Zobrazeno 1 - 10
of 124
pro vyhledávání: '"H.-B. Schüttler"'
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196435 (2018)
A major challenge in systems biology is to infer the parameters of regulatory networks that operate in a noisy environment, such as in a single cell. In a stochastic regime it is hard to distinguish noise from the real signal and to infer the noise c
Externí odkaz:
https://doaj.org/article/a560143ae0d640928aeb70c625df2b9c
Akademický článek
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Autor:
Lingyun Wu, Zhaojie Deng, Samuel V. Arsenault, Michael T. Judge, H.-B. Schüttler, Brooke Hull, Jonathan Arnold, Cristian Caranica, Xiao Qiu, Jia Hwei Cheong, Ahmad Al-Omari, James F. Griffith, Leidong Mao, Carmen Rodriguez
Publikováno v:
IEEE Access, Vol 7, Pp 49403-49417 (2019)
Using a microfluidics device, fluorescence of a recorder (mCherry or mVenus) gene driven by a clock-controlled gene-2 promoter (ccg-2p) was measured simultaneously on over 1000 single cells of Neurospora crassa every half hour for 10 days under each
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ec1312ef3f988963c68750dcb06189
https://doi.org/10.1109/access.2019.2910731
https://doi.org/10.1109/access.2019.2910731
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-24 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-24 (2020)
Stochastic networks for the clock were identified by ensemble methods using genetic algorithms that captured the amplitude and period variation in single cell oscillators of Neurosporacrassa. The genetic algorithms were at least an order of magnitude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7044ec98699895f00ce248c720e85b5e
https://pubmed.ncbi.nlm.nih.gov/32938998
https://pubmed.ncbi.nlm.nih.gov/32938998
Autor:
H.-B. Schüttler, Cristian Caranica, James F. Griffith, Thiab R. Taha, Jonathan Arnold, Ahmad Al-Omari
Publikováno v:
IEEE Access, Vol 6, Pp 54582-54594 (2018)
In the previous paper, we reconstructed the entire transcriptional network for all 2418 clock-associated genes in the model filamentous fungus, Neurospora crassa ( N. crassa ). Several authors have suggested that there is extensive post-transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4294465d50ccca824fb4684d12e04299
https://ieeexplore.ieee.org/document/8471097/
https://ieeexplore.ieee.org/document/8471097/
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Collective cell movement is critical to the emergent properties of many multicellular systems, including microbial self-organization in biofilms, embryogenesis, wound healing, and cancer metastasis. However, even the best-studied systems lack a compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ab14bcd4f8a254aee4e14b234d22bf
https://doi.org/10.1073/pnas.1620981114
https://doi.org/10.1073/pnas.1620981114
Publikováno v:
IEEE Access, Vol 1, Pp 408-417 (2013)
A new numerical technique to solve nonlinear systems of initial value problems for nonlinear first-order differential equations (ODEs) that model genetic networks in systems biology is developed. This technique is based on finding local Galerkin appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee770773a9e0444bebde6485dd802c0
https://doi.org/10.1109/access.2013.2269192
https://doi.org/10.1109/access.2013.2269192
Publikováno v:
IEEE Access, Vol 1, Pp 770-777 (2013)
The adaptive Runge-Kutta (ARK) method on multi-general-purpose graphical processing units (GPUs) is used for solving large nonlinear systems of first-order ordinary differential equations (ODEs) with over ~ 10 000 variables describing a large genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564c34a01f73fe36319e39481cbfe348
https://ieeexplore.ieee.org/document/6662399/
https://ieeexplore.ieee.org/document/6662399/
Autor:
Leidong Mao, Samuel V. Arsenault, Jonathan Arnold, Ahmad Al-Omari, Taotao Zhu, Zhaojie Deng, Cristian Caranica, H.-B. Schüttler, James F. Griffith
Publikováno v:
Scientific Reports
The synchronization of stochastic coupled oscillators is a central problem in physics and an emerging problem in biology, particularly in the context of circadian rhythms. Most measurements on the biological clock are made at the macroscopic level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68a4166e97949ec482875d1c4fdfc37
http://europepmc.org/articles/PMC5082370
http://europepmc.org/articles/PMC5082370
Autor:
James H. Prestegard, Andrew T. Sornborger, John Glushka, H.-B. Schüttler, Yingnan Jiang, Maor Bar-Peled, Janani Varatharajan, Tyler McKinnon
Publikováno v:
Biophysical Journal. 99:2318-2326
The use of nondestructive NMR spectroscopy for enzymatic studies offers unique opportunities to identify nearly all enzymatic byproducts and detect unstable short-lived products or intermediates at the molecular level; however, numerous challenges mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fa190c6dca70f8cf47ffc8ab01fcca
https://doi.org/10.1016/j.bpj.2010.08.014
https://doi.org/10.1016/j.bpj.2010.08.014