Zobrazeno 1 - 10
of 298
pro vyhledávání: '"HAKAN BAGCI"'
Autor:
Hannah J. Gleneadie, Beatriz Fernandez-Ruiz, Alessandro Sardini, Mathew Van de Pette, Andrew Dimond, Rab K. Prinjha, James McGinty, Paul M. W. French, Hakan Bagci, Matthias Merkenschlager, Amanda G. Fisher
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
With the long-term goal of finding therapeutic options for Duchenne muscular dystrophy, a mouse model enabling simultaneous visualisation of Dmd and Utrn is described and inhibitors of PRC2 and ERK1/2 identified to increase utrophin expression.
Externí odkaz:
https://doaj.org/article/c6e9b4a0f39e4abeb7c2631bde5a7ad8
Autor:
Omar Alkhazragi, Ming Dong, Liang Chen, Meiwei Kong, Georgian Melinte, Dong Liang, Tien Khee Ng, Junping Zhang, Hakan Bagci, Boon S. Ooi
Publikováno v:
APL Photonics, Vol 8, Iss 8, Pp 086108-086108-10 (2023)
Though necessary and advantageous in many fields, the high coherence of lasers is detrimental to their performance in certain applications, including illumination, imaging, and projection. This is due to the formation of coherence artifacts, commonly
Externí odkaz:
https://doaj.org/article/c7d6208ddc3f472e80968183eec27f10
Publikováno v:
IEEE Access, Vol 9, Pp 54811-54819 (2021)
An efficient nonlinear contrast source inversion scheme for electromagnetic imaging of sparse two-dimensional investigation domains is proposed. To avoid generating a sequence of linear sparse optimization problems, the non-linearity is directly tack
Externí odkaz:
https://doaj.org/article/e13dfc29ee2a47df8aa557da346de80e
Publikováno v:
IEEE Access, Vol 9, Pp 73695-73702 (2021)
Fractional calculus has tremendous potential in modeling the evolution of complex systems including those with memory. Indeed, fractional-order models are more accurate in approximating non-locally distributed dynamics with short- or long-term memory
Externí odkaz:
https://doaj.org/article/80134175f8754b618a41eb6448e59dd6
Publikováno v:
IEEE Access, Vol 8, Pp 7531-7538 (2020)
Isolated conductors appear in various electrostatic problems. In simulations, an equipotential condition with an undefined/floating potential value is enforced on the surface of isolated conductors. In this work, a numerical scheme making use of the
Externí odkaz:
https://doaj.org/article/3b5039a83a0a4ffba8f2a1e251416458
Autor:
Liang Chen, Hakan Bagci
Publikováno v:
IEEE Access, Vol 8, Pp 16203-16215 (2020)
Design of modern nanostructured semiconductor devices often calls for simulation tools capable of modeling arbitrarily-shaped multiscale geometries. In this work, to this end, a discontinuous Galerkin (DG) method-based framework is developed to simul
Externí odkaz:
https://doaj.org/article/b8d1b81de9644e28b3dbce30c53547e8
Autor:
Aslihan Kartci, Agamyrat Agambayev, Mohamed Farhat, Norbert Herencsar, Lubomir Brancik, Hakan Bagci, Khaled N. Salama
Publikováno v:
IEEE Access, Vol 7, Pp 80233-80246 (2019)
This study proposes a new approach for the optimization of phase and magnitude responses of fractional-order capacitive and inductive elements based on the mixed integer-order genetic algorithm (GA), over a bandwidth of four-decade, and operating up
Externí odkaz:
https://doaj.org/article/ead297e53c1a4f2fafd46ec56d5fae39
Publikováno v:
Biosensors, Vol 12, Iss 4, p 215 (2022)
Two-dimensional concentric asymmetric microelectrodes play a crucial role in developing sensitive and specific biological assays using fluid micromixing generated by alternating current electrohydrodynamics (ac-EHD). This paper reports the design, si
Externí odkaz:
https://doaj.org/article/992dd7be74ff4a7c8ab286f8a93ff168
Autor:
Irene Cantone, Hakan Bagci, Dirk Dormann, Gopuraja Dharmalingam, Tatyana Nesterova, Neil Brockdorff, Claire Rougeulle, Celine Vallot, Edith Heard, Ronan Chaligne, Matthias Merkenschlager, Amanda G. Fisher
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Reactivation of the inactive X chromosome (Xi) has modelled epigenetic reprogramming in mouse. Here, by using cell fusion between human female fibroblasts and mouse embryonic stem cells, the authors show a complex hierarchy of epigenetic changes that
Externí odkaz:
https://doaj.org/article/4e0f58511c414c589feb938c38b79712
Autor:
David Landeira, Hakan Bagci, Andrzej R. Malinowski, Karen E. Brown, Jorge Soza-Ried, Amelie Feytout, Zoe Webster, Elodie Ndjetehe, Irene Cantone, Helena G. Asenjo, Neil Brockdorff, Thomas Carroll, Matthias Merkenschlager, Amanda G. Fisher
Publikováno v:
Cell Reports, Vol 12, Iss 4, Pp 573-586 (2015)
Jarid2 is part of the Polycomb Repressor complex 2 (PRC2) responsible for genome-wide H3K27me3 deposition. Unlike other PRC2-deficient embryonic stem cells (ESCs), however, Jarid2-deficient ESCs show a severe differentiation block, altered colony mor
Externí odkaz:
https://doaj.org/article/cd6c76d224db4aafbca8014a4874a97c