Zobrazeno 1 - 6
of 6
pro vyhledávání: '"HAR, hexaammineruthenium"'
Autor:
Edward Owusu-Ansah, Christian Garcia, Sergey Sosunov, Zoya Niatsetskaya, Anna Stepanova, Vadim Ten, Alexander Galkin, Belem Yoval-Sánchez, Fariha Ansari, Ilka Wittig
Publikováno v:
The Journal of Biological Chemistry
Impairments in mitochondrial energy metabolism have been implicated in human genetic diseases associated with mitochondrial and nuclear DNA mutations, neurodegenerative and cardiovascular disorders, diabetes, and aging. Alteration in mitochondrial co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bb0f4587b2ffb9835213ba93fb65a1
http://europepmc.org/articles/PMC8503622
http://europepmc.org/articles/PMC8503622
Autor:
Philipp Kron, Matteo Mueller, Olivier de Rougemont, David Meierhofer, Philipp Dutkowski, Paolo Muiesan, Anna Stepanova, Xavier Muller, Andrea Schlegel, Alexander Galkin, Pierre-Alain Clavien
Publikováno v:
EBioMedicine
EBioMedicine, Vol 60, Iss, Pp 103014-(2020)
EBioMedicine, Vol 60, Iss, Pp 103014-(2020)
Background Mitochondrial succinate accumulation has been suggested as key event for ischemia reperfusion injury in mice. No specific data are however available on behavior of liver mitochondria during ex situ machine perfusion in clinical transplant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b9e911eda3c09d19bbb520f7b49a76
https://doi.org/10.1016/j.ebiom.2020.103014
https://doi.org/10.1016/j.ebiom.2020.103014
Publikováno v:
Stepanova, A, Valls, A & Galkin, A 2015, ' Effect of monovalent cations on the kinetics of hypoxic conformational change of mitochondrial complex i ', Biochimica et Biophysica Acta-Bioenergetics, vol. 1847, no. 10, pp. 1085-1092 . https://doi.org/10.1016/j.bbabio.2015.05.012
Biochimica et Biophysica Acta
Biochimica et Biophysica Acta
Mitochondrial complex I is a large, membrane-bound enzyme central to energy metabolism, and its dysfunction is implicated in cardiovascular and neurodegenerative diseases. An interesting feature of mammalian complex I is the so-called A/D transition,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7186892e4be76641f9e1bf59523012a
Autor:
Anna, Stepanova, Yevgeniya, Shurubor, Federica, Valsecchi, Giovanni, Manfredi, Alexander, Galkin
Publikováno v:
Biochimica et Biophysica Acta
Mitochondrial Complex II is a key mitochondrial enzyme connecting the tricarboxylic acid (TCA) cycle and the electron transport chain. Studies of complex II are clinically important since new roles for this enzyme have recently emerged in cell signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2320408d45bda73f65b948d81a2b8eb0
https://pubmed.ncbi.nlm.nih.gov/27287543
https://pubmed.ncbi.nlm.nih.gov/27287543
Publikováno v:
Biochemical Journal
The biguanide metformin is widely prescribed for Type II diabetes and has anti-neoplastic activity in laboratory models. Despite evidence that inhibition of mitochondrial respiratory complex I by metformin is the primary cause of its cell-lineage-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e41e2bd4d56d7ebe67ddf4db39dfa4
https://pubmed.ncbi.nlm.nih.gov/25301073
https://pubmed.ncbi.nlm.nih.gov/25301073
Publikováno v:
Biochimica et Biophysica Acta
Babot, M, Birch, A, Labarbuta, P & Galkin, A 2014, ' Characterisation of the active/de-active transition of mitochondrial complex I ', Biochimica et Biophysica Acta-Bioenergetics, vol. 1837, no. 7, pp. 1083–1092 . https://doi.org/10.1016/j.bbabio.2014.02.018
Babot, M, Birch, A, Labarbuta, P & Galkin, A 2014, ' Characterisation of the active/de-active transition of mitochondrial complex I ', Biochimica et Biophysica Acta-Bioenergetics, vol. 1837, no. 7, pp. 1083–1092 . https://doi.org/10.1016/j.bbabio.2014.02.018
Oxidation of NADH in the mitochondrial matrix of aerobic cells is catalysed by mitochondrial complex I. The regulation of this mitochondrial enzyme is not completely understood. An interesting characteristic of complex I from some organisms is the ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36f3e48e8bfd142c4d63b0548d63b96
https://pubmed.ncbi.nlm.nih.gov/24569053
https://pubmed.ncbi.nlm.nih.gov/24569053