Zobrazeno 1 - 10
of 1 384
pro vyhledávání: '"H3K4"'
Publikováno v:
Journal of Advanced Research, Vol 62, Iss , Pp 47-57 (2024)
Introduction: Penicillium expansum is a harmful plant fungal pathogen that causes blue mold disease and produces mycotoxin patulin, leading to huge economic losses and food safety hazard. Set1 associated complex Set1/COMPASS deposits the methylation
Externí odkaz:
https://doaj.org/article/46ad33f6f59843049bc8db4c9e076e12
Autor:
Junsoo Oh, Shinae Park, Jueun Kim, Soojin Yeom, Ji Min Lee, Eun-Jin Lee, Yong-Joon Cho, Jung-Shin Lee
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Histone H3K4 tri-methylation (H3K4me3) catalyzed by Set1/COMPASS, is a prominent epigenetic mark found in promoter-proximal regions of actively transcribed genes. H3K4me3 relies on prior monoubiquitination at the histone H2B (H2Bu
Externí odkaz:
https://doaj.org/article/a975e1dfbf7f4e6fa9e9e1105286fc73
Autor:
Salomão Dória Jorge, Young-In Chi, Jose Lizarraga Mazaba, Neshatul Haque, Jessica Wagenknecht, Brian C. Smith, Brian F. Volkman, Angela J. Mathison, Gwen Lomberk, Michael T. Zimmermann, Raul Urrutia
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Kleefstra Syndrome type 2 (KLEFS-2) is a genetic, neurodevelopmental disorder characterized by intellectual disability, infantile hypotonia, severe expressive language delay, and characteristic facial appearance, with a spectrum of othe
Externí odkaz:
https://doaj.org/article/42efcd3dc5964c3fa2bcda5d1e79ac6b
Autor:
Seung-Hye Choi, Ali Yousefian-Jazi, Seung Jae Hyeon, Phuong Thi Thanh Nguyen, Jiyeon Chu, Sojung Kim, Suhyun Kim, Hannah L. Ryu, Neil W. Kowall, Hoon Ryu, Junghee Lee
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive paralysis due to motor neuron degeneration. It has been proposed that epigenetic modification and transcriptional dysregulation
Externí odkaz:
https://doaj.org/article/ce1f5c250fe848ecbc04308709d14522
Autor:
Koen M. A. Dreijerink, Ezgi Ozyerli-Goknar, Stefanie Koidl, Ewoud J. van der Lelij, Priscilla van den Heuvel, Jeffrey J. Kooijman, Martin L. Biniossek, Kees W. Rodenburg, Sheikh Nizamuddin, H. T. Marc Timmers
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-16 (2022)
Abstract Background Loss-of-function mutations of the multiple endocrine neoplasia type 1 (MEN1) gene are causal to the MEN1 tumor syndrome, but they are also commonly found in sporadic pancreatic neuroendocrine tumors and other types of cancers. The
Externí odkaz:
https://doaj.org/article/6dc511dabcc44e2ba09886a49c36dce6
Autor:
Zhe Liu, Weijing Hu, Yali Qin, Li Sun, Lingyun Jing, Manman Lu, Yan Li, Jing Qu, Zhenhua Yang
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 2, Pp 151295- (2023)
Histone H3 lysine 4 (H3K4) methylation is generally recognized as a prominent marker of gene activation. While Set1/Mll complexes are major methyltransferases that are responsible for H3K4 methylation, the mechanism of how these complexes are recruit
Externí odkaz:
https://doaj.org/article/00ddbd7dd33c48e28607f44ee5269ec1
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas L Young, Michael-Christopher Keogh, Brian D Strahl
Publikováno v:
eLife, Vol 12 (2023)
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://doaj.org/article/4578fc571e78426c9ad347f2e09aa9c9
Autor:
Ning‐hua Mei, Shi‐meng Guo, Qi Zhou, Yi‐ran Zhang, Xiao‐zhao Liu, Ying Yin, Ximiao He, Jing Yang, Tai‐lang Yin, Li‐quan Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Significantly decreased H3K4 methylation in oocytes from aged mice indicates the important roles of H3K4 methylation in female reproduction. However, how H3K4 methylation regulates oocyte development remains largely unexplored. In this study
Externí odkaz:
https://doaj.org/article/065bb0620036479691131bf444ac6f21
Publikováno v:
Cancer Management and Research, Vol Volume 15, Pp 625-626 (2023)
Wu X, Xu Q, Chen P, et al. Cancer Manag Res. 2019;11:8125–8133. We, the Editor and Publisher of Cancer Management and Therapy are retracting the published article. Concerns were raised following the authors request to correct images in Figure 5. It
Externí odkaz:
https://doaj.org/article/c4a59b69d6504f13aba3f77a73ff7d99
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.