Zobrazeno 1 - 10
of 28
pro vyhledávání: '"H. Saragovi"'
Autor:
Omar Farnós, Shantoshini Dash, Cindy Chan, Hanan Chaabane, Uri H. Saragovi, Xingge Xu, Denis Leclerc, Alina Venereo-Sanchez, Janelle Sauvageau, Amine Kamen, Fouad Brahimi
Publikováno v:
Vaccines, Vol 8, Iss 654, p 654 (2020)
Vaccines
Volume 8
Issue 4
Vaccines
Volume 8
Issue 4
Vaccine design strategies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are focused on the Spike protein or its subunits as the main antigen target of neutralizing antibodies. In this work, we propose rapid production methods o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd0c06f28b7f0cdef00432048a0166b
https://www.mdpi.com/2076-393X/8/4/654
https://www.mdpi.com/2076-393X/8/4/654
Autor:
Tirzah J Weiss, Sung Ok Yoon, Youko Ikeda, Mitsuharu Yoshiyama, Stephanie L. Daugherty, Anastasia Soulas, Anthony Kanai, Nabila Saidi, Susan E. Malley, Nisha Ganesh, Uri H. Saragovi, Irina Zabbarova, William C. de Groat, Margaret A. Vizzard, Jae Cheon Ryu, Katharine Tooke, H. Francis Farhadi
Publikováno v:
Journal of Clinical Investigation. 128:1772-1786
Loss of bladder control is a challenging outcome facing patients with spinal cord injury (SCI). We report that systemic blocking of pro–nerve growth factor (proNGF) signaling through p75 with a CNS-penetrating small-molecule p75 inhibitor resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470032ce9944cdf031b6a30d4c873260
https://doi.org/10.1172/jci97837
https://doi.org/10.1172/jci97837
Autor:
Andrea A. Baccarelli, Mark Basik, Saima Hassan, Louis Gaboury, Ombretta Salvucci, Cristiano Ferrario, Uri H. Saragovi, Louise A. Quenneville
Publikováno v:
The American Journal of Pathology. 175:66-73
The chemokine stromal cell-derived factor-1 (SDF-1) may function to attract CXCR4-expressing cancer cells to metastatic organs. We have previously demonstrated that low plasma SDF-1, a host-derived marker, increases distant metastatic risk in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f804ca512d7ef5f1cc905d0537237efa
https://doi.org/10.2353/ajpath.2009.080948
https://doi.org/10.2353/ajpath.2009.080948
Autor:
Michael D.C. Evans, Ervin B. Podgorsak, Micheline Gosselin, Nada Tomic, Uri H. Saragovi, Slobodan Devic, Jonathan F Wan
Publikováno v:
Physics in Medicine and Biology. 52:3121-3131
We describe a technique for the MTT assay that irradiates all cells at once by a combination of couch movement and a step-and-shoot irradiation technique on a linear accelerator with 6 MV and 18 MV photon beams. In two experimental setups, we obtaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516bb4d56c1552840c14ff645e4e2231
https://doi.org/10.1088/0031-9155/52/11/013
https://doi.org/10.1088/0031-9155/52/11/013
Autor:
Marcelo Rudzinski, H. Saragovi
Publikováno v:
Current Medicinal Chemistry-Central Nervous System Agents. 5:43-49
Glaucoma is a neurodegenerative disorder that affects the optic nerve and the inner layers of the retina. In- creased intraocular pressure is a major risk factor in the disease. Chronic elevation of intraocular pressure specifically in- duces the dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2efdcd6a465e04cc4df340975517e65
https://doi.org/10.2174/1568015053202796
https://doi.org/10.2174/1568015053202796
Autor:
Yujing, Bai, Yingting, Zhu, Qin, Chen, Jing, Xu, Marinko V, Sarunic, Uri H, Saragovi, Yehong, Zhuo
Publikováno v:
Chinese medical journal. 127(2)
Glaucoma, an irreversible optic nerve neuropathy, always results in blindness. This study aimed to evaluate glaucoma-like features in the rat episcleral vein cauterization (EVC) model by multiple in vivo and in vitro evidences.Wistar rat was used in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f01902a908adb78e75b9edc77ea70021
https://pubmed.ncbi.nlm.nih.gov/24438629
https://pubmed.ncbi.nlm.nih.gov/24438629
Autor:
Maryam Taheri, Joe Makkerh, Uri H. Saragovi, John S. Mort, Clifford P. Stanners, Abraham Fuks
Publikováno v:
Journal of Biological Chemistry. 275:26935-26943
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bcc3fe3452b5c445aae4b2377ad2bf
https://doi.org/10.1016/s0021-9258(19)61463-8
https://doi.org/10.1016/s0021-9258(19)61463-8
Publikováno v:
Current protocols in immunology.
One of the most widely studied lymphokine systems is the T lymphocyte growth factor interleukin 2 (IL-2). This unit describes two basic methods for the quantitation and biochemical characterization of IL-2 receptors. The first method employs the radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e337da6f9f97b71d877690a95885089f
https://pubmed.ncbi.nlm.nih.gov/18432801
https://pubmed.ncbi.nlm.nih.gov/18432801
Autor:
H Saragovi, T R Malek
Publikováno v:
Proceedings of the National Academy of Sciences. 87:11-15
Previous studies have indicated that high-affinity interleukin 2 receptors (IL-2R) are comprised of at least two distinct noncovalently associated subunits of Mr 55,000 (p55) and Mr 75,000 (p75). To biochemically characterize p75, we have directly is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bf2f0821a27b65f1caa9f958de40aa
https://doi.org/10.1073/pnas.87.1.11
https://doi.org/10.1073/pnas.87.1.11
Publikováno v:
Journal of medicinal chemistry. 45(20)
beta-Turn peptidomimetics 1 were designed to mimic hot spots of neurotrophin-3 (NT-3) and others. Solid-phase syntheses of these were developed, though limitations were encountered with scale-up. Consequently, an alternative design with 2 was investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcf10462a7856c6fd05528dc3b87a4f
https://pubmed.ncbi.nlm.nih.gov/12238916
https://pubmed.ncbi.nlm.nih.gov/12238916