Zobrazeno 1 - 10
of 55
pro vyhledávání: '"HAT, Histone Acetyltransferase"'
Autor:
Verónica Uribe-Etxebarria, Jose Ramon Pineda, Patricia García-Gallastegi, Alice Agliano, Fernando Unda, Gaskon Ibarretxe
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7389 (2023)
The Dental Pulp of permanent human teeth is home to stem cells with remarkable multilineage differentiation ability: human Dental Pulp Stem Cells (DPSCs). These cells display a very notorious expression of pluripotency core factors, and the ability t
Externí odkaz:
https://doaj.org/article/a2773d9fc99d4e909992fe59e6665134
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101207-(2021)
Translational Oncology
Translational Oncology
Highlights • D5D is an independent prognostic factor in cancer. • D5D aggravates cancer progression via mediating AA/PGE2 production from DGLA. • AA/PGE2 promotes cancer progression via regulating the tumor microenvironment. • Inhibition of D
Autor:
Takuya Kajimura, Isao Tamura, Yumiko Doi-Tanaka, Hiroshi Tamura, Yumiko Mihara, Norihiro Sugino, Ryo Maekawa, Shun Sato, Toshiaki Taketani, Yuichiro Shirafuta, Taishi Fujimura, Haruka Takagi
Publikováno v:
The Journal of Biological Chemistry
Human endometrial stromal cells (ESCs) differentiate into decidual cells by the action of progesterone, which is essential for implantation and maintenance of pregnancy. We previously reported that glucose uptake by human ESCs increases during decidu
Publikováno v:
JACC: Basic to Translational Science
Summary Chemical modifications to nucleosomal DNA and histone tails greatly influence transcription of adjacent and distant genes, a mode of gene regulation referred to as epigenetic control. Here, the authors summarize recent findings that have illu
Autor:
Villő Muha, Lydia Teboul, Florence Authier, Sara Johnson, Zsombor Szoke-Kovacs, Daan M. F. van Aalten, Rory J. McCrimmon, Jennifer E. Gallagher, Alison D. McNeilly
Publikováno v:
The Journal of Biological Chemistry
O-GlcNAcylation is an essential post-translational modification that has been implicated in neurodevelopmental and neurodegenerative disorders. O-GlcNAcase (OGA), the sole enzyme catalyzing the removal of O-GlcNAc from proteins, has emerged as a pote
Autor:
Sophie L. Cooke, Carolin A. Müller, Francisco Meirelles Bastos de Oliveira, Conrad A. Nieduszynski, Bárbara Luísa Soares, Robertus A.M. de Bruin
Publikováno v:
The Journal of Biological Chemistry
Saccharomyces cerevisiae exhibits gene expression homeostasis, which is defined as the buffering of transcription levels against changes in DNA copy number during the S phase of the cell cycle. It has been suggested that S. cerevisiae employs an acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bb43f54bb71c409f6a061995fd0d90
https://ueaeprints.uea.ac.uk/id/eprint/87851/
https://ueaeprints.uea.ac.uk/id/eprint/87851/
Autor:
Ryan Dale Marcum, Joseph Hsieh, Maksim Giljen, Emily Justice, Nicolas Daffern, Yongbo Zhang, Ishwar Radhakrishnan
Publikováno v:
The Journal of Biological Chemistry
Chromatin-modifying complexes containing histone deacetylase (HDAC) activities play critical roles in the regulation of gene transcription in eukaryotes. These complexes are thought to lack intrinsic DNA-binding activity, but according to a well-esta
Autor:
Hunter McLeod, Daniel F. Clark, Kimberly R. Shorter, Nuri Smith, Whitnei Smith, Stewart Glenister, Nicole Rogers, Gabriel Castillo, Rahaf Al Sayed
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss, Pp-(2019)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Many diseases are now associated with aberrant epigenetics and gene expression changes. Epigenetics can be modified by factors like diet. One dietary factor, folic acid, is consumed in various forms including supplements, energy drinks, and fortified
Autor:
Monica Raicu, Maya Simionescu, Mihaela-Loredana Antonescu, Ioana Madalina Fenyo, Simona-Adriana Manea, Adrian Manea
Publikováno v:
Redox Biology
Redox Biology, Vol 16, Iss, Pp 332-343 (2018)
Redox Biology, Vol 16, Iss, Pp 332-343 (2018)
Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in diabetes. Epigenetic mechanisms, such as histone acetylation, emerged as important regulators of gene
Autor:
Pranoti Mandrekar
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 713-714 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Ethanol-mediated down-regulation of carnitine palmitoyltransferase-1 (CPT-1A) gene expression plays a major role in the development of hepatic steatosis; however, the underlying mechanisms are not completely elucidated. Tributyrin, a butyrate prodrug