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Diagnostic challenges in monitoring and evaluating annual ivermectin (Mectizan®) treatment intervention strategy to determine onchocerciasis elimination status

Autor: H.O. Osue, H.I. Inabo, S.E. Yakubu, P.A. Audu

Publikováno v: Sokoto Journal of Medical Laboratory Science; Vol. 7 No. 3 (2022); 85-101

Ability to accurately detect an active infection depends largely on the high accuracy (sensitivity and specificity) of a diagnostic test. There is no single diagnostic tool that meets the criteria of been simple, measurable, accurate, repeatable and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407f3ad3236ce6ec8cfbce5e4425bb72
https://www.ajol.info/index.php/sokjmls/article/view/236208

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Comparing antibody responses to Onchocerca volvulus and non-parasite antigens in placebo-controlled and ivermectin-treated onchocerciasis patients

Autor: F.N.C Enwezor, B. Jones, F Engelbrecht, A. Abiose, B.T. Idowu, H. Edeghere, A. Cassel-Brown, H.O Osue

Publikováno v: African Journal of Clinical and Experimental Microbiology; Vol 18, No 1 (2017); 42-48

Serum antibodies to parasite-specific and non-parasite antigens were evaluated using enzyme-linked immunosorbent assay (ELISA). Out of the 470 sera collected, 409 were from residents of an onchocerciasis hyper-endemic area, 55 non-endemic and 6 Europ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f794ef5ae059e448ddc2229addf84b
https://doi.org/10.4314/ajcem.v18i1.6

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Active transmission of Trypanosoma brucei gambiense Dutton, 1902 sleeping sickness in Abraka, Delta State, Nigeria

Autor: A Aderemi, F.A.G Lawani, H.O Osue, I Saddiq, P Simmaro, V Lejon, A Diara

Publikováno v: Science World Journal. 3

Active surveillance of Human African trypanosomiasis (HAT) or sleeping sickness was undertaken in 3 agrarian villages in Ethiope East Local Government Area of Delta State, Nigeria. Card Agglutination Trypanosomiasis Test (CATT) was used qualitatively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af61fcca56f93d2f070fa3f6bd6d3d8
https://doi.org/10.4314/swj.v3i2.51777

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Sensitivity of some Immunoglobulin G class and subclass antibodies to adult Onchocerca volvulus SDS-extracted antigens

Autor: H.O Osue, H.U Edeghere, F Engelbrecht, I.E Odama, M Galadima

Publikováno v: Science World Journal. 3

Indirect sandwich enzyme-linked immunosorbent assay (ELISA) was used to measure serum antibody responses in onchocerciasis patients. Apparently, IgG antibody class was more sensitive than IgG1, IgG3 and IgG4 responses to Onchocerca volvulus adult wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fadc50f0f5f61003d486b882cfba2e9a
https://doi.org/10.4314/swj.v3i2.51773

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Onchocerca volvulus: Characterization of the clinical status of onchocerciasis patients using antibodies reactivity in enzyme-linked immunosorbent assays

Autor: H.O Osue, H. Edeghere, E Engelbrecht, L Odama, M Galadima

Publikováno v: Nigerian Journal of Parasitology; Vol 30, No 1 (2009)

Serum anti-bodies, IgA, IgG class and subclasses (excluding IgG2) and IgM responses to crude sodium-duodecyl sulphate (SDS) extract of Onchocerca volvulus female adult worms, were tested with indirect enzyme-linked immunosorbent assay (ELISA). Antige

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150d458780d17479e2583fa90bdd5c92
https://doi.org/10.4314/njpar.v30i1.43977

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Quantitative Changes In Antibodies Against Onchocercal Native Antigens Two Months Postivermectin Treatment Of Onchocerciasis Patients

Autor: H. Edeghere, F Engelbrecht, M Galadima, L Odama, H.O Osue

Publikováno v: African Journal of Clinical and Experimental Microbiology; Vol 10, No 1 (2009); 26-37

Serum antibodies to Onchocerca volvulus native sodium duodecylsulphate slat extracted antigens and epitopes recognized by three monoclonal antibodies designated Cam8, Cam22, and Cam28 were measured using indirect (sandwich) and competitive enzyme-lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed711079c5226d8edefaaa61274436f9
https://doi.org/10.4314/ajcem.v10i1.7504

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Effects of infection with Trypanosoma brucei brucei on different trimesters of pregnancy in ewes

Autor: H.O. Osue, O. Falope, J. N. Abenga, Elizabeth Elhassan, F.A.G. Lawani, Henry U. Edeghere

Publikováno v: Veterinary parasitology. 43(3-4)

The effects of Trypanosoma brucei brucei infection during the first, second or third trimesters of pregnancy in 13 ewes were studied. All infected ewes were anaemic with the anaemia being most severe, moderate and least in ewes infected in the second

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183c189e1c4c70feacb89395df186e5e
https://pubmed.ncbi.nlm.nih.gov/1413452

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