Zobrazeno 1 - 10
of 59
pro vyhledávání: '"H. Y. A. Lau"'
Publikováno v:
Allergy. 75(7)
Publikováno v:
Inflammation Research. 66:25-37
The aim of this study was to develop a novel protocol for generating large populations of fully mature and functional human mast cells (HMC) from CD34+ hematopoietic stem cells which require less culturing time than previously reported methods. CD34+
Publikováno v:
International archives of allergy and immunology. 177(3)
Background: Mast cells are key immune effector cells which release chemokines, proteases, and other inflammatory mediators upon activation by immunological stimuli. The aim of this study was to investigate the effects of co-releasing proteases on the
Autor:
Kwok Ho Yip, Clara Bik-San Lau, Chun-Hay Ko, Hoi Ying Lee, Ping-Chung Leung, H. Y. A. Lau, Ben Chung-Lap Chan, Wing-Sum Siu
Publikováno v:
Journal of Pharmacy and Pharmacology. 66:437-444
Objectives Mast cells are believed to contribute to the pathogenesis of osteoporosis as their number is increased in osteoporotic bones. Herba Epimedii, Fructus Ligustri Lucidi and Fructus Psoraleae are three Chinese herbs traditionally for tonifying
Publikováno v:
European Journal of Inflammation, Vol 11 (2013)
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Mast cells play important roles in innate immunity through their activation via toll-like receptors (TLRs) but also contribute to neuroimmunological responses and inflammation through their activation by the neuropeptide substance P (SP) via Gαi/o p
Autor:
Meiling Jin, Bo Yu, Wei Zhang, Wenwen Chen, H. Y. A. Lau, Zhenhe Huang, Zhuo Mao, Yangyang Yu, Weizhen Zhang, Yarui Zhang
Publikováno v:
European journal of pharmacology. 780
Mast cells activated by IgE-dependent and -independent mechanisms play important roles in innate and acquired immune responses. Activation of pertussis toxin (PTX)-sensitive Gi/o proteins is the key step in mast cell degranulation and release of de n
Autor:
D. S. W. Ng, H. Y. A. Lau, Wing Sze Wong, Shou Ping Guan, Wanxing Eugene Ho, J. S. Bian, Chang Cheng, A. H. M. Koh, Tze Khee Chan
Publikováno v:
Allergy. 68:195-203
Background Allergy is an acquired hypersensitivity reaction of the immune system mediated by cross-linking of allergen-specific IgE-bound high-affinity IgE receptors, leading to immediate mast cell degranulation. Artesunate is a semi-synthetic deriva
Publikováno v:
British Journal of Pharmacology. 156:1279-1286
Background and purpose: Although the mast cell is a source of nitric oxide (NO), the effect of NO on human mast cells has not been defined. This study investigated if exogenous NO could affect human mast cell activation. Experimental approach: Effect
Publikováno v:
International Immunopharmacology. 8:764-768
The mast cells have been suggested to be a cellular source of nitric oxide (NO) which level is increased in the pathogenesis of asthma. However, isoforms of the NO generating enzyme, nitric oxide synthase (NOS), in primary human mast cells have not b
Autor:
H. Y. A. Lau, Sven Ingebrandt, Sze-Wing Sam, Mansun Chan, John A. Rudd, Jessica Ka-Yan Law, Chi-Kong Yeung
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 2, Pp 201-212 (2008)
We performed this study to demonstrate the applicability of the microelectrode array (MEA) to study electrophysiological changes of rat peritoneal mast cells in the presence of compound 48/80 under normal, Ca2+-free, Ca2+-free with EDTA, and Cl−-fr