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Autor:
J.T. Lutgerink, J.G. Westra, E. Kriek, M.J. BIeeker, W.J. van Dijk, J. H. Van Boom, H. F. Brugghe, H.den van Elst, J. C. Klein, A.J.M. Bems, G.A.der van Marel
Publikováno v:
Nucleic Acids Research. 18:4131-4137
We developed a simian virus 40 based shuttle vector system to study the molecular consequences of distinct carcinogen-induced DNA lesions in human cells. To establish the mutagenicity of O4-ethylthymine adducts, oligonucleotides carrying a single O4-