Zobrazeno 1 - 10
of 59
pro vyhledávání: '"H. Steinbrecher"'
Autor:
Matthias Dewenter, Tilmann Seitz, Julia H. Steinbrecher, B. Daan Westenbrink, Haiyun Ling, Stephan E. Lehnart, Xander H.T. Wehrens, Johannes Backs, Joan Heller Brown, Lars S. Maier, Stefan Neef
Publikováno v:
ESC Heart Failure, Vol 11, Iss 4, Pp 2191-2199 (2024)
Abstract Aims Hyperactivity of Ca2+/calmodulin‐dependent protein kinase II (CaMKII) has emerged as a central cause of pathologic remodelling in heart failure. It has been suggested that CaMKII‐induced hyperphosphorylation of the ryanodine recepto
Externí odkaz:
https://doaj.org/article/811ff42f2bd046b0b243e4d8ccb5b35b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kai Schuh, Marco Abesser, Julia H. Steinbrecher, Julia U. Sprenger, Viacheslav O. Nikolaev, Ali El-Armouche, Ruwan K. Perera, Stephan E. Lehnart, Daniela Hübscher
Publikováno v:
Circulation Research. 116:1304-1311
Rationale : Cyclic nucleotides are second messengers that regulate cardiomyocyte function through compartmentalized signaling in discrete subcellular microdomains. However, the role of different microdomains and their changes in cardiac disease are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d300d6352d83431b26b63ee902fe58b
https://doi.org/10.1161/circresaha.116.306082
https://doi.org/10.1161/circresaha.116.306082
Autor:
Stephan E. Lehnart, Konrad R. Götz, Julia U. Sprenger, Michaela Kuhn, Julia Gorelik, Ruwan K. Perera, Jean-Luc Balligand, Viacheslav O. Nikolaev, Julia H. Steinbrecher
Publikováno v:
Circulation Research. 114:1235-1245
Rationale: 3′,5′-Cyclic guanosine monophosphate (cGMP) is an important second messenger that regulates cardiac contractility and protects the heart from hypertrophy. However, because of the lack of real-time imaging techniques, specific subcellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02efe847578248e746be2464d9d38e8
https://doi.org/10.1161/circresaha.114.302437
https://doi.org/10.1161/circresaha.114.302437
Autor:
N. Johal, L. Kitteringham, P. Malone, Michael Stanton, Stephen Griffin, M. Griffiths, H. Steinbrecher, S. Manoharan, David M. Burge, Robert Wheeler, J. Durell
Publikováno v:
Journal of pediatric urology. 12(4)
Summary Background With the Nordic consensus statement advocating orchidopexy at an earlier age, the present study sought to investigate the outcomes of primary paediatric orchidopexy at a tertiary UK centre. Objective To prospectively assess testicu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf315d741811a5e687368370b41ca88b
https://pubmed.ncbi.nlm.nih.gov/27422375
https://pubmed.ncbi.nlm.nih.gov/27422375
Autor:
Stefan Luther, Volker Westphal, M. Saleet Jafri, Tobias Kohl, Stefan W. Hell, Ulrich Parlitz, Stephan E. Lehnart, Eva Wagner, Jan Hendrik Streich, Brigitte Korff, Julia H. Steinbrecher, Hoang Trong M. Tuan, George S.B. Williams, Marcel A. Lauterbach, Gerd Hasenfuss, W. Jonathan Lederer, Brian M. Hagen
Publikováno v:
Circulation Research
Circulation Research; Vol 111
Circulation Research; Vol 111
Rationale: Transverse tubules (TTs) couple electric surface signals to remote intracellular Ca 2+ release units (CRUs). Diffraction-limited imaging studies have proposed loss of TT components as disease mechanism in heart failure (HF). Objectives: Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc744b1ee226480df19628e1336dfcb2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Julia U. Sprenger, Viacheslav O. Nikolaev, Lars S. Maier, Julia H. Steinbrecher, Gerd Hasenfuss, Ruwan K. Perera, Stephan E. Lehnart
Publikováno v:
Nature Communications. 6
3',5'-cyclic adenosine monophosphate (cAMP) is an ubiquitous second messenger that regulates physiological functions by acting in distinct subcellular microdomains. Although several targeted cAMP biosensors are developed and used in single cells, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e7592f0875ee4631b32d3e41b9c0a9
https://doi.org/10.1038/ncomms7965
https://doi.org/10.1038/ncomms7965
Autor:
Magdalena L. Bochenek, Julia H. Steinbrecher, Matthias Dobbelstein, Philip Wenzel, Stephan E. Lehnart, Katrin Schäfer, Elisabeth M. Zeisberg, Rajinikanth Gogiraju, Xingbo Xu, Michael Kessel
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association
Journal of the American Heart Association
Background Cardiac dysfunction developing in response to chronic pressure overload is associated with apoptotic cell death and myocardial vessel rarefaction. We examined whether deletion of tumor suppressor p53 in endothelial cells may prevent the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b3f3b8bed757c8122497e542f366c0
https://doi.org/10.1161/jaha.115.001770
https://doi.org/10.1161/jaha.115.001770
Publikováno v:
e & i Elektrotechnik und Informationstechnik. 122:131-135
Die Liberalisierung des Verkehrstragers Schiene in Europa und der damit verbundene diskriminierungsfreie Zugang zum Schienennetz schaffen neue Rahmenbedingungen fur die Betriebsfuhrung. Moderne, europaweit standardisierte Fahrweg- und Zugsicherungssy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cbaa3211850a5cb8ad2a4485059dbf
https://doi.org/10.1007/bf03054062
https://doi.org/10.1007/bf03054062