Zobrazeno 1 - 10
of 320
pro vyhledávání: '"H. T. Karnes"'
Publikováno v:
Biomarkers. 11:449-459
Each year in the USA approximately 7-8 million patients with non-traumatic chest pain come to hospital emergency rooms. It is estimated that approximately 2-5% of these patients are experiencing cardiac ischaemia, but due to the shortcomings of the a
Publikováno v:
Journal of Chromatography B. 825:98-110
High performance liquid chromatography with atmospheric pressure ionization (API) mass spectrometry has been essential to a large number of quantitative analytical applications for a variety of compounds. Poor detection sensitivity however is a probl
Autor:
S. Bhoopathy, H. T. Karnes
Publikováno v:
Biomedical Chromatography. 16:1-6
Capillary electrophoresis (CE) has been used with collinear laser-induced fluorescence detection (LIF) to determine the amount of (3S)-3-hydroxy quinidine (3OHQ) formed on direct injection of microsomal incubation mixtures. 3OHQ is the CYP 3A4 metabo
Publikováno v:
Biomedical Chromatography. 15:100-107
This paper describes the validation of an analytical method for the determination of amphetamine in beagle dog plasma by gas chromatography coupled to mass spectrometry (GC-MS). d-Amphetamine-d6 was used as the internal standard. The method consisted
Autor:
Gérard Hopfgartner, D Tsikas, T. M. Phillips, G Xu, David K. Lloyd, Rainer Bischoff, H. T. Karnes
Publikováno v:
Journal of Chromatography B. 860:1-3
Autor:
H. T. Karnes, A Ellingson
Publikováno v:
Biomedical Chromatography. 12:8-12
Peroxyloxalate chemiluminescence is well established as a tool for improvement of selectivity and sensitivity for chemiluminophores and their derivations in HPLC eluates. Chemiluminescence in the far-red spectral region was investigated in this work
Autor:
H T Karnes, S V Rahavendran
Publikováno v:
Analytical Chemistry. 69:3022-3027
This study reports the application of Nile blue (NB), a farred oxazine label, as a precolumn derivatization reagent for the measurement of free levels of phenylacetic acid (PAA) in plasma. The measurement of PAA in psychiatric populations is importan
Publikováno v:
Biomedical Chromatography. 10:318-324
A highly sensitive HPLC method with conventional and laser-induced fluorescence detection for the analyses of oestrogens is described. beta-oestradiol (beta-ES) was chosen as a model and derivatized with pyrenesulphonyl chloride (PSCL), a novel deriv
Publikováno v:
Critical Care Medicine. 23:1061-1066
To determine the chemical compatibility of three different triple drug admixtures diluted with either 5% dextrose in water or 0.9% NaCl solution when administered via a multiple line infusion system (Omni-Flow 4000, Abbott Laboratories, Abbott Park,
Autor:
C March, H T Karnes
Publikováno v:
Pharmaceutical Research. 10:1420-1426
Accuracy and precision are the most important criteria in the assessment of an analytical method, and monitoring quality control during sample analysis is essential to ensure the validity of reported results. Various approaches to testing accuracy, p