Zobrazeno 1 - 10
of 54
pro vyhledávání: '"H.P. Gelbke"'
Autor:
Margino Steemans, D.B. Stedman, Els Adriaens, S. Schwengberg, F. van der Water, Joan Albert Vericat, H. J. Ahr, Cristian Pellizzer, Philippe Vanparys, Horst Spielmann, Michael Schwarz, M. Verwei, P. Marx-Stoelting, Aldert H. Piersma, U. Reuter, B. Schenk, Bernward Garthoff, Susanne Bremer, H.P. Gelbke, Andrea Seiler, Michaela Weimer, Vera Rogiers
Publikováno v:
Alternatives to Laboratory Animals. 37:313-328
The new European chemicals policy for the Registration, Evaluation, Authorisation and Restriction of Chemicals (the REACH system), requires the routine toxicological testing of chemicals produced in volumes of more than one tonne per year, in order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cbdf464db5e60acec19865f0113fab
https://doi.org/10.1177/026119290903700314
https://doi.org/10.1177/026119290903700314
Publikováno v:
Toxicology. 205(1-2)
The question whether (man-made or natural) chemical substances may have an adverse effect on the endocrine system has gained high visibility in the public as well as in the scientific community. This relates to possible effects on the environment as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a50f891c583f9e9973fe318efb46a5c
https://pubmed.ncbi.nlm.nih.gov/15458786
https://pubmed.ncbi.nlm.nih.gov/15458786
Autor:
H.P. Gelbke, R. Knuppen
Publikováno v:
Journal of Steroid Biochemistry. 7:457-463
The excretion pattern of different 2-hydroxyoestrogen monomethyl ethers (2-methoxyoestrone, 2-hydroxyoestrone 3-methyl ether, 2-methoxyoestradiol, 2-hydroxyoestradiol 3-methyl ether and the sum of the isomeric monomethyl ethers of 2-hydroxyoestriol)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530586e3d6ba1cddda920295578c10e6
https://doi.org/10.1016/0022-4731(76)90112-6
https://doi.org/10.1016/0022-4731(76)90112-6
Autor:
R. Knuppen, H.P. Gelbke
Publikováno v:
Journal of Steroid Biochemistry. 5:1-7
2-Hydroxyoestriol was isolated from human late-pregnancy urine and quantitatively determined by g.l.c. The purification procedure involved two chromatographic steps on silica gel columns and two paper Chromatographic separations using ascorbic acid i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797f973d337d2027a955a9067943c8f8
https://doi.org/10.1016/0022-4731(74)90020-x
https://doi.org/10.1016/0022-4731(74)90020-x
Publikováno v:
Journal of Steroid Biochemistry. 6:1187-1191
2-Hydroxyoestradiol was identified in human pregnancy urine and quantitatively determined. The isolation procedure involved four Chromatographie purification steps of 2-hydroxyoestradiol on ascorbic acid impregnated stationary phases and the formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a2f4e4dd72510345f5c56918d96be0
https://doi.org/10.1016/0022-4731(75)90101-6
https://doi.org/10.1016/0022-4731(75)90101-6
Autor:
H.P. Gelbke, R. Knuppen
Publikováno v:
Steroids. 21:689-702
For stabilisation 2-hydroxyestrone and 2-hydroxyestradiol-17β are converted to their phenazine derivatives by oxidation with sodium metaperiodate to the 2,3-quinones and subsequent condensation with o-phenylenediamine. The structures of this new cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4410d7ca3f1de119daadd8cff893bf5e
https://doi.org/10.1016/0039-128x(73)90136-0
https://doi.org/10.1016/0039-128x(73)90136-0
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 40:406-408
A double isotope derivative determination technique was developed to investigate the excretion of 2-hydroxyestrone in human menstrual cycle. The method is highly specific, accurate and precise within the range of 0.2–20 nmol 2-hydroxyestrone/20 ml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23320bc44378b1febd5b8beee8857c68
https://doi.org/10.1210/jcem-40-3-406
https://doi.org/10.1210/jcem-40-3-406
Autor:
G. Stubenrauch, H.P. Gelbke
Publikováno v:
Journal of chromatography. 120(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37109ba62d7fa7bbd98cba5ba56cad32
https://pubmed.ncbi.nlm.nih.gov/1270552
https://pubmed.ncbi.nlm.nih.gov/1270552
Publikováno v:
Steroids. 21(2)
The preparation of 2-hydroxyestrone, 2-hydroxyestradiol-17, 4-hydroxyestrone and 4-hydroxyestradiol-17β by a simple one-step chemical reaction, treatment with potassium nitrosodisulfonate, is described. The structures of the products were establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3568a1e1f357e3df3a42606b8978f35c
https://pubmed.ncbi.nlm.nih.gov/4689745
https://pubmed.ncbi.nlm.nih.gov/4689745
Autor:
H.P. Gelbke, R. Knuppen
Publikováno v:
Journal of chromatography. 71(3)
Methods are described for the chromatography of the very labile 2-hydroxyestradiol-17β on paper, thin layers and columns without oxidative decomposition. This is accomplished by impregnating the stationary phases with ascorbic acid as reductant, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac36a3c316f26d9885eb709748adab85
https://pubmed.ncbi.nlm.nih.gov/4342285
https://pubmed.ncbi.nlm.nih.gov/4342285