Zobrazeno 1 - 10
of 427
pro vyhledávání: '"H.-D. Klenk"'
Autor:
H.-D. Klenk, Rudolf Rott
Publikováno v:
Zentralblatt für Veterinärmedizin Reihe B. 20:509-521
Zusammenfassung Eine Analyse der bei der Vermehrung des Virus der Klassischen Geflugelpest in embryonalen Huhnerzellen gebildeten Proteine ergab, das das an der Virusausenhulle lokalisierte Hamagglutinin uber Vorlaufer synthetisiert wird. Ein Polypep
Publikováno v:
Voprosy virusologii. 58(4)
The propagation of the pandemic influenza virus H1N1 in cultures of bronchial (Calu-3) and intestinal (Caco-2) differentiated epithelial cells of human origin was studied. The canine epithelial cell lines, MDCK-H and MDCK-2, were comparatively tested
Autor:
H D, Klenk
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 56(1)
Wild aquatic birds are natural hosts for a large variety of influenza A viruses. Occasionally, viruses are transmitted from this reservoir to other species, such as chickens, pigs, and man, and may then cause devastating outbreaks in domestic poultry
Autor:
H.-D. Klenk, R. Ohuchi, W. Schäfer, K. Radsak, W. Garten, Martin Vey, William J. Britt, B. Reis
Publikováno v:
Virology. 206(1):746-749
Inhibition of endoproteolytic cleavage of glycoprotein B (gB; gpUL55) of human cytomegalovirus was achieved by treatmentof infected fibroblasts with decanoyl peptidyl chloromethyl ketone (decRVKR-CMK), which inhibits the action of cellular subtilisin
Publikováno v:
Voprosy virusologii. 56(4)
The authors studied a possible role of the caspase cleavage motif located in the nucleoprotein (NP) of pandemic influenza virus H1N1 in the regulation of viral virulence properties. A reverse genetics method was used to obtain chimeric seasonal-like
Autor:
O P, Zhirnov, H D, Klenk
Publikováno v:
Voprosy virusologii. 55(2)
Segment NS in all human influenza A viruses and in the part of avian and animal ones was found to contain an additional (beside NS1 and NEP) long open reading frame (ORF) enabling to code a polypeptide of 18-26 kD in different strains. This ORF, in c
Publikováno v:
Voprosy virusologii. 53(6)
A reverse genetics approach was applied to generate variants of avian influenza virus A/FPV/Ro/34 (H7N1) containing mutations in the caspase cleavage sites of NP and M2 proteins. Mutation Gly16 --Asp in avian virus NP made this protein (NPgd) sensiti
Publikováno v:
Biochemistry. Biokhimiia. 68(9)
Replication of human influenza A viruses and proteolytic cleavage of the viral glycoprotein HA0 --HA1/2 were studied in passaged cultures of epithelial cells of the mucosal membrane of human large intestine (CACO-2 line), dog kidney cells (MDCK), and
Publikováno v:
Biochemistry. Biokhimiia. 67(5)
In this investigation, an ability of influenza A virus M1 matrix protein to bind intracellular caspases, the key enzymes of cell apoptosis, has been examined. Protein-protein binding on polystyrene plates and polyvinyl pyrrolidone membrane was employ
Publikováno v:
Voprosy virusologii. 44(6)
Antibodies specific to the N-terminal 34-aminoacid peptide of the major nucleocapsid protein NP of human influenza A viruses were obtained. The NP proteolytic cleavage occurring in infected cells late in infection has been demonstrated using this ant