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Autor:
H. Vidrio
Publikováno v:
Autonomic and Autacoid Pharmacology. 23:275-283
1. The characteristics of semicarbazide-sensitive amine oxidase (SSAO) are reviewed and the unknown physiological or pathological role of this enzyme emphasized. 2. The various mechanisms of action proposed for the vasodilator drug hydralazine are co
Publikováno v:
Journal of Neural Transmission. 114:863-865
The endogenous compound hydroxylamine relaxes vascular smooth muscle in vitro, apparently through conversion to the vasodilator factor nitric oxide, but its effect on blood pressure has not been characterized. We found that in the anesthetized rat th
Autor:
G Fernández, H Vidrio
Publikováno v:
Journal of Cardiovascular Pharmacology. 32:378-381
The influence of isoniazid (ISO) preincubation on the relaxant effects of a group of nitrovasodilators was examined in norepinephrine-contracted rat aortic rings with and without endothelium. ISO displaced to the left the dose-response curves to all
Autor:
H. Vidrio, M A Sánchez-Salvatori
Publikováno v:
Autonomicautacoid pharmacology. 23(1)
1. It is generally recognized that the vasodilator hydralazine produces hypotension accompanied by baroreflex-mediated tachycardia. In some experimental conditions, however, the accompanying heart rate change is bradycardia, a paradoxical response wh
Publikováno v:
General pharmacology. 35(4)
The influence of pretreatment with 1 through 300 mg/kg ip of isoniazid (ISO) on blood pressure and heart rate responses to 0.1 mg/kg iv of hydralazine (HYD) was assessed in rats anesthetized with chloralose--urethane. HYD hypotension was significantl
Publikováno v:
Gaceta medica de Mexico. 136(4)
Publikováno v:
Archives of medical research. 28(2)
This work examined the effects of nicotine on mean arterial pressure and heart rate in non-anesthetized spinal rats. Nicotine (200 mg/kg) was administered as a single bolus, as infusions lasting 7.5, 15 or 30 min, and as a post-infusion bolus. A nico
Publikováno v:
Archivos del Instituto de Cardiologia de Mexico. 67(3)
Among its different activities the Mexican Health Ministry (SSA) promotes: 1) the specification of biological standards for the Mexican population; 2) mechanisms for early detection of physiopathological changes and 3) development of the appropriate
Autor:
H, Vidrio
Publikováno v:
Archives of medical research. 27(3)
Hydralazine (H) induces hypotension accompanied by cardiac stimulation due to activation of the arterial baroreflex. Both clinical and experimental observations suggest, however, that in certain conditions H hypotension can be accompanied by unchange