Zobrazeno 1 - 10
of 50
pro vyhledávání: '"HDL biogenesis"'
Autor:
Xin Bi, Evanthia E. Pashos, Marina Cuchel, Nicholas N. Lyssenko, Mayda Hernandez, Antonino Picataggi, James McParland, Wenli Yang, Ying Liu, Ruilan Yan, Christopher Yu, Stephanie L. DerOhannessian, Michael C. Phillips, Edward E. Morrisey, Stephen A. Duncan, Daniel J. Rader
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 139-145 (2017)
Despite the recognized role of the ATP-binding Cassette Transporter A1 (ABCA1) in high-density lipoprotein (HDL) metabolism, our understanding of ABCA1 deficiency in human hepatocytes is limited. To define the functional effects of human hepatocyte A
Externí odkaz:
https://doaj.org/article/946ab8b7ea644fcfaed179b2dcca84c0
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 941-950 (2012)
The lipidation of apoA-I in liver greatly influences HDL biogenesis and plasma HDL levels by stabilizing the secreted apoA-I. Niacin is the most effective lipid-regulating agent clinically available to raise HDL. This study was undertaken to identify
Externí odkaz:
https://doaj.org/article/93e8fb8fc5c34ba38680dc2a67097473
Autor:
Andreas K. Kateifides, Irina N. Gorshkova, Adelina Duka, Angeliki Chroni, Dimitris Kardassis, Vassilis I. Zannis
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1363-1372 (2011)
Abstract In this study, we investigated the role of positively and negatively charged amino acids within the 89-99 region of apolipoprotein A-I (apoA-I), which are highly conserved in mammals, on plasma lipid homeostasis and the biogenesis of HDL. We
Externí odkaz:
https://doaj.org/article/7ada80ffaa16446c960b9f97839a59e2
Akademický článek
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Publikováno v:
Journal of Biomedical Research
In this review, we focus on the pathway of biogenesis of HDL, the essential role of apoA-I, ATP binding cassette transporter A1 (ABCA1), and lecithin: cholesterol acyltransferase (LCAT) in the formation of plasma HDL; the generation of aberrant forms
Autor:
Stephen A. Duncan, Edward E. Morrisey, Evanthia E. Pashos, Stephanie DerOhannessian, Ying Liu, Antonino Picataggi, Ruilan Yan, James T McParland, Christopher Yu, Daniel J. Rader, Wenli Yang, Xin Bi, Michael C. Phillips, Mayda Hernandez, Nicholas N. Lyssenko, Marina Cuchel
Publikováno v:
EBioMedicine
EBioMedicine, Vol 18, Iss C, Pp 139-145 (2017)
EBioMedicine, Vol 18, Iss C, Pp 139-145 (2017)
Despite the recognized role of the ATP-binding Cassette Transporter A1 (ABCA1) in high-density lipoprotein (HDL) metabolism, our understanding of ABCA1 deficiency in human hepatocytes is limited. To define the functional effects of human hepatocyte A
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 941-950 (2012)
The lipidation of apoA-I in liver greatly influences HDL biogenesis and plasma HDL levels by stabilizing the secreted apoA-I. Niacin is the most effective lipid-regulating agent clinically available to raise HDL. This study was undertaken to identify
Autor:
Man K.S. Lee, Andrew J. Murphy
Publikováno v:
EBioMedicine
EBioMedicine, Vol 18, Iss C, Pp 15-16 (2017)
EBioMedicine, Vol 18, Iss C, Pp 15-16 (2017)
Despite the recognized role of the ATP-binding Cassette Transporter A1 (ABCA1) in high-density lipoprotein (HDL) metabolism, our understanding of ABCA1 deficiency in human hepatocytes is limited. To define the functional effects of human hepatocyte A
Autor:
Vassilis I. Zannis, Irina N. Gorshkova, Angeliki Chroni, Adelina Duka, Andreas K. Kateifides, Dimitris Kardassis
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1363-1372 (2011)
In this study, we investigated the role of positively and negatively charged amino acids within the 89-99 region of apolipoprotein A-I (apoA-I), which are highly conserved in mammals, on plasma lipid homeostasis and the biogenesis of HDL. We previous
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.