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Akademický článek

Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer

Autor: H. Y. Chow, B. Dong, C. A. Valencia, C. T. Zeng, J. N. Koch, T. Y. Prudnikova, J. Chernoff

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Group I Paks, like Pak1, are required for the activation of several key oncogenic signaling pathways. Here the authors study an inducible peptide mimicking the auto-inhibitory domain of Pak1 and show promising anti-tumor effects in a mouse model of c

Externí odkaz: https://doaj.org/article/3974d458c1394ee9a963760e6ec8129f

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Evidence of individual differences in the long-term social, psychological, and cognitive consequences of child maltreatment

Autor: Rosa S. Wong, Keith T. S. Tung, Ko Ling Chan, Wilfred H. S. Wong, Hing Wai Tsang, Clare H. Y. Chow, Gilbert T. Chua, Winnie W. Y. Tso, Jason C. Yam, Ian C. K. Wong, Patrick lp

Publikováno v: Child and adolescent psychiatry and mental health. 16(1)

Background The prevalence and consequences of child maltreatment are alarming, but evidence from studies with long follow-up intervals are limited. This study examined the long-term consequences of child maltreatment in relation to age of onset and f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03854f7ae7edebc379583def53884950
https://pubmed.ncbi.nlm.nih.gov/36424655

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Akademický článek

Patient Perception of Physician Attire Before and After Disclosure of the Risks of Microbial Contamination

Autor: Enoch C. T. So, Faraday H. F. Fung, Joshua K. H. Yeung, Lilian H. Y. Chow, Julio S. H. Kwok, Ruby L. Y. Lam, Tommy C. Y. So, Faye S. M. Yu, Dana Vackova, Gilberto K. K. Leung

Publikováno v: International Journal of Medical Students, Vol 1, Iss 3, Pp 109-114 (2013)

Background: The white coat is traditionally considered to be the appropriate attire for physicians but it may also be contaminated with microbes and act as a potential source of infection. We aimed to study patients’ acceptance of physicians’ att

Externí odkaz: https://doaj.org/article/7181ff887a14430783eb46878262adf2

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Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics - Population Specific Model

Autor: Jong Kim, Billy H. Y. Chow, Kingsley H. C. Yim, Moses J.S. Woo, Match W L Ko, Patrick C.K. Ng, Chrissi C. C. Lai

Publikováno v: EMBC

Glaucoma is an eye disorder potentially leading to permanent blindness through the damage of optic nerves at the optic nerve head (ONH). As a critical region of optic nerve damage, the porous Lamina Cribrosa (LC) in the ONH plays a critical role in d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e77f83eda30fb6182c3bcc5e369a23d
https://pubmed.ncbi.nlm.nih.gov/31947070

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PEGylated recombinant human arginase as a drug for breast cancer

Autor: S L, Leung, M K, Ho, Y M, Lam, H Y, Chow, Y H, So, Y C, Leung

Publikováno v: Hong Kong medical journal = Xianggang yi xue za zhi. 25(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::374aef1cc5b18f11a0f5bdccfb8e93db
https://pubmed.ncbi.nlm.nih.gov/31889032

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Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer

Autor: Jonathan Chernoff, Jennifer N. Koch, H. Y. Chow, C. A. Valencia, C. T. Zeng, Biao Dong, Tatiana Y. Prudnikova

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications

p21-activated kinases (Paks) play an important role in oncogenic signaling pathways and have been considered as potential therapeutic targets in various cancers. Most studies of Pak function employ gene knock-out or knock-down methods, but these appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106be836d8449c472b89c3be2ff11b4b
http://link.springer.com/article/10.1038/s41467-018-05935-6

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Arginine deprivation inhibits pancreatic cancer cell migration, invasion and EMT via the down regulation of Snail, Slug, Twist, and MMP1/9

Autor: H Y Chow, Yun Chung Leung, Qing-Fang Li, S C Choi, Huan Wang

Publikováno v: Journal of physiology and biochemistry. 76(1)

Arginine deprivation is currently being evaluated for its efficacy and safety in clinical trials aimed at combating tumors. However, the cellular signaling and molecular changes in response to such deprivation have not been systematically deciphered.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266960f52d5ca9f4c684fe7b6cfc4e14
https://pubmed.ncbi.nlm.nih.gov/31823303

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Evaluation of the Aries

Autor: T, McMillen, H Y, Chow, Shubhagata, Das, Sherry A, Dunbar, N E, Babady

Publikováno v: Journal of clinical microbiology. 57(5)

The Aries Bordetella assay (Aries BA) (Luminex Corporation) recently received FDA clearance for the detection and differentiation of Bordetella pertussis and Bordetella parapertussis nucleic acids in nasopharyngeal swab (NPS) samples. The objective o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dfc10558857f409c7e0219aacc57c9f
https://pubmed.ncbi.nlm.nih.gov/30787143

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Akademický článek

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