Zobrazeno 1 - 10
of 158
pro vyhledávání: '"HAN KIAT HO"'
Autor:
Ding Quan Ng, Ivy Cheng, Claire Wang, Chia Jie Tan, Yi Long Toh, Yong Qin Koh, Yu Ke, Koon Mian Foo, Raymond J. Chan, Han Kiat Ho, Lita Chew, Mohamad Farid bin Harunal Rashid, Alexandre Chan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Brain-derived neurotrophic factor (BDNF) improves cognitive function by stimulating neurogenesis and neuroplasticity. We hypothesize that higher plasma BDNF levels are protective against cognitive toxicity among adolescent and young adult ca
Externí odkaz:
https://doaj.org/article/819eb62ff5274c3c82b4d5c569d70482
Autor:
Magdiel Inggrid Setyawati, Qin Wang, Nengyi Ni, Jie Kai Tee, Katsuhiko Ariga, Pu Chun Ke, Han Kiat Ho, Yucai Wang, David Tai Leong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Delivering cancer therapeutics to tumors necessitates their escape from the surrounding blood vessels. Tumor vasculatures are not always sufficiently leaky. Herein, we engineer therapeutically competent leakage of therapeutics from tumor vas
Externí odkaz:
https://doaj.org/article/e413c0de6cc74a60977fa23041387bc9
Autor:
Alexandre Chan, Ivy Cheng, Claire Wang, Chia Jie Tan, Yi Long Toh, Ding Quan Ng, Yong Qin Koh, Hanzhang Zhou, Koon Mian Foo, Raymond Javan Chan, Han Kiat Ho, Lita Chew, Mohamad Farid, Ian Tannock
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4821-4831 (2023)
Abstract Background There is little information about cancer‐related cognitive impairment (CRCI) in adolescent and young adults (AYA, 15–39 years old) due to its rare incidence. Here, we present the pre‐treatment (before chemotherapy or radioth
Externí odkaz:
https://doaj.org/article/c1d406691b044e288bf975b823f30c15
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background and Aims: Various publications suggested that there is an association between CYP7A1 single nucleotide polymorphisms (SNP) and a reduced response to statin therapy, but the results were inconsistent. This study aimed to collectively review
Externí odkaz:
https://doaj.org/article/72ea7b34c17247adbadefe8751c420c6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Moderate hypothermia (32 °C) has been previously shown to ameliorate drug-induced liver injuries in vitro. However, there are concerns regarding its clinical relevance as it remains a challenge to perform selective liver cooling in a non-in
Externí odkaz:
https://doaj.org/article/d3730dcb0cf048a1bedb4709e89923ea
Autor:
Yong Qin Koh, Yu Ang Desmond Sin, Hengyang Justin Rong, Teng Hui Sean Chua, Si-Han Sherman Ho, Han Kiat Ho
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10131- (2022)
Carbohydrate digestibility is a key determinant for elevated postprandial hyperglycemia (PPHG). Apart from dietary restrictions, one of the strategies to reduce PPHG is to limit the activity of carbohydrate digestive enzymes within the gastrointestin
Externí odkaz:
https://doaj.org/article/80ff5e6a40dd4e3fb4d4817718173898
Publikováno v:
The Asia Pacific Scholar, Vol 6, Iss 3, Pp 118-120 (2021)
Externí odkaz:
https://doaj.org/article/28175de240164f5ca84de65cdde9b3c0
Autor:
Ning Yi Yap, Wei Sheng Loo, Huang Fang Zheng, Quan Ming Tan, Tze Kiat Tan, Leona Yan Peng Quek, Chia Jie Tan, Yi Long Toh, Chiu Chin Ng, Seng Kok Ang, Veronique Kiak Mien Tan, Han Kiat Ho, Lita Chew, Kiley Wei-Jen Loh, Tira Jing Ying Tan, Alexandre Chan
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Cancer-related fatigue (CRF) is a debilitating condition which commonly affects cancer survivors. The management of CRF remains a challenge due to the lack of effective pharmacological interventions. Traditional Chinese medicine (
Externí odkaz:
https://doaj.org/article/532e7fe4c4134b1d8fbfb265829ecf01
Autor:
Yong Qin Koh, Ding Quan Ng, Chiu Chin Ng, Adrian Boey, Meng Wei, Siu Kwan Sze, Han Kiat Ho, Munjal Acharya, Charles L Limoli, Alexandre Chan
Publikováno v:
Biomarker Insights, Vol 16 (2021)
Cognitive impairment due to cancer and its therapy is a major concern among cancer patients and survivors. Extracellular vesicle (EVs) composition altered by cancer and chemotherapy may affect neurological processes such as neuroplasticity, potential
Externí odkaz:
https://doaj.org/article/1bb526e96ff1467d865ea7375d3f84f0
Publikováno v:
Dose-Response, Vol 18 (2020)
Acetaminophen (APAP) overdose accounts for the highest incidence of acute liver failure, despite the availability of an antidote i.e. N-acetylcysteine. This calls for alternative strategies to manage APAP-induced liver injury (AILI). Therapeutic hypo
Externí odkaz:
https://doaj.org/article/72dfd0e0b1c649d492d526037d2756ae