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Angiographic dose-finding study with r-hirudin (HBW 023) for the improvement of thrombolytic therapy with streptokinase (HIT-SK). Interim results

Autor: GertJan Laarman, P. Zijnen, Dirk J. Lok, L. H. Takens, C. M. Luz, D. P. Hertzberger, J. H. Kingma, A. H. Bosma, A. A. van den Bos, G. P. Molhoek

Publikováno v: European heart journal. 16

To evaluate the efficacy and safety of hirudin, a direct thrombin inhibitor, in patients with acute myocardial infarction, a dose-finding, angiography study rvas carried out. After a pilot phase in 10 patients treated with a bolus of 0·1 mg . kg−1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e748dfee9180c308d023d73f69d24bc3
https://pubmed.ncbi.nlm.nih.gov/8542870

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The course of alcohol amnestic disorder: a three-year follow-up study of clinical signs and social disabilities

Autor: B. A. Blansjaar, H. Takens, A. H. Zwinderman

Publikováno v: Acta psychiatrica Scandinavica. 86(3)

Forty-four patients with alcohol amnestic disorder were prospectively studied from 1987 to 1990. The cognitive impairment, social disability and mental symptoms of patients under different conditions were compared. Thirty-three patients (75%) had no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe78c97cb37575fb7d46fb6631b8013
https://pubmed.ncbi.nlm.nih.gov/1414421

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A systemic non-lytic state and local thrombolytic failure of anistreplase (anisoylated plasminogen streptokinase activator complex, APSAC) in acute myocardial infarction

Autor: J van der Meer, Hans L. Hillege, Kong I. Lie, Johan Brügemann, B. H. Takens

Publikováno v: British heart journal. 64(6)

The relation between coronary thrombolysis and coagulation variables after administration of anistreplase (anisoylated plasminogen streptokinase activator complex, APSAC) was studied in patients with an acute myocardial infarction. Fifty eight consec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a6847114a8ae5be2ac400a4b2b461d
https://pubmed.ncbi.nlm.nih.gov/2271340

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Logistical problems in prehospital thrombolysis

Autor: J. Der Van Meer, Johan Brügemann, Kong I. Lie, P. A. De Graef, L. H. Takens

Publikováno v: European Heart Journal, 13(6), 787-788. Oxford University Press

In this study we compared efficacy and safety of prehospital with in-hospital thrombolytic treatment with anistreplase in patients with acute myocardial infarction (AMI). Three-hundred and fifty patients with chest pain were screened for eligibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5935049b226a848cfa9ee2bf1a6d352e
https://doi.org/10.1093/oxfordjournals.eurheartj.a060257

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