Zobrazeno 1 - 10 of 261 pro vyhledávání: '"HEMOGLOBIN SCAVENGER RECEPTOR"'
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Targeting iron metabolism in drug discovery and delivery
Autor: Bart J Crielaard, Twan Lammers, Stefano Rivella
Publikováno v: Nature Reviews Drug Discovery
Iron fulfils a central role in many essential biochemical processes in human physiology, which makes proper processing of iron crucial. Although iron metabolism is subject to relatively strict physiological control, in recent years numerous disorders
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05547e1c6e34c0b20799ad67930e5659
https://doi.org/10.1038/nrd.2016.248
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2
Targeting iron metabolism in drug discovery and delivery
Publikováno v: Nature Reviews Drug Discovery. 16(6):400-423
Iron fulfils a central role in many essential biochemical processes in human physiology; thus, proper processing of iron is crucial. Although iron metabolism is subject to relatively strict physiological control, numerous disorders, such as cancer an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___01423::c1b7611b4cb46b90e4ab3f3d86fa38db
https://doi.org/10.1038/nrd.2016.248
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3
Akademický článek
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5
Abstract WMP106: Soluble CD163 as a Prognostic Marker for Perihematomal Edema Formation and Functional Outcomes in Intracerebral Hemorrhage
Autor: Nancy J. Edwards, Liang Zhu, Davis So, Louise D. McCullough, Meaghan Roy-O’Reilly, Jaroslaw Aronowski, Glenda L Torres
Publikováno v: Stroke. 48
Introduction: Macrophages are the predominant cell capable of removing toxic hemoglobin at sites of tissue injury, and CD163 has been recognized as the hemoglobin scavenger receptor present on the macrophage cell surface. In this study, we explored t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5d95351ce4b8d67843bcc4110b6dd57
https://doi.org/10.1161/str.48.suppl_1.wmp106
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6
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid
Autor: Booiman, Thijs, Wit, Ferdinand W., Maurer, Irma, De Francesco, Davide, Sabin, Caroline A., Harskamp, Agnes M., Prins, Maria, Garagnani, Paolo, Pirazzini, Chiara, Franceschi, Claudio, Fuchs, Dietmar, Gisslén, Magnus, Winston, Alan, Reiss, Peter, Kootstra, Neeltje A., Reiss, P., Wit, F. W. N. M., Schouten, J., Kooij, K. W., van Zoest, R. A., Elsenga, B. C., Janssen, F. R., Heidenrijk, M., Zikkenheiner, W., van der Valk, M., Kootstra, N. A., Booiman, T., Harskamp-Holwerda, A. M., Boeser-Nunnink, B., Maurer, I., Mangas Ruiz, M. M., Girigorie, A. F., Villaudy, J., Frankin, E., Pasternak, A., Berkhout, B., van der Kuyl, T., Portegies, P., Schmand, B. A., Geurtsen, G. J., ter Stege, J. A., Klein Twennaar, M., Majoie, C. B. L. M., Caan, M. W. A., Su, T., Weijer, K., Bisschop, P. H. L. T., Kalsbeek, A., Wezel, M., Visser, I., Ruhé, H. G., Franceschi, C., Garagnani, P., Pirazzini, C., Capri, M., Dall’Olio, F., Chiricolo, M., Salvioli, S., Hoeijmakers, J., Pothof, J., Prins, M., Martens, M., Moll, S., Berkel, J., Totté, M., Kovalev, S., Gisslén, M., Fuchs, D., Zetterberg, H., Winston, A., Underwood, J., McDonald, L., Stott, M., Legg, K., Lovell, A., Erlwein, O., Doyle, N., Kingsley, C., Sharp, D. J., Leech, R., Cole, J. H., Zaheri, S., Hillebregt, M. M. J., Ruijs, Y. M. C., Benschop, D. P., Burger, D., de Graaff-Teulen, M., Guaraldi, G., Bürkle, A., Sindlinger, T., Moreno-Villanueva, M., Keller, A., Sabin, C., de Francesco, D., Libert, C., Dewaele, S.
Publikováno v: Open Forum Infectious Diseases
OPEN FORUM INFECTIOUS DISEASES
Open forum infectious diseases, 4(3). Oxford University Press
Open Forum Infectious Diseases, 4(3). Oxford University Press
Background Increased monocyte activation and intestinal damage have been shown to be predictive for the increased morbidity and mortality observed in treated people living with human immunodeficiency virus (PLHIV). Methods A cross-sectional analysis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4489d6f60bd7ac650f26f062ab881410
https://doi.org/10.1093/ofid/ofx108
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Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats
Autor: Henning Grønbæk, Holger Jon Møller, Søren K. Moestrup, Karen Louise Thomsen, Nils E. Magnusson, Jonas Heilskov Graversen, Hendrik Vilstrup
Publikováno v: Thomsen, K L, Møller, H J, Graversen, J H, Magnusson, N E, Moestrup, S K, Vilstrup, H & Grønbæk, H 2016, ' Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats ', World Journal of Hepatology, vol. 8, no. 17, pp. 726-730 . https://doi.org/10.4254/wjh.v8.i17.726
Thomsen, K L, Møller, H J, Graversen, J H, Magnusson, N E, Moestrup, S K, Vilstrup, H & Grønbæk, H 2016, ' Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats ', World Journal of Hepatology, vol. 8, no. 17, pp. 726-30 . https://doi.org/10.4254/wjh.v8.i17.726
AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats.METHODS: Wistar rats were injected intravenous with either the CD163 targeted dexamethasone-conjugate (0.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de77599dd662d29b064b4edd05f0d07
https://findresearcher.sdu.dk:8443/ws/files/123971287/Anti_CD163_dexamethasone_conjugate_inhibits_the_acute_phase_response_to_lipopolysaccharide_in_rats.pdf
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8
Novel serum biomarkers in carotid artery stenosis
Autor: Clark J. Zeebregts, Linda Hermus, Joost H. N. Schuitemaker, Jan Cees Breek, Esther de Boef, Riemer H. J. A. Slart, René A. Tio
Publikováno v: Clinical biochemistry, 44(16), 1292-1298. PERGAMON-ELSEVIER SCIENCE LTD
Objectives: Serum biomarkers representing inflammatory activity in vulnerable carotid plaques may be used to identify high-risk patients for cerebral ischemic events. We aimed to analyze the relationship between concentrations of four novel biomarker
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b0d742850c611f56dd0937b83c72eb
https://doi.org/10.1016/j.clinbiochem.2011.08.1141
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9
Cardiovascular surgery and organ damage: Time to reconsider the role of hemolysis
Autor: Iris C. Vermeulen Windsant, Sebastiaan J. Hanssen, Wim A. Buurman, Michael J. Jacobs
Publikováno v: Journal of Thoracic and Cardiovascular Surgery, 142(1), 1-11. MOSBY-ELSEVIER
Cardiovascular surgery with cardiopulmonary bypass is associated with postoperative organ injury, which severely affects patient morbidity and mortality. Multiple cardiopulmonary bypass–related mechanisms have been linked to the development of tiss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc20ca9d075a3171a6fa03e0c5c88fe
https://doi.org/10.1016/j.jtcvs.2011.02.012
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10
Akademický článek
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