Zobrazeno 1 - 10
of 141
pro vyhledávání: '"H. Streiff"'
Publikováno v:
Journal of the Serbian Chemical Society, Vol 78, Iss 11, Pp 1655-1670 (2013)
The mechanism(s) of volatile anesthetics (VAs) are poorly under- stood. High-resolution NMR spectroscopy was used to determine the structure of the halothane-(Ca 2+ )4-calmodulin ((Ca 2+ )4- CaM) complex, and it was found that halothane molecules bin
Autor:
Keith A. Jones, Slobodan Macura, Elena Atanasova, John H. Streiff, Thomas Wesley Allen, Nenad Juranić, Alan R. Penheiter
Publikováno v:
Biophysical Journal. 91:3405-3414
Computational methods designed to predict and visualize ligand protein binding interactions were used to characterize volatile anesthetic (VA) binding sites and unoccupied pockets within the known structures of VAs bound to serum albumin, luciferase,
Autor:
David O. Warner, Nenad Juranić, Keith A. Jones, William J. Perkins, Slobodan Macura, John H. Streiff
Publikováno v:
Molecular Pharmacology. 66:929-935
The effects of anesthetics on cellular function may result from direct interactions between anesthetic molecules and proteins. These interactions have a low affinity and are difficult to characterize. To identify proteins that bind anesthetics, we us
Autor:
Jeanne L. McHale, J. H. Streiff
Publikováno v:
The Journal of Chemical Physics. 112:841-850
The electronic transitions of [Ru(NH3)4bipyridine]2+(R4AB) in the visible region are solvatochromic due to hydrogen bonding interactions with the solvent. In this work, we employ resonance Raman and absorption spectroscopy to separate the static and
Publikováno v:
Chemical Physics Letters. 312:369-375
The electronic transitions of [Ru(NH 3 ) 4 bipyridine] 2+ were examined. The two longest wavelength absorption bands red-shift with increasing Gutmann donor number of the solvent, and the lowest energy band is split by about 1500 cm −1 in a mixed a
Autor:
J. Wharton, Benjamin Gilbert, Jeanne L. McHale, David N. McIlroy, Yongjun Geng, Robert M. Cohen, Luca Perfetti, Daqing Zhang, M. Grant Norton, B. Broocks, Gelsomina De Stasio, J. H. Streiff
Publikováno v:
Physical Review B. 60:4874-4879
Background: Guidelines addressing the management of venous thromboembolism (VTE) in cancer patients are heterogeneous and their implementation has been suboptimal worldwide. Objectives: To establish a common international consensus addressing practic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::1a32d896b4b18d48ecc1c63772e4d933
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3155185
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3155185
Background: Although long-term indwelling central venous catheters (CVCs) may lead to pulmonary embolism (PE) and loss of the CVC, there is lack of consensus on management of CVC-related thrombosis (CRT) in cancer patients and heterogeneity in clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::da449723a21db2b0950ea89f51934e14
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3156335
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3156335
Autor:
John H. Streiff, Keith A. Jones
Publikováno v:
Journal of chemical information and modeling. 48(10)
The main objective of this work was to characterize VA binding sites in multiple anesthetic target proteins. A computational algorithm was used to quantify the solvent exclusion and aliphatic character of amphiphilic pockets in the structures of VA b