Zobrazeno 1 - 10
of 208
pro vyhledávání: '"H. van Es"'
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids
Autor:
Maarten H. Geurts, Shashank Gandhi, Matteo G. Boretto, Ninouk Akkerman, Lucca L. M. Derks, Gijs van Son, Martina Celotti, Sarina Harshuk-Shabso, Flavia Peci, Harry Begthel, Delilah Hendriks, Paul Schürmann, Amanda Andersson-Rolf, Susana M. Chuva de Sousa Lopes, Johan H. van Es, Ruben van Boxtel, Hans Clevers
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Optimization of CRISPR/Cas9-mediated genome engineering has resulted in base editors that hold promise for mutation repair and disease modeling. Here, we demonstrate the application of base editors for the generation of complex tumor models
Externí odkaz:
https://doaj.org/article/118466422c7b4a548268957a251cfb11
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Movie S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0841e5cc268c6b6638bd8b10df5c249
https://doi.org/10.1158/2159-8290.22536523
https://doi.org/10.1158/2159-8290.22536523
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Previous studies have described that tumor organoids can capture the diversity of defined human carcinoma types. Here, we describe conditions for long-term culture of human mucosal organoids. Using this protocol, a panel of 31 head and neck squamous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e4c06e92aae2c945d53df37939ee42
https://doi.org/10.1158/2159-8290.c.6548158.v1
https://doi.org/10.1158/2159-8290.c.6548158.v1
Autor:
Hans Clevers, Alexander van Oudenaarden, Peter J. Peters, David A. Tuveson, Geert J.P.L. Kops, Ruben van Boxtel, Onno Kranenburg, Priya Sridevi, Nino Iakobachvili, Antoni P.A. Hendrickx, Maurice M.J.M. Zandvliet, Judith Vivié, Mauro J. Muraro, Rurika Oka, Richard H. van Jaarsveld, Gui-Wei He, Veerle Geurts, Johan H. van Es, Harry Begthel, Jeroen Korving, Emma J. de Ruiter, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Kadi Lõhmussaar, Sacha Spelier, Sigrid Kolders, Else Driehuis
Supplementary Figures including legends, Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394d1f1adbede503e7e8e1180ac1bfbe
https://doi.org/10.1158/2159-8290.22536505.v1
https://doi.org/10.1158/2159-8290.22536505.v1
Publikováno v:
Yamada's Textbook of Gastroenterology. :31-41
Akademický článek
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Akademický článek
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Autor:
Maarten H. van Es, Mehmet Selman . Tamer, Robbert Bloem, Elfi van Zeijl, Jacques C. J. Verdonck, Adam Chuang, Diederik J. Maas
Publikováno v:
Advances in Patterning Materials and Processes XXXIX.
Autor:
Tineke Veenendaal, Tim Jarvela, Adam G. Grieve, Johan H. van Es, Adam D. Linstedt, Catherine Rabouille
Publikováno v:
Biology Open, Vol 3, Iss 6, Pp 431-443 (2014)
GRASP65 and GRASP55 are peripheral Golgi proteins localized to cis and medial/trans cisternae, respectively. They are implicated in diverse aspects of protein transport and structure related to the Golgi complex, including the stacking of the Golgi s
Externí odkaz:
https://doaj.org/article/b6907d3d39f5408eb68c11a63fe0b61c
Autor:
Benoit Quesson, Paul van Neer, Selman S. Tamer, Kodai Hatakeyama, Maarten H. van Es, Martijn van Riel, Daniele Piras
Publikováno v:
Metrology, Inspection, and Process Control XXXVI.