Výsledky vyhledávání

Akademický článek

A Novel Small Molecule Inhibits Hepatitis C Virus Propagation in Cell Culture

Autor: Ahmed K. Oraby, Cassandra L. Gardner, Robert F. Needle, Hassan M. Kofahi, Kylie R. Everard, Nathan G. A. Taylor, Suzette G. Rutihinda, Jacqueline P. Barry, Kensuke Hirasawa, Paris E. Georghiou, Rodney S. Russell

Publikováno v: Microbiology Spectrum, Vol 9, Iss 1 (2021)

ABSTRACT Hepatitis C virus (HCV) can cause acute and chronic infection that is associated with considerable liver-related morbidity and mortality. In recent years, there has been a shift in the treatment paradigm with the discovery and approval of ag

Externí odkaz: https://doaj.org/article/46b5e281a5db41a0b9bd7e48ae6024a8

Zobrazit plný text záznamu

Akademický článek

Cellular Cofactors Affecting Hepatitis C Virus Infection and Replication

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2007 Jul . 104(31), 12884-12889.

Externí odkaz: https://www.jstor.org/stable/25436399

Zobrazit plný text záznamu

A Novel Small Molecule Inhibits Hepatitis C Virus Propagation in Cell Culture

Autor: Nathan G. Taylor, Paris E. Georghiou, Jacqueline P Barry, Cassandra L Gardner, Suzette G Rutihinda, Kylie R Everard, Kensuke Hirasawa, Rodney S. Russell, Ahmed K. Oraby, Hassan M. Kofahi, Robert F Needle

Publikováno v: Microbiology Spectrum, Vol 9, Iss 1 (2021)
Microbiology Spectrum

Hepatitis C virus (HCV) can cause acute and chronic infection that is associated with considerable liver-related morbidity and mortality. In recent years, there has been a shift in the treatment paradigm with the discovery and approval of agents that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0293f52b4a934a9ba15959ea8c0dcf52
https://doi.org/10.1128/spectrum.00439-21

Zobrazit plný text záznamu

Approaches, Progress, and Challenges to Hepatitis C Vaccine Development

Autor: Bailey, JR, Barnes, E, Cox, AL

Publikováno v: Gastroenterology

Risk factors for hepatitis C virus (HCV) infection vary, and there were an estimated 1.75 million new cases worldwide in 2015. The World Health Organization aims for a 90% reduction in new HCV infections by 2030. An HCV vaccine would prevent transmis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::42168d6f9100a224824e934ef953c38f
http://europepmc.org/articles/PMC6340767

Zobrazit plný text záznamu

Akademický článek

Chemical Constituents from Flueggea virosa and the Structural Revision of Dehydrochebulic Acid Trimethyl Ester

Autor: Chih-Hua Chao, Ying-Ju Lin, Ju-Chien Cheng, Hui-Chi Huang, Yung-Ju Yeh, Tian-Shung Wu, Syh-Yuan Hwang, Yang-Chang Wu

Publikováno v: Molecules, Vol 21, Iss 9, p 1239 (2016)

In an attempt to study the chemical constituents from the twigs and leaves of Flueggea virosa, a new terpenoid, 9(10→20)-abeo-ent-podocarpane, 3β,10α-dihydroxy-12-methoxy-13- methyl-9(10→20)-abeo-ent-podocarpa-6,8,11,13-tetraene (1), as well as

Externí odkaz: https://doaj.org/article/a1b2dbda4851404a86406c5064b67efd

Zobrazit plný text záznamu

Safety and Efficacy of Avaren-Fc Lectibody Targeting HCV High-Mannose Glycans in a Human Liver Chimeric Mouse Model

Autor: Krystal Teasley Hamorsky, Yoshio Morikawa, Thibaut Vausselin, Jean Dubuisson, Yoshinari Miyata, Matthew Dent, Nobuyuki Matoba

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 2020, ⟨10.1016/j.jcmgh.2020.08.009⟩
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2020, ⟨10.1016/j.jcmgh.2020.08.009⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 185-198 (2021)

Background & Aims Infection with hepatitis C virus (HCV) remains a major cause of morbidity and mortality worldwide despite the recent advent of highly effective direct-acting antivirals. The envelope glycoproteins of HCV are heavily glycosylated wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a77797ed0790198e94d645b7e2d73e5
https://hal.science/hal-02992405/document

Zobrazit plný text záznamu

Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- MiceSummary

Autor: Sonia Bergaya, Michiel C. Mommersteeg, Margaret A. Scull, Charles M. Rice, Jing W. Xiao, Corrine Quirk, Edward A. Fisher, Koen Vercauteren, Ype P. de Jong, Arjun Menon, Ursula Andreo

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 3, Pp 405-417 (2017)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Hepatitis C virus (HCV) is a leading cause of chronic liver diseases and the most common indication for liver transplantation in the United States. HCV particles in the blood of infected patients are characterized by heterogeneous b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542f58cce13163b51bd35d488d8027f6
http://www.sciencedirect.com/science/article/pii/S2352345X17301054

Zobrazit plný text záznamu

Development of Hepatocyte‐like Cell Derived from Human Induced Pluripotent Stem cell as a Host for Clinically Isolated Hepatitis C Virus

Autor: Adisak Wongkajornsilp, Suradej Hongeng, Khanit Sa-ngiamsuntorn

Publikováno v: Current Protocols in Stem Cell Biology

This unit describes protocols to develop hepatocyte‐like cells (HLCs) starting from mesenchymal stem cells (MSCs) as a natural host for hepatitis C virus (HCV). These include the preparation of MSCs from bone marrow, the reprogramming of MSCs into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9152684af987c6e81992f18fa4e2cdc4
http://europepmc.org/articles/PMC7162336

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání