Zobrazeno 1 - 10
of 703
pro vyhledávání: '"H. Simons"'
Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia
Autor:
Reginald V.C.T. van der Kwast, Laura Parma, M. Leontien van der Bent, Eva van Ingen, Fabiana Baganha, Hendrika A.B. Peters, Eveline A.C. Goossens, Karin H. Simons, Meindert Palmen, Margreet R. de Vries, Paul H.A. Quax, A. Yaël Nossent
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 932-953 (2020)
Adenosine-to-inosine (A-to-I) editing in the seed sequence of microRNAs can shift the microRNAs’ targetomes and thus their function. Using public RNA-sequencing data, we identified 35 vasoactive microRNAs that are A-to-I edited. We quantified A-to-
Externí odkaz:
https://doaj.org/article/2209272f4f534aa0b0f07a3770ab3c50
Autor:
Eveline A. C. Goossens, Margreet R. de Vries, Karin H. Simons, Hein Putter, Paul H. A. Quax, A. Yaël Nossent
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Aims: MicroRNAs are regulators of (patho)physiological functions with tissue-specific expression patterns. However, little is known about inter-vascular differences in microRNA expression between blood vessel types or vascular beds. Differences in mi
Externí odkaz:
https://doaj.org/article/c96477a1f3944f549641f71977f9fb3b
Autor:
Karin H. Simons, Margreet R. de Vries, Hendrika A. B. Peters, J. Wouter Jukema, Paul H. A. Quax, Ramon Arens
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Aims: Vein grafts are frequently used conduits for arterial reconstruction in patients with cardiovascular disease. Unfortunately, vein graft disease (VGD) causes diminished patency rates. Innate immune system components are known to contribute to VG
Externí odkaz:
https://doaj.org/article/2a8ada1a2d364c178466a359c5850df5
Publikováno v:
IEEE Transactions on Services Computing. :1-14
Cloud computing depends on the dynamic allocation and release of resources, on demand, to meet heterogeneous computing needs. This is challenging for cloud data centers, which process huge amounts of data characterised by its high volume, velocity, v
Circulating Small Non-coding RNAs as Biomarkers for Recovery After Exhaustive or Repetitive Exercise
Autor:
Kjell E. J. Håkansson, Ove Sollie, Karin H. Simons, Paul H. A. Quax, Jørgen Jensen, A. Yaël Nossent
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Circulating microRNAs have proven to be reliable biomarkers, due to their high stability, both in vivo in the circulation, and ex vivo during sample preparation and storage. Small nucleolar RNAs (snoRNAs) are a different type of small non-coding RNAs
Externí odkaz:
https://doaj.org/article/77bd1bd0e9b449bd80511fdece40cc3f
Publikováno v:
Geoscientific Model Development, Vol 8, Iss 7, Pp 2009-2034 (2015)
This paper introduces and presents the Spatial Processes in HYdrology (SPHY) model (v2.0), its development background, its underlying concepts, and some example applications. SPHY has been developed with the explicit aim of simulating terrestrial hyd
Externí odkaz:
https://doaj.org/article/c1b61e7a1730413d8c125f450f953ea7
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Akademický článek
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Publikováno v:
The Yale journal of biology and medicine. 95(1)
Maternal prenatal distress is associated with child outcomes, including health, neurocognitive, and socio-emotional development. Knowledge on underlying mechanisms is limited, yet relevant for prevention and intervention. This study investigated whet
Publikováno v:
North American Journal of Fisheries Management. 40:17-28