Zobrazeno 1 - 10
of 729
pro vyhledávání: '"HE Broxmeyer"'
Autor:
Andrew Burgess, Jody Folloder, Lyle D. Broemeling, Saroj Vadhan-Raj, HE Broxmeyer, Nicholas Papadopolous, Shreyaskumar Patel, Carlos E. Bueso-Ramos, Robert S. Benjamin
Publikováno v:
Journal of Clinical Oncology. 21:3158-3167
Purpose: Recombinant human thrombopoietin (rhTPO) increases platelets, and the peak response of rhTPO is delayed and is, therefore, not uniformly effective when administered after chemotherapy. The purpose of this study was to identify an effective s
Autor:
Walter N. Hittelman, I. Mcalister, Nicholas E. Papadopoulos, Saroj Vadhan-Raj, Michael Andreeff, L. Garrison, Douglas E. Williams, Carl Plager, Juan C. Bandres, Robert S. Benjamin, Shreyaskumar Patel, HE Broxmeyer, Andrew Burgess, E. S. Buescher
Publikováno v:
Blood. 86:2098-2105
PIXY321 is a novel fusion protein of recombinant human granulocyte- macrophage colony-stimulating factor and interleukin-3 that exhibits biologic effects of both its parent cytokines in vitro and in preclinical studies. To evaluate the clinical safet
Autor:
Andreas H. Sarris, Douglas Grossman, Albert B. Deisseroth, HE Broxmeyer, William C. Pugh, Nikos Karasavvas, Teresa Esgleyes-Ribot, Madeleine Duvic, Mary Crow
Publikováno v:
Blood. 86:651-658
Human interferon-gamma (IFN-gamma)-inducible protein 10 (IP-10), a C-X- C chemokine, is secreted by IFN-gamma-stimulated keratinocytes and is chemotactic for CD4+ lymphocytes. We therefore investigated its role in the epidermotropism of cutaneous T-c
Autor:
JE Wagner, HE Broxmeyer, RL Byrd, B Zehnbauer, B Schmeckpeper, N Shah, C Griffin, PD Emanuel, KS Zuckerman, S Cooper
Publikováno v:
Blood. 79:1874-1881
The possibility that umbilical cord and placental blood from an HLA- identical sibling might produce stable donor-derived lymphohematopoietic engraftment was tested in a patient with juvenile chronic myelogenous leukemia (JCML). After conditioning wi
Autor:
DE Williams, PJ Morrissey, DY Mochizuki, P de Vries, D Anderson, D Cosman, HS Boswell, S Cooper, KH Grabstein, HE Broxmeyer
Publikováno v:
Blood. 76:906-911
T-cell growth factor P40 was examined for possible effects on murine interleukin-3 (IL-3)-dependent myeloid cell lines and freshly isolated murine bone marrow cells. The results showed that P40 stimulated the proliferation of some IL-3-dependent myel
Autor:
Garland Yee, Saroj Vadhan-Raj, William K. Hoots, HE Broxmeyer, Ann Lemaistre, Jordan U. Gutterman, Stephen Buescher, Josep Lloreta, Li Lu, Sima Jeha, Walter N. Hittelman
Publikováno v:
Blood. 75:858-864
To stimulate granulopoiesis, we gave recombinant human granulocyte- macrophage colony-stimulating factor (GM-CSF; 120 microgram/m2/d) to a patient with congenital neutropenia. The treatment resulted in marked increases in white blood cell counts (max
Autor:
Carlos Bueso-Ramos, John J. Kavanagh, Dennie V. Jones, Saroj Vadhan-Raj, Creighton L. Edwards, Andrzej P. Kudelka, David M. Gershenson, Claire F. Verschraegen, HE Broxmeyer, Mark Ashby, Ralph S. Freedman
Publikováno v:
Annals of internal medicine. 132(5)
Thrombocytopenia is a significant problem in the treatment of cancer.To assess the clinical safety of therapy with recombinant human thrombopoietin (rhTPO) and its ability to ameliorate chemotherapy-induced severe thrombocytopenia.Phase I/II clinical
Autor:
Bs, Youn, Sm, Zhang, Ek, Lee, Dh, Park, He, Broxmeyer, Pm, Murphy, Locati M, James Pease, Kk, Kim, Antol K, Bs, Kwon
Publikováno v:
Europe PubMed Central
A new member of human beta-chemokine cDNA was isolated and named leukotactin-1 (Lkn-1). Lkn-1, along with murine macrophage inflammatory protein-related protein-1 and -2, defines a subgroup of beta-chemokines based on two conserved cysteines in addit
Autor:
Ah, Sarris, Daliani D, Ulmer R, Crow M, He, Broxmeyer, Michael Reiss, Karasavvas N, Ad, Zelenetz, Pugh W, Cabanillas F, Ab, Deisseroth, Duvic M
Publikováno v:
Europe PubMed Central
Human IFN-gamma-inducible protein 10 (IP-10), a C-X-C chemokine secreted by IFN-gamma-stimulated keratinocytes, is chemotactic for normal CD4-positive lymphocytes and inhibits the proliferation of early subsets of normal and of leukemic hemopoietic p
Autor:
Se, Braun, Rs, Mcivor, As, Davidson, Hanna M, Cm, Traycoff, Da, Berebetsky, Gonin R, He, Broxmeyer, Kenneth Cornetta
Publikováno v:
Europe PubMed Central
Mutations in the enzyme dihydrofolate reductase (DHFR) can confer resistance to the inhibitory effects of folate analogs such as methotrexate (Mtx) and trimetrexate (Ttx). Retroviral vectors expressing the DHFR-Arg22 mutants and the newly described D