Zobrazeno 1 - 10
of 81
pro vyhledávání: '"H.U. Aeschbacher"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 269:193-200
A ternary antioxidant vitamin mix consisting of ascorbic acid, alpha-tocopherol and lecithin as well as a rosemary extract with carnosic acid and carnosol as the two major active ingredients were shown to exhibit strong antimutagenic effects in Ames
Autor:
H.U. Aeschbacher, Robert J. Turesky
Publikováno v:
Mutation Research/Genetic Toxicology. 259:235-250
Heterocyclic aromatic amines are bacterial mutagens which also induce DNA damage in mammalian cells. Damage has been demonstrated using a number of endpoints, including gene mutation, chromosome aberrations, sister-chromatid exchange, DNA-strand brea
Autor:
E. Jaccaud, H.U. Aeschbacher
Publikováno v:
Food and Chemical Toxicology. 28:633-637
Oral administration of coffee at doses ranging from 150 mg to 1 g per kg body weight significantly decreased endogenously formed nitrosourea-mediated DNA damage in bone marrow as well as in colon epithelial cells in mice that had simultaneously recei
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 59:301-304
Publikováno v:
Toxicology Letters. 7:71-77
Pregnant Sprague—Dawley rats were given caffeine at 1.0,0.5 and 0.25 g/kg diet during gestation and lactation. At birth, half of the pups from control and treated rats at each dose level were exchanged and cross fostered. Two litters were produced
Publikováno v:
Food and Chemical Toxicology. 27:227-232
About 40 coffee aroma constituents belonging to the classes of dicarbonyls, sulphur-containing compounds, furfuryls, N-heterocyclics and others were systematically evaluated in three Ames tester strains. Only aliphatic dicarbonyl compounds showed not
Autor:
H.U. Aeschbacher
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 164:109-115
It has previously been shown that the inbred mouse strain MS/Ae was more sensitive in the micronucleus test to several mutagenic agents than outbred mice. To elucidate the possible influence of inbreeding, several inbred strains including MS/Ae, AKR,
Publikováno v:
Food and Chemical Toxicology. 22:803-807
Administration of a single oral dose of instant coffee to Chinese hamsters at levels up to 2.5 g/kg body weight did not increase the frequency of sister chromatid exchanges. Furthermore, five consecutive daily oral doses of instant coffee given to Sw
Autor:
H.U. Aeschbacher, C. Chappuis
Publikováno v:
Mutation Research/Genetic Toxicology. 89:161-177
The urine of human coffee drinkers who ingested 12 g of instant coffee per day, during 4 days in a first experiment or 12 g within 2 h in a second experiment, was fractionated by XAD-2 column chromatography. The non-polar urine fractions so obtained
Publikováno v:
Journal of Food Safety. 8:167-177
A bacterial mutagenicity test is described for the evaluation of unextracted food products containing otherwise high levels of interfering histidine. The system involves the use of Ames tester strains preincubated with food samples followed by centri