Zobrazeno 1 - 10
of 109
pro vyhledávání: '"H. Vasken Aposhian"'
Autor:
H. Vasken Aposhian, Marisa F. Naujokas, Habibul Ahsan, William A. Suk, Joseph H. Graziano, Beth Anderson, Claudia Thompson
Publikováno v:
Environmental Health Perspectives
Background: Concerns for arsenic exposure are not limited to toxic waste sites and massive poisoning events. Chronic exposure continues to be a major public health problem worldwide, affecting hundreds of millions of persons. Objectives: We reviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289d7418f8730223870ce78bd6d25841
http://europepmc.org/articles/PMC3621177
http://europepmc.org/articles/PMC3621177
Autor:
Uttam K. Chowdhury, H. Vasken Aposhian
Publikováno v:
Annals of the New York Academy of Sciences. 1140:325-334
Hamsters were exposed to sodium arsenite (173 mg As/L) in drinking water for 6 days and control hamsters were given tap water. Equal amounts of protein from the urinary bladder or liver extracts of control and arsenic-treated hamsters were labeled wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784f4a4f6207334ae560e23da960de11
https://doi.org/10.1196/annals.1454.019
https://doi.org/10.1196/annals.1454.019
Autor:
H. Vasken Aposhian, Michael J. Kopplin, Mihaela D. Avram, Robert A. Zakharyan, Uttam K. Chowdhury, Alba Hernández
Publikováno v:
Toxicology and Applied Pharmacology. 216:446-457
Inorganic arsenic is a human carcinogen to which millions of people are exposed via their naturally contaminated drinking water. Its molecular mechanisms of carcinogenicity have remained an enigma, perhaps because arsenate is biochemically transforme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e4de4853b8b40ffd7e7e4e78b57b9a
https://doi.org/10.1016/j.taap.2006.06.014
https://doi.org/10.1016/j.taap.2006.06.014
Autor:
Robert A. Zakharyan, Michael L. Wollenberg, Mihaela D. Avram, H. Vasken Aposhian, Adriana Sampayo-Reyes
Publikováno v:
Toxicology and Applied Pharmacology. 198:327-335
This laboratory has studied the enzymology involved in the biotransformation of inorganic arsenic to dimethylarsinous acid (DMA(III)) and in human studies established that monomethylarsonous acid (MMA(III)) and DMA(III) appear in urine of people chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758ab6d818c96ec4a28438e2ddb0fd16
https://doi.org/10.1016/j.taap.2003.10.027
https://doi.org/10.1016/j.taap.2003.10.027
Publikováno v:
Toxicology and Applied Pharmacology. 193:309-334
The aim of this review is to compare the metabolism, chemistry, and biological effects to determine if either of the industrial arsenicals (arsine and gallium arsenide) act like the environmental arsenic oxides (arsenite and arsenate). The metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7b81f543d20ee692e9fec23cfa260e
https://doi.org/10.1016/j.taap.2003.07.009
https://doi.org/10.1016/j.taap.2003.07.009
Autor:
Robert A. Zakharyan, Mihaela D. Avram, Michael L. Wollenberg, H. Vasken Aposhian, Michael J. Kopplin
Publikováno v:
Toxicology and Applied Pharmacology. 193:1-8
Arsenic compounds with a +3 oxidation state are more toxic than analogous compounds with a +5 oxidation state, for example, arsenite versus arsenate, monomethylarsonous acid (MMA(III)) versus monomethylarsonic acid (MMA(V)), and dimethylarsinous acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01808e88a22be72e5e68a863fe773c1
https://doi.org/10.1016/s0041-008x(03)00324-7
https://doi.org/10.1016/s0041-008x(03)00324-7
Autor:
Hiroshi Yamauchi, H. Vasken Aposhian, Mariano E. Cebrián, Ellen K. Silbergeld, Christopher A. Loffredo
Publikováno v:
Environmental Research. 92:85-91
Estimating the nature and extent of human cancer risks due to arsenic (As) in drinking water is currently of great concern, since millions of persons worldwide are exposed to arsenic, primarily through natural enrichment of drinking water drawn from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f4c3e90a262643bc014393a35722ed
https://doi.org/10.1016/s0013-9351(02)00081-6
https://doi.org/10.1016/s0013-9351(02)00081-6
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 46:373-377
Summary A short and efficient synthesis of sodium dimethylarsinate- 14 C is described. Incorporation of the label has been achieved by methylation of methyldiiodoarsine with iodomethane- 14 C. Product was precipitated and separated from sodium iodide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0240165ee74df4a261787bcfaebb7981
https://doi.org/10.1002/jlcr.667
https://doi.org/10.1002/jlcr.667
Publikováno v:
Chemical Research in Toxicology. 15:1318-1323
Sodium 2,3-dimercapto-1-propane sulfonate (DMPS) has been used to treat acute arsenic poisoning. Presumably DMPS functions by chelating some arsenic species to increase the excretion of arsenic from the body. However, the excreted complex of DMPS wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c9e804b65846ef11141ed1f5973069
https://doi.org/10.1021/tx020058m
https://doi.org/10.1021/tx020058m