Zobrazeno 1 - 2
of 2
pro vyhledávání: '"HD, helical domain"'
Autor:
Stevens, Michael, Franke, Barbara, Skorupka, Katarzyna A., Cafiso, David S., Pornillos, Owen, Mayans, Olga, Norman, David G.
Publikováno v:
Journal of Molecular Biology
MuRF1 (TRIM63) is a RING-type E3 ubiquitin ligase with a predicted tripartite TRIM fold. TRIM proteins rely upon the correct placement of an N-terminal RING domain, with respect to C-terminal, specific substrate-binding domains. The TRIM domain organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::00ae6caca3b9842d02f6e93213428bf2
https://pubmed.ncbi.nlm.nih.gov/31125568
https://pubmed.ncbi.nlm.nih.gov/31125568
Publikováno v:
Febs Letters
Highlights • NOD2 SNPs that cause Blau syndrome cluster in two regions of the NACHT. • The ATP/Mg2+ binding pocket cluster are likely to dysregulate ATP hydrolysis. • SNPs in helical domain 1 are predicted to influence receptor autoinhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b0f57f940fda6dbf5e5c02c721cae7
https://doi.org/10.1016/j.febslet.2014.07.029
https://doi.org/10.1016/j.febslet.2014.07.029