Výsledky vyhledávání - "H. Samuel Wieand"

Prognostic and Predictive Roles of High-Degree Microsatellite Instability in Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

Autor: Norman Wolmark, Carmen J. Allegra, Soonmyung Paik, Linda H. Colangelo, Ilan R. Kirsch, George P. Kim, H. Samuel Wieand

Publikováno v: Journal of Clinical Oncology. 25:767-772

Purpose The role of high-degree microsatellite instability (MSI-H) as a marker to predict benefit from adjuvant chemotherapy remains unclear. Patients and Methods To help define its impact, we conducted an analysis of National Surgical Adjuvant Breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3015ce16bcb3652ad1990f9519bf442
https://doi.org/10.1200/jco.2006.05.8172

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Quality of Life in Operable Colon Cancer Patients Receiving Oral Compared With Intravenous Chemotherapy: Results From National Surgical Adjuvant Breast and Bowel Project Trial C-06

Autor: Greg Yothers, Patricia A. Ganz, Norman Wolmark, Barry C. Lembersky, Stephanie R. Land, Jacek A. Kopec, H. Samuel Wieand, Reena S. Cecchini

Publikováno v: Journal of Clinical Oncology. 25:424-430

Purpose We compared health-related quality of life (HRQL), symptoms, and convenience of care (COC) in patients with stage II/III carcinoma of the colon who received either oral uracil/ftorafur (UFT) plus leucovorin (LV) or standard intravenous (IV) f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6563915fff71656e70cbf2a98fdd56
https://doi.org/10.1200/jco.2005.05.2597

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Breast Cancer-Related Lymphedema ? What Are the Significant Predictors and How They Affect the Severity of Lymphedema?

Autor: Victor G. Vogel, H. Samuel Wieand, Atilla Soran, Ronald Johnson, Ali Harlak, Gina D'Angelo, Figen Ardic, Mirsada Begovic

Publikováno v: The Breast Journal. 12:536-543

According to the American Cancer Society, there are currently 2 million breast cancer (BC) survivors in the USA and 20% of them cope with lymphedema (LE). The primary aim of this study was to determine the predictive factors of BC-related LE. The sec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c910207da0ead565e7a15e53748c346
https://doi.org/10.1111/j.1524-4741.2006.00342.x

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Pemetrexed/Oxaliplatin for First-Line Treatment of Patients with Advanced Colorectal Cancer: A Phase II Trial of the National Surgical Adjuvant Breast and Bowel Project Foundation Research Program

Autor: James N. Atkins, Barbara J. Miller, Norman Wolmark, Terrence P. Cescon, J. Philip Kuebler, William J. John, Victor G. Vogel, Roy E. Smith, Charles E. Geyer, Samuel A. Jacobs, Linda H. Colangelo, H. Samuel Wieand

Publikováno v: Clinical Colorectal Cancer. 5:181-187

Background Pemetrexed and oxaliplatin have clinical activity as single agents in colorectal cancer (response rates, 10%-17%). In this study, these drugs were used in combination as first-line therapy in a group of patients with metastatic colorectal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c529bd6d3554399f8e6891e8e8559106
https://doi.org/10.3816/ccc.2005.n.029

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Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual

Publikováno v: Surgical Clinics of North America. 83:803-819

Since its inception, the AJCC staging system for breast cancer has been in an almost constant state of evolution, striving with each revision to reflect the most up-to-date clinical research as well as the widespread consensus among physicians about

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ad497e884123a708d17ce3be5ba28c
https://doi.org/10.1016/s0039-6109(03)00034-3

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Prognostic Value of Thymidylate Synthase, Ki-67, and p53 in Patients With Dukes’ B and C Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

Autor: H. Samuel Wieand, Pamela M. Klein, Soon Paik, Ilan R. Kirsch, Linda H. Colangelo, Norman Wolmark, George P. Kim, Carmen J. Allegra, Allyson L. Parr, Patrick G. Johnston

Publikováno v: Journal of Clinical Oncology. 21:241-250

Purpose: To define the value of thymidylate synthase (TS), Ki-67, and p53 as prognostic markers in patients with stage II and III colon carcinoma. Patients and Methods: We retrospectively analyzed the prognostic value of TS, Ki-67, and p53 in 706 pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2ca4f0e394973b3acc1d05ee76a329
https://doi.org/10.1200/jco.2003.05.044

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Early Stopping of a Clinical Trial When There is Evidence of No Treatment Benefit

Autor: Bernard Fisher, John Bryant, H. Samuel Wieand, Norman Wolmark, James J. Dignam

Publikováno v: Controlled Clinical Trials. 19:575-588

Although several randomized clinical trials in the 1980s indicated a benefit from the use of tamoxifen in the treatment of early-stage breast cancer, questions have remained regarding the optimal duration of drug administration. In 1982, the National

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::625fd70d807c0dcc7e01d564db4c9629
https://doi.org/10.1016/s0197-2456(98)00041-5

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Neurotoxicity from oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: NSABP C-07

Autor: Roy E. Smith, Reena S. Cecchini, David Cella, Eduardo R. Pajon, Michael O’Connell, Burton M. Needles, Thomas E. Seay, Jacek A. Kopec, Norman Wolmark, Patricia A. Ganz, Linda H. Colangelo, J. Philip Kuebler, James D. Bearden, Lauren K. Colman, Stephanie R. Land, Keith S. Lanier, Joseph P. Costantino, H. Samuel Wieand, Kate Murphy

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 25(16)

Purpose The randomized, multicenter, phase III protocol C-07 compared the efficacy of adjuvant bolus fluorouracil and leucovorin (FULV) versus FULV with oxaliplatin (FLOX) in stage II or III colon cancer. Definitive analysis revealed an increase in 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d219bf5c55217856adeb2c4b55aa0cb2
https://pubmed.ncbi.nlm.nih.gov/17470848

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