Zobrazeno 1 - 10
of 53
pro vyhledávání: '"H. W. Ziegler-Heitbrock"'
Autor:
Christian Weber, Angelika Pietsch, Wolfgang Erl, M Strobel, H W Ziegler-Heitbrock, Peter C. Weber
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:1665-1673
Cell adhesion to endothelial cells stimulated by tumor necrosis factor-alpha (TNF) is due to induction of surface receptors, such as vascular cell adhesion molecule-1 (VCAM-1). The antioxidant pyrrolidine dithiocarbamate (PDTC) specifically inhibits
Autor:
H W Ziegler-Heitbrock, T Sternsdorf, J Liese, B Belohradsky, C Weber, A Wedel, R Schreck, P Bäuerle, M Ströbel
Publikováno v:
The Journal of Immunology. 151:6986-6993
The human TNF promoter contains four potential nuclear factor-kappa B (NF-kappa B)-binding sites, with the strongest binding seen for the -605 motif. Nuclear extracts from unstimulated cells of the human monocytic cell line, Mono Mac 6, contain one s
Publikováno v:
The Journal of Immunology. 148:2186-2193
When human monocytic Mono Mac 6 cells were treated with bacterial LPS (10 ng/ml, 72 h), they showed an increase in phagocytic activity, superoxide anion production, and expression of monocyte/macrophage-associated cell surface Ag. In these more matur
Autor:
H. W. Ziegler-Heitbrock, Reinhard Andreesen, Peter Fraunberger, M. Blumenstein, P. Boekstegers, G. Fingerle-Rowson
Publikováno v:
Shock. 8:73-75
We describe a patient with self-induced disease who presented with repeated urinary tract infection and sepsis due to intravesical and intravenous injection of feces. Sepsis occurred repeatedly such that the patient exhibited 10 bouts of fever > 40 d
Autor:
E L, Kaijzel, M V, van Krugten, B M, Brinkman, T W, Huizinga, T, van der Straaten, J M, Hazes, H W, Ziegler-Heitbrock, S A, Nedospasov, F C, Breedveld, C L, Verweij
Publikováno v:
Molecular medicine (Cambridge, Mass.). 4(11)
BACKGROUND: Functional heterogeneity in the tumor necrosis factor alpha (TNF-alpha) gene may be responsible for the TNF-alpha response in infectious and autoimmune diseases. Recently, the TNF-238 promoter polymorphism was observed as being associated
Autor:
M, Haas, S, Page, M, Page, F J, Neumann, N, Marx, M, Adam, H W, Ziegler-Heitbrock, D, Neumeier, K, Brand
Publikováno v:
Journal of leukocyte biology. 63(3)
We investigated the effect of proteasome inhibitors on the lipopolysaccharide (LPS)-induced expression of several monocytic cytokines, which may be dependent on the transcription factor, nuclear factor-kappaB (NF-kappaB). Exposure of human monocytic
Publikováno v:
Blood. 87(1)
The subpopulation of strongly CD14-positive (CD14++) monocytes and monocytes coexpressing the CD16 antigen and low levels of CD14 (CD14+/CD16+ cells) were isolated by fluorescence-activated cell sorting (FACS) followed by stimulation with lipopolysac
Publikováno v:
Journal of inflammation. 46(2)
Cells of the monocyte/macrophage lineage are heterogenous in that some types express the CD16 molecule (Fc receptor for IgG, type III), while others are negative. We now show that culture of human blood monocytes with interleukin-10 (IL-10) will indu
Autor:
C, Weber, E, Negrescu, W, Erl, A, Pietsch, M, Frankenberger, H W, Ziegler-Heitbrock, W, Siess, P C, Weber
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(1)
We studied the role of tyrosine phosphorylation in the induction of vascular cell adhesion molecule 1 (VCAM-1), endothelial leukocyte adhesion molecule 1 (ELAM-1), and intercellular adhesion molecule 1 (ICAM-1) in HUVEC. Induction of VCAM-1 and ELAM-
Autor:
A, Pforte, A, Schiessler, S, Kressenstein, P, Gais, B, Beer, K, Hüssinger, G, Riethmüller, H W, Ziegler-Heitbrock
Publikováno v:
Journal of clinicallaboratory immunology. 46(3)
The intercellular adhesion molecule-1 (ICAM-1) is important in mediating intercellular contact in inflammation. Therefore, we have analyzed the expression of this molecule on alveolar macrophages (AM) and in serum of patients with sarcoidosis. Bronch