Zobrazeno 1 - 10
of 13
pro vyhledávání: '"HDAC6, histone deacetylase 6"'
Autor:
Lu Feng, Kai Zhang, Bo Liu, Tingting Jiang, Liang Ouyang, Guan Wang, Jiamei Li, Shiou Zhu, Junping Pei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3015-3034 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Parkinson's disease (PD), known as one of the most universal neurodegenerative diseases, is a serious threat to the health of the elderly. The current treatment has been demonstrated to relieve symptoms, and the discovery of new small-molecule compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12dab43aca56bfd6a912c2aa71297ff
http://www.sciencedirect.com/science/article/pii/S2211383521000642
http://www.sciencedirect.com/science/article/pii/S2211383521000642
Autor:
Andrew Dickson, Benjamin R. Stromberg, Christine Insinna, Matthew K. Summers, Yosup Rhee, Adrian E. Torres, Debjani Pal, Christopher J. Westlake, Mayank Singh, Amy C. Burrows
Publikováno v:
The Journal of Biological Chemistry
The deubiquitinating enzyme USP37 is known to contribute to timely onset of S phase and progression of mitosis. However, it is not clear if USP37 is required beyond S-phase entry despite expression and activity of USP37 peaking within S phase. We hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eedf7a343128548aa738f8cb79c88d9
http://europepmc.org/articles/PMC8487067
http://europepmc.org/articles/PMC8487067
Autor:
Toshifumi Fukuda, Saho Kato, Shohei Okuda, Mariko Sato, Ryoko Inatome, Shigeru Yanagi, Shun Nagashima
Publikováno v:
The Journal of Biological Chemistry
Radial migration during cortical development is required for formation of the six-layered structure of the mammalian cortex. Defective migration of neurons is linked to several developmental disorders such as autism and schizophrenia. A unique swolle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed46172359dc9ac7681697efc07a5e3
https://pubmed.ncbi.nlm.nih.gov/34298015
https://pubmed.ncbi.nlm.nih.gov/34298015
Autor:
Semir Vranic, Maha Al-Asmakh, Ishita Gupta, Ahmed H. Amarah, Muhammad Umar Sohail, Ala-Eddin Al Moustafa, Khaled E. Elzawawi
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1654-1660 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1654-1660 (2021)
Graphical abstract
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important wi
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fce205d35bae79eb29d825fbfe8d236
https://pubmed.ncbi.nlm.nih.gov/33777332
https://pubmed.ncbi.nlm.nih.gov/33777332
Publikováno v:
Journal of Bone Oncology
Journal of Bone Oncology, Vol 31, Iss, Pp 100403-(2021)
Journal of Bone Oncology, Vol 31, Iss, Pp 100403-(2021)
Highlights • IL-24 can decrease the expression of stem cell markers in CD133+ osteosarcoma CSCs. • IL-24 can inhibit CD133+ osteosarcoma CSCs to form tumors and develop further. • IL-24 inhibits tumorigenicity of osteosarcoma CSCs via inhibitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c099090d80f9f8c1e72cfef3f20d2c8
https://doi.org/10.1016/j.jbo.2021.100403
https://doi.org/10.1016/j.jbo.2021.100403
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 885-886 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is becoming a severe liver disorder worldwide. Autophagy plays a critical role in liver steatosis. However, the role of autophagy in NAFLD remains exclusive and under debate. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1287515fb220d00a7c882d49e29bf5ca
http://www.sciencedirect.com/science/article/pii/S2352345X20301922
http://www.sciencedirect.com/science/article/pii/S2352345X20301922
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 978-986 (2017)
REDOX BIOLOGY(12)
Redox Biology
REDOX BIOLOGY(12)
Redox Biology
Histone deacetylase 6 (HDAC6) likely is important in inflammatory diseases. However, how HDAC6 exerts its effect on inflammatory processes remains unclear. HIV-1 transactivator of transcription (Tat) activates NADPH oxidase resulting in generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8267f6a083589af069e639a42a879b70
http://www.sciencedirect.com/science/article/pii/S2213231717302975
http://www.sciencedirect.com/science/article/pii/S2213231717302975
Autor:
Maria Dominguez, Issidora S. Papassideri, Aimilia D. Sklirou, Marianna Ralli, Ioannis P. Trougakos, Alexios-Leandros Skaltsounis
Publikováno v:
Redox Biology
Redox Biology, Vol 5, Iss, Pp 205-215 (2015)
Redox Biology, Vol 5, Iss, Pp 205-215 (2015)
Despite the fact that several natural products (e.g. crude extracts or purified compounds) have been found to activate cell antioxidant responses and/or delay cellular senescence the effect(s) of small peptides on cell viability and/or modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21d891c4db690600e8c356f78ea8f22
https://pubmed.ncbi.nlm.nih.gov/25974626
https://pubmed.ncbi.nlm.nih.gov/25974626
Autor:
Zhuo B; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Wang X; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Shen Y; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Li J; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Li S; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Li Y; Department of Surgery, Affiliated Xuzhou Children's Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China., Wang R; Department of Ultrasound, The Affiliated Hospital of Xuzhou Medical University, 221006 Xuzhou, Jiangsu, China.
Publikováno v:
Journal of bone oncology [J Bone Oncol] 2021 Nov 03; Vol. 31, pp. 100403. Date of Electronic Publication: 2021 Nov 03 (Print Publication: 2021).
Autor:
Zhang K; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Zhu S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Li J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Jiang T; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Feng L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Pei J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Wang G; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China.; Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041, China., Ouyang L; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China., Liu B; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu 610041, China.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Oct; Vol. 11 (10), pp. 3015-3034. Date of Electronic Publication: 2021 Feb 26.