Zobrazeno 1 - 10
of 256
pro vyhledávání: '"HAN-CHUNG WU"'
Autor:
Ruei-Min Lu, Hsiang-En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Yin-Shiou Lin, Ching-Hang Liu, Shih-Han Ko, Christian Angelo P. Concio, Yi-Jen Su, Yi-Han Chang, Wen-Shan Li, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-36 (2024)
Abstract Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects. In this regard, lipid nanoparticles h
Externí odkaz:
https://doaj.org/article/0f6655b8145d4bda96e5f7a52141ca40
Autor:
Sushree Shankar Panda, Chi-Chiu Lee, Khamushavalli Geevimaan, Kai-Chi Chen, Shung-Haur Yang, Chia-Ning Shen, Wei-Chun HuangFu, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Background Epithelial cell adhesion molecule (EpCAM) has been widely studied as a tumor antigen due to its expression in varieties of solid tumors. Moreover, the glycoprotein contributes to critical cancer-associated cellular functionalities
Externí odkaz:
https://doaj.org/article/ebea9f77cac94d27b2c3a20d54f81785
Autor:
Chi-Chiu Lee, Chia-Jui Yu, Sushree Shankar Panda, Kai-Chi Chen, Kang-Hao Liang, Wan-Chen Huang, Yu-Shiuan Wang, Pei-Chin Ho, Han-Chung Wu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/c0830c032ec344fd9dbbd7c7a30ef8a5
Autor:
Yu-Shiuan Wang, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Joyce Pei-Yi Yuan, Jui-Ling Tsai, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-35 (2023)
Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a major challenge in realizing this drug class will promise to develop methods for safely delivering the bioactive agents with high efficiency and without activating
Externí odkaz:
https://doaj.org/article/a726cbc007dd4215b7ef1c6581081d8a
Autor:
Chi-Chiu Lee, Chia-Jui Yu, Sushree Shankar Panda, Kai-Chi Chen, Kang-Hao Liang, Wan-Chen Huang, Yu-Shiuan Wang, Pei-Chin Ho, Han-Chung Wu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Epithelial cell adhesion molecule (EpCAM) is known to highly expression and promotes cancer progression in many cancer types, including colorectal cancer. While metastasis is one of the main causes of cancer treatment failure, the
Externí odkaz:
https://doaj.org/article/6494a8b5d11346ee9f7c2cd26962d028
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-13 (2023)
Abstract Background The COVID-19 pandemic continues to pose a significant worldwide threat to human health, as emerging SARS-CoV-2 Omicron variants exhibit resistance to therapeutic antibodies and the ability to evade vaccination-induced antibodies.
Externí odkaz:
https://doaj.org/article/1d7d961b78ef45e7a75d8ce24417a532
Autor:
Pi-Chun Li, Mei-Ying Liao, Ping-Chang Cheng, Jian-Jong Liang, I-Ju Liu, Chien-Yu Chiu, Yi-Ling Lin, Gwong-Jen J Chang, Han-Chung Wu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 3, p e0012031 (2024)
[This corrects the article DOI: 10.1371/journal.pntd.0001636.].
Externí odkaz:
https://doaj.org/article/ac34f7707dea4b759fe77117930c08fb
Autor:
Monika Kumari, Shih-Chieh Su, Kang-Hao Liang, Hsiu-Ting Lin, Yu-Feng Lu, Kai-Chi Chen, Wan-Yu Chen, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-11 (2023)
Abstract Background Sequential infections with SARS-CoV-2 variants such as Alpha, Delta, Omicron and its sublineages may cause high morbidity, so it is necessary to develop vaccines that can protect against both wild-type (WT) virus and its variants.
Externí odkaz:
https://doaj.org/article/2150241d8ed84f008d3b9efa8e55f62c
Autor:
Monika Kumari, Kang-Hao Liang, Shih-Chieh Su, Hsiu-Ting Lin, Yu-Feng Lu, Ming-Jane Wu, Wan-Yu Chen, Han-Chung Wu
Publikováno v:
Vaccines, Vol 12, Iss 7, p 714 (2024)
SARS-CoV-2 new waves are primarily caused by changes to the spike protein (S), which can substantially decrease the efficacy of vaccines. Therefore, we tested several multivalent mRNA-LNP vaccines, targeting the full-length S proteins of different va
Externí odkaz:
https://doaj.org/article/065a807d43ca4f63bb9b8eec1855c9e7
Autor:
Shih-Han Ko, Wan-Yu Chen, Shih-Chieh Su, Hsiu-Ting Lin, Feng-Yi Ke, Kang-Hao Liang, Fu-Fei Hsu, Monika Kumari, Chi-Yu Fu, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background The variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) harbor diverse spike (S) protein sequences, which can greatly influence the efficacies of therapeutics. Therefore, it would be of great value to develop
Externí odkaz:
https://doaj.org/article/738750f514c14a22a2f66f17d012271e