Zobrazeno 1 - 10
of 33
pro vyhledávání: '"H. T. Heidemann"'
Publikováno v:
Mycoses. 32:638-643
Hepatotoxicity is a well-known side effect of the antifungal drug 5-fluorocytosine. The underlying mechanisms of this toxicity are unknown. The present in vitro study was, therefore, designed to assess the influence of 5-fluorocytosine and 5-fluorour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38879f880231267eb312d982973f47dc
https://doi.org/10.1111/j.1439-0507.1989.tb02196.x
https://doi.org/10.1111/j.1439-0507.1989.tb02196.x
Autor:
H. T. Heidemann, K. H. Brune
Publikováno v:
Mycoses. 34:401-404
Summary. Fluey tosine (5-fluorocytosine), a potent antimycotic drug against various systemic infections such as candidosis, aspergillosis and cryptococcosis, is extensively excreted by the kidneys, yet its possible role in renal function is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be9e11cb03b48a86ed195a81cd15c034
https://doi.org/10.1111/j.1439-0507.1991.tb00802.x
https://doi.org/10.1111/j.1439-0507.1991.tb00802.x
Publikováno v:
Mycoses. 46:169-173
The effect of amphotericin B application on urinary renal tubule enzyme excretion was investigated in rats treated with amphotericin B (1.5 mg kg-1 b.i.d., i.v.) for 4 days. Application of amphotericin B induced a significant higher daily urinary enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe67e85f59e563a5d45fcb08a5b60e02
https://doi.org/10.1046/j.1439-0507.2003.00856.x
https://doi.org/10.1046/j.1439-0507.2003.00856.x
Publikováno v:
Pharmacology. 55:87-94
The influence of amphotericin B on various cytochrome P450-dependent mixed-function oxidases, antipyrine clearance and glucose-6-phosphatase was investigated in rats treated daily with deoxycholate amphotericin B (3 mg/kg body weight, intravenously)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e6b8e46a7afa6457fece43f943b803
https://doi.org/10.1159/000139516
https://doi.org/10.1159/000139516
Publikováno v:
Nephron. 70:425-429
To determine whether inhibition of lipid peroxidation modifies cisplatin-induced changes of renal p-aminohippurate (PAH) uptake, we examined the effects of various radical scavengers and torbafylline on cisplatin-induced lipid peroxidation and PAH ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f07d66188814c0563b087d76ae6acff6
https://doi.org/10.1159/000188640
https://doi.org/10.1159/000188640
Publikováno v:
Journal of Hepatology. 14:300-304
The effect of amphotericin B on hepatic microsomal cytochrome P-450 (P-450) concentration was measured in vitro, in vivo and ex vivo in the rat. In vitro, both amphotericin B (0-500 micrograms/ml) and its vehicle, sodium deoxycholate (0-410 microgram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6edbe90da8c8c57d5048d63fa20941
https://doi.org/10.1016/0168-8278(92)90174-n
https://doi.org/10.1016/0168-8278(92)90174-n
Publikováno v:
Renal Failure. 14:17-21
The influence of amphotericin B on PAH transport as well as on lipid peroxidation in rat renal cortical slices was studied in vitro and ex vivo. In vitro, renal cortical slices were incubated with different amphotericin B (AmB) concentrations (2-60 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33732e1a56a3c1f5b1cd3803bd133aa
https://doi.org/10.3109/08860229209039112
https://doi.org/10.3109/08860229209039112
Publikováno v:
Antimicrobial Agents and Chemotherapy. 44:131-133
The effects of conventional amphotericin B (AmB) dissolved in sodium deoxycholate on microsomal cytochrome P-450 concentrations and propafenone metabolism to 5-hydroxy-propafenone and N -desalkyl-propafenone were compared with those of liposomal AMB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d4b80fb96858c14035133df7b91b03
https://doi.org/10.1128/aac.44.1.131-133.2000
https://doi.org/10.1128/aac.44.1.131-133.2000
Publikováno v:
Clinical Pharmacology and Therapeutics. 48:575-581
Serum γ-glutamyltransferase is used as a marker of hepatic enzyme induction. The kidney contains high activities of γ-glutamyltransferase in the brush border membrane of the proximal tubule, from which it is released into urine. This study investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ec5aefa93db539880c039d332ead02
https://doi.org/10.1038/clpt.1990.194
https://doi.org/10.1038/clpt.1990.194
Publikováno v:
Mycoses. 42(7-8)
In the present study we investigated the influence of AmBisome®, a lyophilized liposomal amphotericin B formulation on various hepatic cytochrome P450-dependent mixed function oxidases, antipyrine clearance and hepatic glucose-6-phosphatase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356d22e152d7d251f45d4d846cebb641
https://pubmed.ncbi.nlm.nih.gov/10546487
https://pubmed.ncbi.nlm.nih.gov/10546487