Zobrazeno 1 - 10
of 55
pro vyhledávání: '"H.A. Sancovich"'
Publikováno v:
International Journal of Toxicology. 27:455-465
These studies try to elucidate why isocoproporphyrin appears in hexachlorobenzene-poisoned rats’ feces. Chronic exposure of hexachlorobenzene to rats produces an experimental model for human porphyria cutanea tarda. After 8 weeks of treatment, rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedb131fa977ae098315a78be54b8266
https://doi.org/10.1080/10915810802657002
https://doi.org/10.1080/10915810802657002
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1074:172-177
In the rat liver, the microsomal content of cytochrome P -450 decreased by 50% after triiodothyronine (T 3 ) administration. The molecular basis for the decreased cytochrome P -450 levels was investigated. The activities of the enzymes involved in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfec4876f948d938f57f59518972e6d
https://doi.org/10.1016/0304-4165(91)90057-n
https://doi.org/10.1016/0304-4165(91)90057-n
Autor:
Y. E. Sopena De Kracoff, H. Fukuda, L. E. Inigo, Alcira M. Del C. Batlle, A. M. Ferramola de Sancovich, H.A. Sancovich, S. R. Paredes
Publikováno v:
Journal of Enzyme Inhibition. 3:295-302
Photoxidation with methylene blue and rose bengal and chemical modification by diethylpyrocarbonate of pig liver 5-aminolevulinic acid dehydratase produced strong inactivation of the enzyme which was concentration dependent.Loss of enzyme activity by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacf4183f8822f820d5401a76c499ba0
https://doi.org/10.3109/14756369009030378
https://doi.org/10.3109/14756369009030378
Publikováno v:
Journal of inorganic biochemistry. 99(2)
ALA-D (EC 4.2.1.24) is the first cytosolic enzyme in the haem metabolic pathway. Some metals compete with its major cofactor Zn(2+), modifying both enzyme structure and function. Our purpose was to contribute to the understanding of the biochemical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073cfe81ac99a8dd86e898af218d3c34
https://pubmed.ncbi.nlm.nih.gov/15621272
https://pubmed.ncbi.nlm.nih.gov/15621272
Autor:
Andrea Randi, Rodolfo A Kölliker Frers, Fernanda Spinelli, Andrea Loaiza, Ana Maria Ferramola de Sancovich, H.A. Sancovich, Diana Kleiman de Pisarev
Publikováno v:
Biochemical pharmacology. 65(9)
In the present study, the effects of hexachlorobenzene (HCB) on epidermal growth factor receptor (EGFR) content of liver microsomes and plasma membrane, and on EGFR-tyrosine kinase activity in the microsomal fraction were investigated. In addition, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa7df9acf877b1fc3e6315f56752233
https://pubmed.ncbi.nlm.nih.gov/12732362
https://pubmed.ncbi.nlm.nih.gov/12732362
Publikováno v:
British poultry science. 43(2)
1. Chick embryos of 7, 9, 11, 12, 13, 14, 15, 17 and 19 d of embryonic development were examined to determine the activities of 5-aminolevulinic dehydratase (ALA-D, EC 4.2.1.24) and porphobilinogen deaminase (PBG-D, EC 4.3.1.8). 2. Liver and yolk sac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac290cfc0bbacd01fc00ac944753660
https://pubmed.ncbi.nlm.nih.gov/12047082
https://pubmed.ncbi.nlm.nih.gov/12047082
Publikováno v:
The international journal of biochemistrycell biology. 27(12)
5-Aminolevulinic acid dehydratase catalyses the self condensation between two molecules of 5-aminolevulinic acid, via a Schiff base, in which a lysine residue at its active site is proposed to be involved. The aim of the work was to further clarify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93111049ad400cee383afb117e7074a8
https://pubmed.ncbi.nlm.nih.gov/8581829
https://pubmed.ncbi.nlm.nih.gov/8581829
Publikováno v:
Journal of endocrinological investigation. 18(4)
The functional thyroid status of hexachlorobenzene (HCB)-treated rats was studied. HCB caused a depletion of serum thyroxine (T4 ), but did not change L-3,5,3’-triiodothyronine (T3) levels in serum of rats. The activities of the thyroid regulated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5f44864cf60588e8a4994b4439c66d
https://pubmed.ncbi.nlm.nih.gov/7560808
https://pubmed.ncbi.nlm.nih.gov/7560808
Publikováno v:
Journal of Endocrinological Investigation. 12:767-772
The effect of hexachlorobenzene (HCB) (1 g/kg bw) administration for 4 weeks, on thyroxine (T4) and triiodothyronine (T3) metabolism was studied in Wistar rats. The effect on serum binding of T4 has also been studied. Animals were injected with a tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65420220fcdd5fe1e31b16e0cc29eede
https://doi.org/10.1007/bf03350056
https://doi.org/10.1007/bf03350056
Publikováno v:
Bioorganic Chemistry. 9:71-120
Four heptacarboxylic, six hexacarboxylic, and four pentacarboxylic porphyrins related to uroporphyrin-III by decarboxylation of one, two, or three of the acetic acid side chains have been synthesised as their methyl esters by application of the MacDo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a88b3de7f10ebb59cc35b558207fd04
https://doi.org/10.1016/0045-2068(80)90034-6
https://doi.org/10.1016/0045-2068(80)90034-6