Zobrazeno 1 - 10
of 32
pro vyhledávání: '"H2A.B"'
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 993 (2024)
Epigenetic regulation, which is characterized by reversible and heritable genetic alterations without changing DNA sequences, has recently been increasingly studied in diseases. Histone variant regulation is an essential component of epigenetic regul
Externí odkaz:
https://doaj.org/article/777d977eed84485b990d3ed49937eac3
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background H2A.B, the most divergent histone variant of H2A, can significantly modulate nucleosome and chromatin structures. However, the related structural details and the underlying mechanism remain elusive to date. In this work, we built
Externí odkaz:
https://doaj.org/article/d7335c69a829448bbf9755c313d76ca1
Akademický článek
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Autor:
Nur Diana Anuar, Sebastian Kurscheid, Matt Field, Lei Zhang, Edward Rebar, Philip Gregory, Thierry Buchou, Josephine Bowles, Peter Koopman, David J. Tremethick, Tatiana A. Soboleva
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Altering the biochemical makeup of chromatin by the incorporation of histone variants during development represents a key mechanism in regulating gene expression. The histone variant H2A.B, H2A.B.3 in mice, appeared late in evolut
Externí odkaz:
https://doaj.org/article/1ac2215f698d4f058171c99f12cd4416
Publikováno v:
Cells, Vol 9, Iss 4, p 867 (2020)
The dynamic packaging of DNA into chromatin regulates all aspects of genome function by altering the accessibility of DNA and by providing docking pads to proteins that copy, repair and express the genome. Different epigenetic-based mechanisms have b
Externí odkaz:
https://doaj.org/article/09e9afdcd4a541558a810ac246766a6d
Akademický článek
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Autor:
Zhang, H.
Publikováno v:
None
Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations. H2A.B is one of the most divergent H2A variants and is involved in important cellular functions, such as transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::25f424bda107ec0755f662638ba09d11
http://hdl.handle.net/1887/135944
http://hdl.handle.net/1887/135944
Publikováno v:
Epigenetics & Chromatin
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-14 (2020)
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-14 (2020)
Background H2A.B, the most divergent histone variant of H2A, can significantly modulate nucleosome and chromatin structures. However, the related structural details and the underlying mechanism remain elusive to date. In this work, we built atomic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e62f476cdf3267a0018a879cc4ba0e6
http://europepmc.org/articles/PMC7362417
http://europepmc.org/articles/PMC7362417
Publikováno v:
Cells
Cells, Vol 9, Iss 867, p 867 (2020)
Cells, Vol 9, Iss 867, p 867 (2020)
The dynamic packaging of DNA into chromatin regulates all aspects of genome function by altering the accessibility of DNA and by providing docking pads to proteins that copy, repair and express the genome. Different epigenetic-based mechanisms have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9915f9394d0acbfc57dfca24db5933f
http://europepmc.org/articles/PMC7226823
http://europepmc.org/articles/PMC7226823
Autor:
Peter Koopman, David J. Tremethick, Tatiana A. Soboleva, Lei Zhang, Josephine Bowles, Matthew A. Field, Sebastian Kurscheid, Philip D. Gregory, Thierry Buchou, Nur Diana Anuar, Edward J. Rebar
Publikováno v:
Genome Biology
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Background Altering the biochemical makeup of chromatin by the incorporation of histone variants during development represents a key mechanism in regulating gene expression. The histone variant H2A.B, H2A.B.3 in mice, appeared late in evolution and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4872eeeacad5a58e6968c19b2714c595
https://doi.org/10.1186/s13059-019-1633-3
https://doi.org/10.1186/s13059-019-1633-3