Zobrazeno 1 - 6
of 6
pro vyhledávání: '"H. W. T. van Vlijmen"'
Autor:
B. J. Bongers, M. Gorostiola González, X. Wang, H. W. T. van Vlijmen, W. Jespers, H. Gutiérrez-de-Terán, K. Ye, A. P. IJzerman, L. H. Heitman, G. J. P. van Westen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract G Protein-coupled receptors (GPCRs) are the most frequently exploited drug target family, moreover they are often found mutated in cancer. Here we used a dataset of mutations found in patient samples derived from the Genomic Data Commons and
Externí odkaz:
https://doaj.org/article/398bb36bd7d64e68b95c7d13e8e7de3f
Publikováno v:
Journal of Molecular Biology. 275:295-308
Foot-and-mouth disease virus (FMDV), a non-enveloped picornavirus, is sensitive to acidic conditions. At pH values below 7 the icosahedral virus capsid, formed from 60 copies of a protomer containing four polypeptides (VP1 to 4), dissociates into 12
Publikováno v:
Proteins: Structure, Function, and Genetics. 23:318-326
We evaluate 3D models of human nucleoside diphosphate kinase, mouse cellular retinoic acid binding protein I, and human eosinophil neurotoxin that were calculated by MODELLER, a program for comparative protein modeling by satisfaction of spatial rest
Publikováno v:
Biopolymers. 30:517-532
The formation of triple-stranded nucleic acid helices is studied by molecular mechanics and molecular dynamics calculations. Using standard TAT and CGG homopolymers, single, triple, and quintuple molecular replacements are made. Some of these replace
Autor:
Martin Karplus, H. W. T. Van Vlijmen
Publikováno v:
Journal of molecular biology. 267(4)
An approach to loop prediction that starts with a database search is presented and analyzed. To obtain meaningful statistics, 130 loops from 21 proteins were studied. The correlation between the internal conformation of the loop and the conformation