Zobrazeno 1 - 10
of 64
pro vyhledávání: '"H.J. van der Linde"'
Autor:
M Traebert, Christopher Habermann, Heike Schauerte, Irwin, T Dinklo, Anke Rosch, Katja Hempel, C van Amsterdam, H.J. van der Linde, A Delaunois, H Lorenz, Cara Heers, M Deurinck, G Teuns, Herbert M. Himmel, T M Eriksson Faelker
Publikováno v:
Journal of pharmacological and toxicological methods. 99
Introduction Irwin/FOB testing is routinely conducted to investigate the neurofunctional integrity of laboratory animals during preclinical development of new drugs, however, the study design frequently varies to meet specific needs. Representatives
Autor:
Mohamed Kreir, I. Van den Wyngaert, S. Versweyveld, B. Van Deuren, H.J. van der Linde, Hua Rong Lu, Greet Teuns, A. De Bondt, David J. Gallacher
Publikováno v:
Toxicology and applied pharmacology. 346
Drug-induced seizures contribute to the high attrition rate of pharmaceutical compounds in development. The assessment of drug-induced seizure liability generally occurs in later phases of development using low throughput and intensive in vivo assays
Publikováno v:
British Journal of Pharmacology. 161:1444-1454
BACKGROUND AND PURPOSE In cardiovascular pharmacology, electrical and mechanical events can be distinguished, and the phrase ‘electro-mechanical window’ (EMw) describes the temporal difference between these events. We studied whether changes in E
Akademický článek
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Publikováno v:
British Journal of Pharmacology. 154:1474-1481
Background and purpose: Body core temperature (Tc) changes affect the QT interval, but correction for this has not been systematically investigated. It may be important to correct QT intervals for drug-induced changes in Tc.
Publikováno v:
Informatorium voor Voeding en Diëtetiek ISBN: 9789036805070
In dit hoofdstuk wordt ingegaan op het voedingsbeleid bij acute pancreatitis, chronische pancreatitis en het pancreascarcinoom. Respectievelijk worden de anatomie, fysiologie, pathologie, epidemiologie, etiologie, klinische verschijnselen en diagnost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860fdb0dadf971d36d350df6c65fa9d8
https://doi.org/10.1007/978-90-368-0508-7_7
https://doi.org/10.1007/978-90-368-0508-7_7
Autor:
W.H. Drinkenburg, H.J. van der Linde, B. Van Deuren, Yves Somers, Ard Teisman, David J. Gallacher
Publikováno v:
Journal of pharmacological and toxicological methods. 63(1)
Introduction The purpose of this study was to explore the integration of electroencephalographical (EEG) measurements into the fentanyl/etomidate-anaesthetised Beagle (FEAB) model in order to detect burst suppression and/or seizure development caused
Autor:
H.J. van der Linde, R.W.E. van der Wal
Publikováno v:
Educational and Training Technology International. 28:188-195
SUMMARY With regard to the problems related to inadequately qualified black teachers of physical science in South Africa, the Research Institute for Education Planning has started to develop computer software in physical science which may be used by
Autor:
M. Peeters, B. Van Deuren, H.J. van der Linde, K. Van Ammel, H.R. Lu, W. Loots, A. Van de Water, David J. Gallacher
Publikováno v:
Journal of pharmacological and toxicological methods. 52(1)
Instability of QT duration is a marker to predict Torsade de Pointes (TdP) associated with both congenital and drug-induced long QT syndrome. We describe a new method for the quantification of instability of repolarization.Female, adult beagle dogs a
Autor:
David J. Gallacher, Annik Vanlommel, B. Van Deuren, Rob Towart, Ard Teisman, Sigrid Janssens, Frank Cools, Yves Somers, H.J. van der Linde, J. Verrelst
Publikováno v:
Heart. 97:e2-e2
The electro-mechanical window (EMw) is a recently proposed biomarker describing the temporal difference between electrical and mechanical events in beating hearts and is a precursor to identify Torsade de Pointes (TdP) risk in the anaesthetised dog.1