Zobrazeno 1 - 10
of 47
pro vyhledávání: '"H.A.G. Niederländer"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 74:133-140
A screening method for trace analysis of potentially genotoxic alkylating compounds has been developed using butyl 1-(pyridin-4-yl) piperidine 4-carboxylate (BPPC) as a new, selective pre-column derivatization reagent for their subsequent analysis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9220eea3bda3a2aad0d0f83792772e
https://doi.org/10.1016/j.jpba.2012.10.004
https://doi.org/10.1016/j.jpba.2012.10.004
Publikováno v:
Journal of Chromatography A, 1149(2), 169-177. ELSEVIER SCIENCE BV
Proteomics samples often contain both abundant proteins and low-level proteins and peptides. Highly abundant proteins can mask and/or bind those of lower abundance and thereby hinder their analysis. In particular, we were concerned with samples conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c076b03f6e7aaf21ffe80d4c603c16
https://doi.org/10.1016/j.chroma.2007.02.118
https://doi.org/10.1016/j.chroma.2007.02.118
Autor:
Laurent Rieux, Paul M. van Midwoud, Rainer Bischoff, H.A.G. Niederländer, Elisabeth Verpoorte
Publikováno v:
Journal of Proteome Research, 6(2), 781-791. NLM (Medline)
Poor repeatability of peak areas is a problem frequently encountered in peptide analysis with nanoLiquid Chromatography coupled on-line with Mass Spectrometry (nanoLC-MS). As a result, quantitative analysis will be seriously hampered unless the obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171a4aaed6d2ff54cdbfd7230378693d
https://doi.org/10.1021/pr0604099
https://doi.org/10.1021/pr0604099
Publikováno v:
Journal of Chromatography A, 1120(1-2), 165-172. ELSEVIER SCIENCE BV
Proteomic studies have stimulated the development of novel stationary phases in miniaturised chromatographic columns that permit high linear flow velocities and exhibit high resolving power. In this work, a 50-mu m reversed-phase silica-based monolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927f9a3955b06ef4056410f27d0e5d0a
https://doi.org/10.1016/j.chroma.2006.01.038
https://doi.org/10.1016/j.chroma.2006.01.038
Publikováno v:
Journal of Separation Science. 28(14):1628-1641
In recent years, proteomics has been a subject of intense research. The complexity of proteomics samples has fostered technological developments. One of these addresses the need for more efficient and faster separations. Monolithic columns prepared f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36ae7774d0d4f5cb2ce42a9416b227c
https://hdl.handle.net/11370/c05dd724-5ec9-4392-b5a6-7903577d566c
https://hdl.handle.net/11370/c05dd724-5ec9-4392-b5a6-7903577d566c
Autor:
Patty Mulder, Rainer Bischoff, Sabeth Verpoorte, H.A.G. Niederländer, Laurent Rieux, J.R. Freije, W. Werkman
Publikováno v:
Journal of Proteome Research, 4(5), 1805-1813. NLM (Medline)
Tryptic digestion followed by identification using mass spectrometry is an important step in many proteomic studies. Here, we describe the preparation of immobilized, acetylated trypsin for enhanced digestion efficacy in integrated protein analysis p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d0b49d04076b3caad26479eba482ed
https://doi.org/10.1021/pr050142y
https://doi.org/10.1021/pr050142y
Autor:
Rokus A. de Zeeuw, H.A.G. Niederländer, Gerhardus J. de Jong, Mischa W. J. van Hout, Vincent Jas
Publikováno v:
Journal of Separation Science, 26(17), 1563-1568
Solid-phase microextraction (SPME) has been directly coupled to an ion-trap mass spectrometer (MS) for the determination of the model compound lidocaine in urine, hereby applying MS/MS [fragmentation of [M + H](+) (m/z 235) to a fragment with m/z 86]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1470750c54a26d7786ceb5eae22b8564
https://doi.org/10.1002/jssc.200301567
https://doi.org/10.1002/jssc.200301567
Autor:
R.A. de Zeeuw, H.A.G. Niederländer, A. P. Bruins, G.J. de Jong, Corry M. Hofland, M.W.J van Hout
Publikováno v:
Journal of Chromatography B. 794:185-192
Solid-phase extraction (SPE) was directly coupled to mass spectrometry (MS) to assess the feasibility of the system for the rapid determination of prednisolone in serum. A C18 stationary phase allowed washing of the cartridge with 25% methanol. Eluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd3c841802bfe9feeec22330c3d8e2ef
https://doi.org/10.1016/s1570-0232(03)00395-7
https://doi.org/10.1016/s1570-0232(03)00395-7
Publikováno v:
Rapid Communications in Mass Spectrometry. 17:245-250
Ion suppression effects were observed during the determination of clenbuterol in urine with solid-phase extraction/multiple-stage ion-trap mass spectrometry (SPE/MS(3)), despite the use of atmospheric pressure chemical ionisation. During SPE, a polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86bc21b2a04b259bff395e3bd46601e
https://doi.org/10.1002/rcm.908
https://doi.org/10.1002/rcm.908
Publikováno v:
Analytica chimica acta. 874
A CE-MS method has been developed to detect trace levels of potentially genotoxic alkyl halides. After derivatization of the target components with 4-dimethylaminopyridine (DMAP) or butyl 1-(pyridinyl-4yl) piperidine 4-carboxylate (BPPC), the nativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0a021373da4c074a4e2d5eeb56179c
https://pubmed.ncbi.nlm.nih.gov/25910449
https://pubmed.ncbi.nlm.nih.gov/25910449