Zobrazeno 1 - 10
of 14
pro vyhledávání: '"H. W. Löms Ziegler-Heitbrock"'
Autor:
Dieter Neumeier, Andreas Zwergal, Susanne A. Bell, Peter Heiss, Martina Quirling, Marion Weber, Carmen Sydlik, Caroline Nothdurfter, Korbinian Brand, H. W. Löms Ziegler-Heitbrock
Publikováno v:
J. Biol. Chem. 278, 23586-23593 (2003)
There is some evidence that the potent cytokine tumor necrosis factor (TNF) is able to induce tolerance after repeated stimulation of cells. To investigate the molecular mechanisms mediating this phenomenon, the expression of interleukin-8 (IL-8), wh
Autor:
Ursula Kreusel, Claudia Fischer, B. Baumgartner, Marianne Hayn, Sharon Page, Monika Haas, Günther Loidl, H. W. Löms Ziegler-Heitbrock, Korbinian Brand, Dieter Neumeier
Publikováno v:
Journal of Biological Chemistry. 274:11611-11618
Extensively oxidized low density lipoprotein (ox-LDL), a modulator of atherogenesis, down-regulates the lipopolysaccharide (LPS)-induced activation of transcription factor NF-kappaB. We investigated whether 4-hydroxynonenal (HNE), a prominent aldehyd
Publikováno v:
Infection and Immunity. 67:1553-1559
Monocytes respond to lipopolysaccharide (LPS) stimulation with a rapid expression of the tumor necrosis factor (TNF) gene. Upon repeated LPS stimulation there is, however, little production of TNF mRNA and protein; i.e., the cells are tolerant to LPS
Publikováno v:
Immunobiology. 198:81-90
When monocytes are stimulated with LPS (lipopolysaccharide) repeatedly then the initially high expression of the TNF (tumor necrosis factor) gene is only very low, i.e. the cells are tolerant to LPS. Tolerant cells still express the CD14 receptor and
Autor:
Johannes Möst, Christine Claus, H. W. Löms Ziegler-Heitbrock, Manfred P. Dierich, Hartwig P. Huemer, M Strobel, Wilhelm J. Schwaeble, K. B. M. Reid
Publikováno v:
European Journal of Biochemistry. 219:759-764
Properdin is the only known positive regulator of the alternative pathway of complement activation. Northern blot analysis of cell lines derived from fibroblasts, B-cells, hepatoma cells, and cells of the monocyte-macrophage lineage revealed properdi
Autor:
Matthias Mack, H. W. Löms Ziegler-Heitbrock, Farshid Dayyani, Birgit Steppich, Reinhard Lorenz, Rudolf Gruber
Publikováno v:
American journal of physiology. Cell physiology. 279(3)
Strenuous, anaerobic exercise leads to an increase of leukocytes that are mobilized from the marginal pool. We have analyzed in human peripheral blood the effect of exercise on the number of CD14+CD16+monocytes as determined by two-color immunofluore
Autor:
Christian Weber, Philipp von Hundelshausen, H. W. Löms Ziegler-Heitbrock, Marion Frankenberger, Georg Draude
Publikováno v:
The American journal of physiology. 276(4)
The CD14+/CD16+subset of human blood monocytes, which expresses low levels of the lipopolysaccharide receptor CD14 and high levels of the Fc receptor CD16 and exhibits features of mature tissue macrophages, is expanded in certain inflammatory conditi
Publikováno v:
Journal of Investigative Dermatology. 95(6):S213-S215
The effectiveness of interferon (IFN) therapy in malignant lymphoma is analyzed in this review. Although various treatment regimens including IFN at various dose levels have so far not proved to have curative potential, a substantial palliative effec
Publikováno v:
Immunobiology. 198(1-3)
Cells of the murine macrophage cell line P388D1 express cell surface CD14 and respond to LPS(lipopolysaccharide) stimulation with the production of TNF (tumor necrosis factor). When the cells are stimulated with LPS a second time then little TNF is p
Publikováno v:
Immunobiology. 193(2-4)
When monocytes are stimulated with Lipopolysaccharide (LPS), they efficiently produce cytokines like tumor necrosis factor (TNF). Upon secondary stimulation, this response is only minimal, and there is little TNF mRNA transcription, mRNA accumulation