Zobrazeno 1 - 10
of 62
pro vyhledávání: '"H. Scott Boswell"'
Autor:
Sisi Chen, Qiang Wang, Hao Yu, Maegan L. Capitano, Sasidhar Vemula, Sarah C. Nabinger, Rui Gao, Chonghua Yao, Michihiro Kobayashi, Zhuangzhuang Geng, Aidan Fahey, Danielle Henley, Stephen Z. Liu, Sergio Barajas, Wenjie Cai, Eric R. Wolf, Baskar Ramdas, Zhigang Cai, Hongyu Gao, Na Luo, Yang Sun, Terrence N. Wong, Daniel C. Link, Yunlong Liu, H. Scott Boswell, Lindsey D. Mayo, Gang Huang, Reuben Kapur, Mervin C. Yoder, Hal E. Broxmeyer, Zhonghua Gao, Yan Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Ageing is associated with clonal hematopoiesis of indeterminate potential (CHIP), which is linked to increased risks of hematological malignancies. Here the authors uncover an epigenetic mechanism through which mutant p53 drives clonal hematopoiesis
Externí odkaz:
https://doaj.org/article/1d5dfae220234a1b8cf7ca069a554a2a
Autor:
Sisi Chen, Qiang Wang, Hao Yu, Maegan L. Capitano, Sasidhar Vemula, Sarah C. Nabinger, Rui Gao, Chonghua Yao, Michihiro Kobayashi, Zhuangzhuang Geng, Aidan Fahey, Danielle Henley, Stephen Z. Liu, Sergio Barajas, Wenjie Cai, Eric R. Wolf, Baskar Ramdas, Zhigang Cai, Hongyu Gao, Na Luo, Yang Sun, Terrence N. Wong, Daniel C. Link, Yunlong Liu, H. Scott Boswell, Lindsey D. Mayo, Gang Huang, Reuben Kapur, Mervin C. Yoder, Hal E. Broxmeyer, Zhonghua Gao, Yan Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/8bd232b0dd00439a83f8274cced97810
Autor:
Anindya Chatterjee, Joydeep Ghosh, Baskar Ramdas, Raghuveer Singh Mali, Holly Martin, Michihiro Kobayashi, Sasidhar Vemula, Victor H. Canela, Emily R. Waskow, Valeria Visconte, Ramon V. Tiu, Catherine C. Smith, Neil Shah, Kevin D. Bunting, H. Scott Boswell, Yan Liu, Rebecca J. Chan, Reuben Kapur
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1333-1348 (2014)
Oncogenic mutations of FLT3 and KIT receptors are associated with poor survival in patients with acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs), and currently available drugs are largely ineffective. Although Stat5 has been impl
Externí odkaz:
https://doaj.org/article/3fb0e4f417624b859de3a4859396cf8a
Autor:
Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Publikováno v:
Blood. 141:244-259
Acute myeloid leukemia (AML) is an aggressive blood cancer with poor prognosis. FMS-like tyrosine kinase receptor-3 (FLT3) is one of the major oncogenic receptor tyrosine kinases aberrantly activated in AML. Although protein tyrosine phosphatase PRL2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba45e7977ff76b91425c2b3b3f267450
https://doi.org/10.1182/blood.2022016580
https://doi.org/10.1182/blood.2022016580
Autor:
H. Scott Boswell, Dhananjaya V. Kalvakolanu, Larry D. Cripe, Katie J. Sargent, Tareq Al Baghdadi, Angelo A. Cardoso, Sushil Gupta, Lang Li, Chirayu Goswami, Attaya Suvannasankha, Hamid Sayar, Annique Wilson-Weekes, Padmaja Gade, Rajasubramaniam Shanmugam
PDF file - 386K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c455c93ffb5973b340d7743901107a10
https://doi.org/10.1158/1078-0432.22443539
https://doi.org/10.1158/1078-0432.22443539
Autor:
H. Scott Boswell, Dhananjaya V. Kalvakolanu, Larry D. Cripe, Katie J. Sargent, Tareq Al Baghdadi, Angelo A. Cardoso, Sushil Gupta, Lang Li, Chirayu Goswami, Attaya Suvannasankha, Hamid Sayar, Annique Wilson-Weekes, Padmaja Gade, Rajasubramaniam Shanmugam
PDF file - 112K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b3a734d8fd261b40a46b90f077b1ec
https://doi.org/10.1158/1078-0432.22443536
https://doi.org/10.1158/1078-0432.22443536
Autor:
H. Scott Boswell, Dhananjaya V. Kalvakolanu, Larry D. Cripe, Katie J. Sargent, Tareq Al Baghdadi, Angelo A. Cardoso, Sushil Gupta, Lang Li, Chirayu Goswami, Attaya Suvannasankha, Hamid Sayar, Annique Wilson-Weekes, Padmaja Gade, Rajasubramaniam Shanmugam
Purpose: Death-associated protein kinase 1 (DAPK1), a tumor suppressor, is a rate-limiting effector in an endoplasmic reticulum (ER) stress-dependent apoptotic pathway. Its expression is epigenetically suppressed in several tumors. A mechanistic basi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1486f103c5d34ab5b6243f5eea2aa0
https://doi.org/10.1158/1078-0432.c.6519851
https://doi.org/10.1158/1078-0432.c.6519851
Autor:
Austyn Colter, James Ropa, Melissa L. Fishel, Brian Parkin, Maegan L. Capitano, Heiko Konig, George E. Sandusky, Claudiu T. Supuran, Callista Maguire, Fangli Chen, Daniela N. Petrusca, Max Jacobsen, Xue Wu, H. Scott Boswell, Emilia Licarete, Fabrizio Carta, Magdalena Czader
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute myeloid leukaemia (AML) is an aggressive form of blood cancer that carries a dismal prognosis. Several studies suggest that the poor outcome is due to a small fraction of leukaemic cells that elude treatment and survive in specialised, oxygen (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d49aaba6c4d2ef8619d6e0e11ad210
https://doi.org/10.1111/jcmm.17027
https://doi.org/10.1111/jcmm.17027
Autor:
Kinjal Bhadresha, Sanam Rezaei Benam, Alexander R. Maldeney, H. Scott Boswell, Reuben Kapur, Reza Shahbazi
Publikováno v:
Blood. 140:3397-3398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c1e24129685b301981e7b3ff134622d
https://doi.org/10.1182/blood-2022-169595
https://doi.org/10.1182/blood-2022-169595
Autor:
Justin Layer, Sravanti Rangaraju, Santhosh Pasupuleti, Larry D. Cripe, Hamid Sayar, Katie J Sargent, Jill Weisenbach, Huda S. Salman, G. David Roodman, Linsey Mayo, Reuben Kapur, Utpal P Dave', H. Scott Boswell
Publikováno v:
Blood. 140:11546-11547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f64ffc1dc5a933010665ca31d40c66
https://doi.org/10.1182/blood-2022-156329
https://doi.org/10.1182/blood-2022-156329