, Henrik Fagman, Martin O. Bergo, Mikael Nilsson
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Cancer cells hijack developmental growth mechanisms but whether tissue morphogenesis and architecture modify tumorigenesis is unknown. Here, we characterized a new mouse model of sporadic thyroid carcinogenesis based on inducible expression of BRAF c
Externí odkaz:
https://doaj.org/article/508f6d6970624701985ec7553bd80cdf