Zobrazeno 1 - 8
of 8
pro vyhledávání: '"H. W. F. M. De Gouw"'
Publikováno v:
Journal of Applied Physiology. 81:673-678
The membrane-bound metalloproteinase, neutral endopeptidase (NEP), is a degrading enzyme of both bronchoconstrictor and bronchodilator peptides within the airways. To examine the role of NEP in exercise-induced bronchoconstriction (EIB) in asthmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07799fa79cb893600e7b709a145647dc
https://doi.org/10.1152/jappl.1996.81.2.673
https://doi.org/10.1152/jappl.1996.81.2.673
Publikováno v:
Thorax, 54(7), 565-567. BMJ Publishing Group
Scopus-Elsevier
Scopus-Elsevier
There is worldwide increasing awareness of the human and socioeconomic impact of chronic obstructive pulmonary disease (COPD) which is a major cause of morbidity and mortality.1 Even though its pathogenesis in industrialised countries is linked to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a5caa055ad8c4a1352e1254f2bbb34
https://doi.org/10.1136/thx.54.7.565
https://doi.org/10.1136/thx.54.7.565
Publikováno v:
Thorax, 54(11), 1033-1035. BMJ Publishing Group
BACKGROUND—Nitric oxide (NO) may exert protective properties within the airways of asthmatic patients. It was postulated that airways obstruction in asthma may be associated with endogenous NO deficiency caused by limited availability of NO synthas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4681eb1f0686cf83065b6fc8847ea858
https://doi.org/10.1136/thx.54.11.1033
https://doi.org/10.1136/thx.54.11.1033
Autor:
J. G. van den Aardweg, H. van der Veen, S. J. Marshall-Partridge, Pieter S. Hiemstra, H. W. F. M. De Gouw, P. J. Sterk
Publikováno v:
Journal of applied physiology (Bethesda, Md., 90(2), 586-592. American Physiological Society
A role of nitric oxide (NO) has been suggested in the airway response to exercise. However, it is unclear whether NO may act as a protective or a stimulatory factor. Therefore, we examined the role of NO in the airway response to exercise by using N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff1ef71070d07fc6ea4702b653adeb6
https://pure.amc.nl/en/publications/role-of-nitric-oxide-in-the-airway-response-to-exercise-in-healthy-and-asthmatic-subjects(2ec267e6-5146-457a-8529-b85e0db7551b).html
https://pure.amc.nl/en/publications/role-of-nitric-oxide-in-the-airway-response-to-exercise-in-healthy-and-asthmatic-subjects(2ec267e6-5146-457a-8529-b85e0db7551b).html
Publikováno v:
European respiratory journal, 11(1), 126-132. European Respiratory Society
Exhaled nitric oxide (NO) is elevated in asthmatics, and varies with disease severity. We postulated that a respiratory virus infection increases exhaled NO levels in asthma, and examined the relationship between the virus-induced changes in exhaled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f9d391bfe032205b4c57b5e6d03b78
https://pure.amc.nl/en/publications/relationship-between-exhaled-nitric-oxide-and-airway-hyperresponsiveness-following-experimental-rhinovirus-infection-in-asthmatic-subjects(a281efd7-4dfa-42fc-bcbc-66500fd9b68c).html
https://pure.amc.nl/en/publications/relationship-between-exhaled-nitric-oxide-and-airway-hyperresponsiveness-following-experimental-rhinovirus-infection-in-asthmatic-subjects(a281efd7-4dfa-42fc-bcbc-66500fd9b68c).html
Publikováno v:
American journal of respiratory and critical care medicine, 158(1), 315-319. American Thoracic Society
Exhaled NO is increased in patients with asthma and may reflect disease severity. We examined whether the level of exhaled NO is related to the degree of airway obstruction induced by direct and indirect stimuli in asthma. Therefore, we measured exha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853a78e95357b2232e64d77f1abb8350
https://pure.amc.nl/en/publications/exhaled-nitric-oxide-no-is-reduced-shortly-after-bronchoconstriction-to-direct-and-indirect-stimuli-in-asthma(88b74af1-0aee-44a7-8be7-36b39b3a289e).html
https://pure.amc.nl/en/publications/exhaled-nitric-oxide-no-is-reduced-shortly-after-bronchoconstriction-to-direct-and-indirect-stimuli-in-asthma(88b74af1-0aee-44a7-8be7-36b39b3a289e).html
Autor:
Aloys C.M. Kroes, P. J. Sterk, E. C. Dick, H. W. F. M. De Gouw, E. A. P. Kuijpers, Katrien Grünberg, E. P. A. De Klerk
Publikováno v:
American journal of respiratory and critical care medicine, 155(3), 833-838. American Thoracic Society
Disturbance of the balance between excitatory and inhibitory activity of the airway sensory nerves has been implicated in asthma pathogenesis, particularly during exacerbations of the disease. The objective of this study was to examine the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92eac62343923c68d1ff9926aacaec7f
https://pubmed.ncbi.nlm.nih.gov/9117013
https://pubmed.ncbi.nlm.nih.gov/9117013
Autor:
E.H.D. Bel, J C C M In 't Veen, H. W. F. M. De Gouw, Jacob K. Sont, P. J. Sterk, Pieter S. Hiemstra, Hermelijn H. Smits
Publikováno v:
The European respiratory journal. 9(12)
Sputum induced by inhalation of nebulized hypertonic saline is increasingly used to monitor airways inflammation in asthma. The aim of this study was to assess the repeatability of measuring cellular and soluble markers of inflammation in whole sputu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab537093d0aca5528aaeab29bfd5d6a
https://pubmed.ncbi.nlm.nih.gov/8980948
https://pubmed.ncbi.nlm.nih.gov/8980948