Zobrazeno 1 - 10
of 614
pro vyhledávání: '"H. Thorpe"'
ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background Colony growth on solid media is a simple and effective measure for high-throughput genomic experiments such as yeast two-hybrid, synthetic dosage lethality and Synthetic Physical Interaction screens. The development of robotic pin
Externí odkaz:
https://doaj.org/article/df32d7f65ac64d1384c8e3be87bef450
Autor:
Cinzia Klemm, Henry Wood, Grace Heredge Thomas, Guðjón Ólafsson, Mara Teixeira Torres, Peter H. Thorpe
Publikováno v:
Microbial Cell, Vol 8, Iss 12, Pp 280-296 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the highly infectious coronavirus disease COVID-19. Extensive research has been performed in recent months to better understand how SARS-CoV-2 infects and ma-nipul
Externí odkaz:
https://doaj.org/article/83532c3e718c44c5865eb0d261090653
Autor:
Nitika, Bo Zheng, Linhao Ruan, Jake T Kline, Siddhi Omkar, Jacek Sikora, Mara Texeira Torres, Yuhao Wang, Jade E Takakuwa, Romain Huguet, Cinzia Klemm, Verónica A Segarra, Matthew J Winters, Peter M Pryciak, Peter H Thorpe, Kazuo Tatebayashi, Rong Li, Luca Fornelli, Andrew W Truman
Publikováno v:
PLoS Biology, Vol 20, Iss 10, p e3001839 (2022)
Hsp70 interactions are critical for cellular viability and the response to stress. Previous attempts to characterize Hsp70 interactions have been limited by their transient nature and the inability of current technologies to distinguish direct versus
Externí odkaz:
https://doaj.org/article/59fc76cc577d413db19b096830ece4f5
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
The emergence of COVID-19 immediately affected higher education, and the closure of campuses at the start of the pandemic in March of 2020 forced educational institutions to quickly adapt to changing circumstances. Schools of public health faced chal
Externí odkaz:
https://doaj.org/article/de749e6ade224529b955a4840b69e2f2
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-21 (2020)
Abstract Background The creation of arrays of yeast strains each encoding a different protein with constant tags is a powerful method for understanding how genes and their proteins control cell function. As genetic tools become more sophisticated the
Externí odkaz:
https://doaj.org/article/79cb272c3491436ca09cc6c46aa64e58
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2183-2194 (2019)
The yeast centrosome or Spindle Pole Body (SPB) is an organelle situated in the nuclear membrane, where it nucleates spindle microtubules and acts as a signaling hub. Various studies have explored the effects of forcing individual proteins to interac
Externí odkaz:
https://doaj.org/article/bfc9c42955fa47d9bacf5594b0afa342
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000917 (2020)
The transition from mitosis into the first gap phase of the cell cycle in budding yeast is controlled by the Mitotic Exit Network (MEN). The network interprets spatiotemporal cues about the progression of mitosis and ensures that release of Cdc14 pho
Externí odkaz:
https://doaj.org/article/124663b682b34556b1d447529054a335
Autor:
Guðjón Ólafsson, Peter H Thorpe
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008990 (2020)
The kinetochore, a multi-protein complex assembled on centromeres, is essential to segregate chromosomes during cell division. Deficiencies in kinetochore function can lead to chromosomal instability and aneuploidy-a hallmark of cancer cells. Kinetoc
Externí odkaz:
https://doaj.org/article/5226d4efd5b0464898b370deb0e9d3d8
Publikováno v:
Environmental Management. 70:448-463
ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-15 (2022)
BMC Bioinformatics
BMC Bioinformatics
Background Colony growth on solid media is a simple and effective measure for high-throughput genomic experiments such as yeast two-hybrid, synthetic dosage lethality and Synthetic Physical Interaction screens. The development of robotic pinning tool