Zobrazeno 1 - 10
of 65
pro vyhledávání: '"H.-J. Barrach"'
Publikováno v:
Agents and Actions. 41:193-199
Cartilage destruction is a characteristic feature of osteoarthritis. Treatment with certain nonsteroidal anti-inflammatory drugs could exacerbate cartilage destruction by impairing the synthesis of cartilage matrix proteins, type II collagen and prot
Publikováno v:
Immunological Investigations. 23:85-98
Immunoassays are used for the specific measurement of type II collagen, a major cartilage protein, which is lost in osteoarthritic joints. Poor immunogenicity and species dependent immune response to type II collagen make it difficult to obtain speci
Publikováno v:
Journal of Immunological Methods. 159:53-62
This paper describes the development of quantitative immunoassays utilizing mouse monoclonal antibodies which are monospecific to type II collagen. The monoclonal antibodies were characterized and tested extensively for reactivity against a panel of
Publikováno v:
Annals of the New York Academy of Sciences. 878
Publikováno v:
The Journal of pharmacy and pharmacology. 48(7)
Propagated Swarm rat chondrosarcoma cells, rabbit chrondrocytes (from articular cartilage of knee, shoulder and hip joints), and bovine nasal cartilage explant cultures were studied. Type II collagen (CII) and its peptide fragments were quantitated i
Publikováno v:
Clinical orthopaedics and related research. (314)
One of the major unresolved questions in trauma repair concerns the degree of step-off that can be accepted in a joint surface. In answer to this question, a new rabbit model of femoral step-off was developed. Osteoarthrotic changes in cartilage and
Publikováno v:
Anatomy and embryology. 185(4)
Brachypod (bpH/bpH), an autosomal mutation in mice, is characterized by a shortening of the long bones and paws, and a delay or absence of ossification in some of the distal limb elements. The present study represents a detailed description of the br
Publikováno v:
Journal of immunological methods. 140(2)
Specific type II collagen monoclonal antibodies are needed for the quantification of articular cartilage collagen. In this study we produced and characterized 29 type II collagen monoclonal antibodies. Hybridomas were generated from mice immunized wi
Autor:
Stephen I. Rennard, Vincent C. Hascall, Koji Kimata, H. J. Barrach, J H Kimura, Eugene J M A Thonar
Publikováno v:
Journal of Biological Chemistry. 257:3819-3826
Publikováno v:
Cells Tissues Organs. 126:68-72
Elastin was isolated from the human aorta by three different extraction methods. Immunization was carried out in sheep. The presence of antibody against each elastin preparation in the sheep sera was confirmed by immunofluorescence. However, antiseru