Výsledky vyhledávání - "H.-J. Heberling"

Different immunophenotype and autoantibody production by peripheral blood and thyroid-derived lymphocytes in patients with Graves' disease

Autor: H.-J. Heberling, I. Lehmann, G. Aust

Publikováno v: Experimental and Clinical Endocrinology & Diabetes. 104:50-58

Direct multi-colour flow cytometric analysis was employed in patients with Graves' disease (n = 10) to determine the immunophenotype in peripheral blood lymphocytes (PBL) at the time of diagnosis without treatment (PBLw) and prior to operation (PBLp)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba39ba7003353179319b1b708e3fc5f5
https://doi.org/10.1055/s-0029-1211422

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Lack of Association of Nonautoimmune Hyperfunctioning Thyroid Disorders and a Germline Polymorphism of Codon 727 of the Human Thyrotropin Receptor in a European Caucasian Population1

Autor: Tina Mühlberg, Werner Joba, H.-J. Heberling, Armin E. Heufelder, Kathrin Herrmann, M. Kirchberger

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 85:2640-2643

Constitutively activating mutations of the human TSH receptor (hTSHR) gene have been implicated as a major cause of hyperfunctioning nonautoimmune thyroid disease. However, significant geographic differences in the prevalence of these mutations have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c52901950fdd51a4f8b8b72082c45ad
https://doi.org/10.1210/jcem.85.8.6704

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Lack of association of nonautoimmune hyperfunctioning thyroid disorders and a germline polymorphism of codon 727 of the human thyrotropin receptor in a European Caucasian population

Autor: T, Mühlberg, K, Herrmann, W, Joba, M, Kirchberger, H J, Heberling, A E, Heufelder

Publikováno v: The Journal of clinical endocrinology and metabolism. 85(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afdfd4b41bfa1e19dac2597caccd2234
https://pubmed.ncbi.nlm.nih.gov/10946858

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Interleukin-1 receptor antagonist ribonucleic acid and protein expression by cultured Graves' and normal orbital fibroblasts is differentially modulated by dexamethasone and irradiation

Autor: T, Mühlberg, W, Joba, C, Spitzweg, H D, Schworm, H J, Heberling, A E, Heufelder

Publikováno v: The Journal of clinical endocrinology and metabolism. 85(2)

Recent data have indicated that orbital fibroblasts (OF) can be stimulated to produce marked quantities of interleukin-1 receptor antagonist (IL-1RA), a powerful inhibitor of the proinflammatory activities of interleukin-1 in the orbital tissues in G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e1341f163e302dba1af84c3de9e2e15
https://pubmed.ncbi.nlm.nih.gov/10690884

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Lack of association of Graves' disease with the A2 allele of the interleukin-1 receptor antagonist gene in a white European population

Autor: M. Kirchberger, Christine Spitzweg, Armin E. Heufelder, F Herrmann, T Muhlberg, H.-J. Heberling

Publikováno v: European journal of endocrinology. 138(6)

OBJECTIVE: To assess whether the A2-type IL-1RA polymorphism is associated with Graves' disease and Graves' ophthalmopathy. Several reports have described a genetic association between the A2 allele of the interleukin-1 receptor antagonist (IL-1RA) g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13c9a00faeba70566e928884ac71081
https://pubmed.ncbi.nlm.nih.gov/9678537

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Detection and modulation of interleukin-1 receptor antagonist messenger ribonucleic acid and immunoreactivity in Graves' orbital fibroblasts

Autor: T, Mühlberg, H J, Heberling, W, Joba, H D, Schworm, A E, Heufelder

Publikováno v: Investigative ophthalmologyvisual science. 38(5)

To analyze the expression and regulation of intracellular and soluble interleukin-1 (IL-1) receptor antagonist (IL-1RA) in orbital fibroblasts and to determine whether a disbalance between IL-1 receptor agonist and antagonist may promote IL-1 mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9274e32f84212b94f8ef0e514158e27b
https://pubmed.ncbi.nlm.nih.gov/9112998

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[Results of lithium treatment in severe hyperthyroidism]

Autor: C, Wünsch, H J, Heberling

Publikováno v: Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten. 44(1)

Up to the present time lithium therapy is under discussion in patients with severe, particularly of contrast remedy induced hyperthyroidism. The aim of our presentation was to investigate if the short term combined methimazole-lithium therapy in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6986693fad020dfc6b81975f063199e8
https://pubmed.ncbi.nlm.nih.gov/6423365

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